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  • 豨莶精醇

    Darutigenol

    豨莶精醇
    产品编号 CFN97006
    CAS编号 5940-00-1
    分子式 = 分子量 C20H34O3 = 322.5
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Diterpenoids
    植物来源 The herbs of Siegesbeckia orientalis.
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    豨莶精醇 CFN97006 5940-00-1 1mg QQ客服:1413575084
    豨莶精醇 CFN97006 5940-00-1 5mg QQ客服:1413575084
    豨莶精醇 CFN97006 5940-00-1 10mg QQ客服:1413575084
    豨莶精醇 CFN97006 5940-00-1 20mg QQ客服:1413575084
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
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  • Instituto Politécnico de Bragan?a (Portugal)
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  • University of Fribourg (Switzerland)
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  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • HIV Med.2021, 22(8):690-704.
  • Vojnosanit Pregl2016, 75(00):391-391
  • Journal of Functional Foods2022, 96: 105216.
  • Cells.2022, 11(8), 1311.
  • Pharmaceutics.2020, 12(9):882.
  • Korean Journal of Plant Resources2021, 34(1):52-58.
  • Biochem Biophys Res Commun.2018, 495(1):1271-1277
  • Viruses.2017, 9(10)
  • ACS Omega2020, 5,33,20825-20830
  • Nanjing University of Chinese Medicine2022, 345930.
  • Int J Mol Sci.2023, 24(5):4505.
  • J Agric Food Chem.2016, 64(35):6783-90
  • J Biochem Mol Toxicol.2022, e23211.
  • Food Bioscience2023, 56:103311.
  • VNU Journal of Science2023, 39(2):24-33.
  • J Appl Biol Chem.2022, 65(4):pp.463-469.
  • Nat Prod Sci.2019, 25(3):238
  • Molecules.2022, 27(4):1412.
  • Sci Rep.2015, 5:13194
  • J. Food Composition and Anal.2022, V 109:104482.
  • LWT-Food Sci Technol2020, 109163
  • Sci Rep.2019, 9(1):4646
  • Korean J. Medicinal Crop Sci.2018, 26(2):148-156
  • ...
  • 生物活性
    Description: Darutigenol has obvious antithrombotic effect,its mechanism may be related to inhibition of platelet aggregation and adhesion.
    In vitro:
    Talanta. 2012 Jan 30;89:505-12.
    Molecularly imprinted polymer for the specific solid-phase extraction of kirenol from Siegesbeckia pubescens herbal extract.[Pubmed: 22284524]
    Molecular imprinted polymers (MIPs) were prepared by thermal polymerization using a non-covalent molecularly imprinting strategy with kirenol as the template, acrylamide (AM) as the functional monomer and ethylene glycol dimethacrylamide (EGDMA) as the cross-linker in the porogen of tetrahydrofuran (THF).
    METHODS AND RESULTS:
    The synthesized MIPs were characterized by scanning electron microscopy (SEM) and Fourier transform infrared (FT-IR). Its molecular recognition property was investigated by UV spectrogram. High-pressure liquid chromatography (HPLC) was used for analysis of target analytes. The polymers were evaluated further by batch rebinding experiments, and from the derived isotherms their binding capacity and binding strength were determined. Then the selectivity of the MIPs was checked toward the selected structurally related compounds and the recognition coefficients for kirenol, darutigenol, and ent-2-oxo-15, 16, 19-trihydroxypimar-8(14)-ene (TD) were 2.47, 3.43 and 3.40, respectively. The properties of MIPs for SPE were also evaluated.
    CONCLUSIONS:
    The results obtained demonstrate that the good imprinting effect and the excellent selectivity of MIPs were obtained. The optimized molecular imprinted SPE procedure was applied to extract kirenol directly from the extracts of the aerial part of Siegesbeckia pubescens herb. A selective extraction of kirenol from traditional Chinese medicine (TCM) was achieved with extraction yield of 80.9%.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 3.1008 mL 15.5039 mL 31.0078 mL 62.0155 mL 77.5194 mL
    5 mM 0.6202 mL 3.1008 mL 6.2016 mL 12.4031 mL 15.5039 mL
    10 mM 0.3101 mL 1.5504 mL 3.1008 mL 6.2016 mL 7.7519 mL
    50 mM 0.062 mL 0.3101 mL 0.6202 mL 1.2403 mL 1.5504 mL
    100 mM 0.031 mL 0.155 mL 0.3101 mL 0.6202 mL 0.7752 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    奇壬醇; Kirenol CFN98867 52659-56-0 C20H34O4 = 338.5 20mg QQ客服:1413575084
    9-羟基豨莶精醇; 9-Hydroxydarutigenol CFN99292 1188282-00-9 C20H34O4 = 338.5 5mg QQ客服:215959384
    7-羟基豨莶精醇; 7-Hydroxydarutigenol CFN99291 1188281-99-3 C20H34O4 = 338.5 5mg QQ客服:1457312923
    豨莶精醇; Darutigenol CFN97006 5940-00-1 C20H34O3 = 322.5 5mg QQ客服:215959384
    豯莶苷; Darutoside CFN97004 59219-65-7 C26H44O8 = 484.6 20mg QQ客服:3257982914
    16-O-乙酰豨莶精醇; 16-O-Acetyldarutigenol CFN99293 1188282-01-0 C22H36O4 = 364.5 5mg QQ客服:3257982914
    Hythiemoside A; Hythiemoside A CFN97415 853267-91-1 C28H46O9 = 526.7 5mg QQ客服:3257982914
    Hythiemoside B; Hythiemoside B CFN91141 853267-90-0 C28H46O9 = 526.7 5mg QQ客服:3257982914
    15,16-二-O-乙酰基豯莶苷; 15,16-Di-O-acetyldarutoside CFN99294 1188282-02-1 C30H48O10 = 568.7 5mg QQ客服:2159513211
    ent-14,16-环氧基-8-海松烯-3,15-二醇; ent-14,16-Epoxy-8-pimarene-3,15-diol CFN99290 1188281-98-2 C20H32O3 = 320.5 5mg QQ客服:3257982914

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