Cyclocommunol

	产品编号	CFN92418
	CAS编号	145643-96-5
	分子式 = 分子量	C₂₀H₁₆O₆ = 352.3
	产品纯度	>=98%
	物理属性	Yellow cryst.
	化合物类型	Flavonoids
	植物来源	The root barks of Morus alba L.
ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用

提供自定义包装

产品名称	产品编号	CAS编号	包装	QQ客服
Cyclocommunol	CFN92418	145643-96-5	1mg	QQ客服：215959384
Cyclocommunol	CFN92418	145643-96-5	5mg	QQ客服：215959384
Cyclocommunol	CFN92418	145643-96-5	10mg	QQ客服：215959384
Cyclocommunol	CFN92418	145643-96-5	20mg	QQ客服：215959384

存储与注意事项

1. 在您收到产品后请检查产品。如无问题，请将产品存入冰霜并且样品瓶保持密封，产品可以存放长达24个月（2-8摄氏度）。

2. 只要有可能，产品溶解后，您应该在同一天应用于您的实验。但是，如果您需要提前做预实验，或者需要全部溶解，我们建议您将溶液以等分试样的形式存放在-20℃的密封小瓶中。通常，这些可用于长达两周。使用前，打开样品瓶前，我们建议您将产品平衡至室温至少1小时。

3. 需要更多关于溶解度，使用和处理的建议？请发送电子邮件至：service@chemfaces.com

订购流程

1. 在线订购

请联系我们QQ客服

2. 电话订购

请拨打电话：
027-84237683 或 027-84237783

3. 邮件或传真订购

发送电子邮件到: manager@chemfaces.com 或
发送传真到：027-84254680

提供订购信息

为了方便客户的订购，请需要订购ChemFaces产品的客户，在下单的时候请提供下列信息，以供我们快速为您建立发货信息。

1. 产品编号（CAS No.或产品名称）

2. 发货地址

3. 联系方法 (联系人，电话）

4. 开票抬头 (如果需要发票的客户）

5. 发票地址（发货地址与发票地址不同）

发货时间

1. 付款方式为100%预付款客户，我们将在确认收到货款后当天或1-3个工作日发货。

2. 付款方式为月结的客户，我们承诺在收到订单后当天或1-3个工作日内发货。

3. 如果客户所需要的产品，需要重新生产，我们有权告知客户，交货时间需要延期。

ChemFaces的产品在许多优秀和顶级科学期刊中被引用

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089

Medical University of Gdansk (Poland)

Institute of Pathophysiology Medical University of Vienna (Austria)

Agricultural Research Organization (ARO) (Israel)

Guangzhou Institutes of Biomedicine and Health (China)

Leibniz Institute of Plant Biochemistry (Germany)

Heinrich-Heine-University Düsseldorf (Germany)

University of Vienna (Austria)

Instituto Politécnico de Bragan?a (Portugal)

Heidelberg University (Germany)

Warszawski Uniwersytet Medyczny (Poland)

Sanford Burnham Medical Research Institute (USA)

University of South Australia (Australia)

Celltrion Chemical Research Institute (Korea)

China Medical University (Taiwan)

More...

Description:

Cyclocommunol exhibits cytotoxicity against hepatocellular carcinoma (SMMC-7721) and gastric carcinoma (BGC-823 and SGC-7901) cell lines. It also shows strong inhibition of arachidonic acid (AA)- and collagen-induced platelet aggregation.

Targets:

PAFR

In vitro:

J Asian Nat Prod Res. 2010 Jul;12(7):586-92.

New isoprenylated flavonoids and cytotoxic constituents from Artocarpus tonkinensis.[Pubmed: 20628938]

METHODS AND RESULTS:
Two new isoprenylated flavonoids, artotonins A and B (1 and 2), along with 13 known compounds (3-15), were isolated from the roots of Artocarpus tonkinensis A. Chev. ex Gagnep. The structures were elucidated by spectroscopic methods.
CONCLUSIONS:
Cyclocommunol (6), isocyclomulberrin (7), cudraflavone C (11), and morusin (13) exhibited cytotoxicity against hepatocellular carcinoma (SMMC-7721) and gastric carcinoma (BGC-823 and SGC-7901) cell lines.

Biochem Pharmacol. 1993 Jan 26;45(2):509-12.

Antiplatelet activity of some prenylflavonoids.[Pubmed: 8435100]

Eight naturally occurring prenylflavonoids were tested for their antiplatelet activities in rabbit platelet suspension.
METHODS AND RESULTS:
Cyclomorusin and artomunoxanthone showed strong inhibition of platelet-activating factor (PAF; 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine) induced platelet aggregation. Cyclomulberrin, dihydroisocycloartomunin, Cyclocommunol and cyclocommunin showed strong inhibition of arachidonic acid (AA)- and collagen-induced platelet aggregation. Cyclomorusin also inhibited markedly collagen-induced platelet aggregation. Cyclocommunin, dihydroisocycloartomunin and cyclomulberrin also showed slight but significant antiplatelet effects on the aggregation induced by PAF.
CONCLUSIONS:
Of the compounds tested, cyclocommunin exhibited the most potent inhibition of platelet aggregation induced by collagen (IC50 = 14.4 microM) and AA (IC50 = 12.5 microM). Thromboxane B2 formation caused by AA was suppressed by cyclocommunin and artomunoxanthone.

产品名称	产品编号	CAS编号	分子式 = 分子量	位单	联系QQ
Cyclocommunol; Cyclocommunol	CFN92418	145643-96-5	C₂₀H₁₆O₆ = 352.3	5mg	QQ客服：2056216494
环桑素; Cyclomulberrin	CFN92417	19275-51-5	C₂₅H₂₄O₆ = 420.5	5mg	QQ客服：3257982914
环桑色烯; Cyclomorusin	CFN97714	62596-34-3	C₂₅H₂₂O₆ = 418.45	5mg	QQ客服：1413575084
新环桑色烯; Neocyclomorusin	CFN92694	62596-35-4	C₂₅H₂₄O₇ = 436.5	5mg	QQ客服：3257982914
Artoheterophyllin B; Artoheterophyllin B	CFN99273	1174017-37-8	C₃₀H₃₂O₇ = 504.6	5mg	QQ客服：2159513211
异叶波罗蜜环黄酮素; Cycloheterophyllin	CFN97748	36545-53-6	C₃₀H₃₀O₇ = 502.56	5mg	QQ客服：1457312923

信息支持

公司简介
订购流程
付款方式
退换货政策

ChemFaces提供的产品仅用于科学研究使用，不用于诊断或治疗程序。

联系方式

电机：027-84237783
传真：027-84254680
在线QQ: 1413575084
E-Mail：manager@chemfaces.com

湖北省武汉沌口经济技术开区车城南路83号1号楼第三层厂房

ChemFaces为科学家，科研人员与企业提供快速的产品递送。我们通过瑞士SGS ISO 9001:2008质量体系认证天然化合物与对照品的研发和生产。

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	2.8385 mL	14.1924 mL	28.3849 mL	56.7698 mL	70.9622 mL
5 mM	0.5677 mL	2.8385 mL	5.677 mL	11.354 mL	14.1924 mL
10 mM	0.2838 mL	1.4192 mL	2.8385 mL	5.677 mL	7.0962 mL
50 mM	0.0568 mL	0.2838 mL	0.5677 mL	1.1354 mL	1.4192 mL
100 mM	0.0284 mL	0.1419 mL	0.2838 mL	0.5677 mL	0.7096 mL