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  • 沙苑子苷A

    Complanatoside A

    沙苑子苷A
    产品编号 CFN99525
    CAS编号 146501-37-3
    分子式 = 分子量 C27H30O18 = 642.5
    产品纯度 >=98%
    物理属性 Yellow powder
    化合物类型 Flavonoids
    植物来源 The seeds of Astragalus complanatus
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    沙苑子苷A CFN99525 146501-37-3 1mg QQ客服:2159513211
    沙苑子苷A CFN99525 146501-37-3 5mg QQ客服:2159513211
    沙苑子苷A CFN99525 146501-37-3 10mg QQ客服:2159513211
    沙苑子苷A CFN99525 146501-37-3 20mg QQ客服:2159513211
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
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    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
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  • Universidad Veracuzana (Mexico)
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  • Pennsylvania State University (USA)
  • Korea Institute of Oriental Medicine (Korea)
  • Research Unit Molecular Epigenetics (MEG) (Germany)
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  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Antiviral Res.2013, 98(3):386-93
  • New Zealand J. Forestry Sci.2014, 44:17
  • China Pharmacy2015, 26(27)
  • Am J Chin Med.2015, 30:1-22
  • J Chromatogr Sci.2015, 53(5):824-9
  • Food Chem.2017, 221:1135-1144
  • Plant Cell Tiss Org2017, 479-486
  • Biochem Biophys Res Commun.2017, 494(3-4):587-593
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  • Journal of Analytical Chemistry2017, 854-861
  • Sci Rep. 2018, 10590
  • Int J Mol Sci.2018, 19(9):E2681
  • Life Sci.2018, 209:498-506
  • Asian Journal of Chemistry2018, 30(12):2699-2703
  • RSC Adv.2018, 32621-32636
  • Sci Rep. 2018, 462(8)
  • J Cancer.2019, 10(23):5843-5851
  • Molecules.2019, 24(24):E4536
  • Toxicol Res.2019, 35(4):371-387
  • Pharmaceutical Chemistry Journal2019, 52(12):986-991
  • Phytomedicine.2019, 59:152785
  • Process Biochemistry2019, 85:106-115
  • TCI CO.2019, US20190151281A1
  • ...
  • 生物活性
    Description: Complanatoside A is a flavonol glycoside isolated from Astragalus complanatus, and currently it is used as a quality control index for A. complanatus in the 2010 edition of the Chinese Pharmacopoeia.
    In vitro:
    Biomed Chromatogr. 2016 Jun;30(6):888-93.
    Quantification of complanatoside A in rat plasma using LC-MS/MS and its application to a pharmacokinetic study.[Pubmed: 26393341]
    Complanatoside A is a flavonol glycoside isolated from Astragalus complanatus, and currently it is used as a quality control index for A. complanatus in the 2010 edition of the Chinese Pharmacopoeia.
    METHODS AND RESULTS:
    For the first time, a simple and sensitive LC-MS/MS method was developed for the determination of Complanatoside A in rat plasma over the range of 2.3-575 ng/mL. Complanatoside A was extracted from plasma by a protein precipitation procedure, separated by LC and detected by MS/MS in positive electrospray ionization mode. The method was validated for selectivity, carryover, sensitivity, linearity, extraction recovery, matrix effect, accuracy, precision and stability studies. The lower limit of quantification was established at 2.3 ng/mL. Intra- and inter-day precisions (LLOQ, low-QC, med-QC and high-QC) were <7.9%, and accuracies were between 94.0 and 105.1%. Matrix effect was acceptable (97.9-103.0%) and extraction recovery was reproducible (88.5-94.4%). Complanatoside A was stable in the investigated conditions.
    CONCLUSIONS:
    The method was applied to the pharmacokinetics of Complanatoside A in rats.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 1.5564 mL 7.7821 mL 15.5642 mL 31.1284 mL 38.9105 mL
    5 mM 0.3113 mL 1.5564 mL 3.1128 mL 6.2257 mL 7.7821 mL
    10 mM 0.1556 mL 0.7782 mL 1.5564 mL 3.1128 mL 3.8911 mL
    50 mM 0.0311 mL 0.1556 mL 0.3113 mL 0.6226 mL 0.7782 mL
    100 mM 0.0156 mL 0.0778 mL 0.1556 mL 0.3113 mL 0.3891 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    2″-O-没食子酰基杨梅苷; 2''-O-Galloylmyricitrin CFN95046 56939-52-7 C28H24O16 = 616.5 5mg QQ客服:3257982914
    3''-O-没食子酰基杨梅苷; 3''-O-Galloylmyricitrin CFN95057 143202-36-2 C28H24O16 = 616.5 5mg QQ客服:2159513211
    杨梅酮3-O-半乳糖苷; Myricetin 3-O-galactoside CFN97817 15648-86-9 C21H20O13 = 480.38 10mg QQ客服:3257982914
    杨梅素-3-O-β-D-葡萄糖苷; Myricetin 3-O-beta-D-glucopyranoside CFN80163 19833-12-6 C21H20O13 = 480.4 5mg QQ客服:2932563308
    杨梅素-3-O-β-D-木糖(1-2)-β-D-葡萄糖苷; Myricetin 3-O-beta-D-xylopyranosyl(1-2)-beta-D-glucopyranoside CFN80126 142449-93-2 C26H28O17 = 612.13 5mg QQ客服:1413575084
    杨梅素-3-O-β-D-木糖(1-2)-[α-L-鼠李糖-(1-6)]-β-D-葡萄糖苷; Myricetin 3-O-beta-D-xylopyranosyl(1-2)-[alpha-L-rhamnopyranosyl-(1-6)]-beta-D-glucopyranoside CFN80330 N/A C32H38O21 = 758.63 5mg QQ客服:1148253675
    沙苑子苷A; Complanatoside A CFN99525 146501-37-3 C27H30O18 = 642.5 5mg QQ客服:2159513211
    杨梅酮 4'-甲醚-3-O-鼠李糖苷; Mearnsitrin CFN98387 30484-88-9 C22H22O12 = 478.4 5mg QQ客服:2159513211
    落叶黄素-3-O-β-D-葡萄糖苷; Laricitrin 3-O-glucoside CFN80175 39986-90-8 C22H22O13 = 494.10 5mg QQ客服:1413575084
    丁香亭-3-O-葡糖苷; Syringetin-3-O-glucoside CFN90468 40039-49-4 C23H24O13 = 508.43 5mg QQ客服:1413575084

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