沙苑子苷A

Complanatoside A

	产品编号	CFN99525
	CAS编号	146501-37-3
	分子式 = 分子量	C₂₇H₃₀O₁₈ = 642.5
	产品纯度	>=98%
	物理属性	Yellow powder
	化合物类型	Flavonoids
	植物来源	The seeds of Astragalus complanatus
ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用

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产品名称	产品编号	CAS编号	包装	QQ客服
沙苑子苷A	CFN99525	146501-37-3	1mg	QQ客服：1457312923
沙苑子苷A	CFN99525	146501-37-3	5mg	QQ客服：1457312923
沙苑子苷A	CFN99525	146501-37-3	10mg	QQ客服：1457312923
沙苑子苷A	CFN99525	146501-37-3	20mg	QQ客服：1457312923

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ChemFaces的产品在许多优秀和顶级科学期刊中被引用

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089

Tohoku University (Japan)

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Center for protein Engineering (CIP) (Belgium)

Harvard University (USA)

Sanford Burnham Medical Research Institute (USA)

Weizmann Institute of Science (Israel)

Universidade Federal de Goias (UFG) (Brazil)

University of South Australia (Australia)

Utrecht University (Netherlands)

Tokyo Woman's Christian University (Japan)

University of Melbourne (Australia)

Charles University in Prague (Czech Republic)

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Description:

Complanatoside A is a flavonol glycoside isolated from Astragalus complanatus, and currently it is used as a quality control index for A. complanatus in the 2010 edition of the Chinese Pharmacopoeia.

In vitro:

Biomed Chromatogr. 2016 Jun;30(6):888-93.

Quantification of complanatoside A in rat plasma using LC-MS/MS and its application to a pharmacokinetic study.[Pubmed: 26393341]

Complanatoside A is a flavonol glycoside isolated from Astragalus complanatus, and currently it is used as a quality control index for A. complanatus in the 2010 edition of the Chinese Pharmacopoeia.
METHODS AND RESULTS:
For the first time, a simple and sensitive LC-MS/MS method was developed for the determination of Complanatoside A in rat plasma over the range of 2.3-575 ng/mL. Complanatoside A was extracted from plasma by a protein precipitation procedure, separated by LC and detected by MS/MS in positive electrospray ionization mode. The method was validated for selectivity, carryover, sensitivity, linearity, extraction recovery, matrix effect, accuracy, precision and stability studies. The lower limit of quantification was established at 2.3 ng/mL. Intra- and inter-day precisions (LLOQ, low-QC, med-QC and high-QC) were <7.9%, and accuracies were between 94.0 and 105.1%. Matrix effect was acceptable (97.9-103.0%) and extraction recovery was reproducible (88.5-94.4%). Complanatoside A was stable in the investigated conditions.
CONCLUSIONS:
The method was applied to the pharmacokinetics of Complanatoside A in rats.

产品名称	产品编号	CAS编号	分子式 = 分子量	位单	联系QQ
丁香亭-3-O-半乳糖苷; Syringetin 3-O-galactoside	CFN70408	55025-56-4	C₂₃H₂₄O₁₃ = 508.4	5mg	QQ客服：2159513211
丁香亭-3-O-芸香糖苷; Syringetin-3-O-rutinoside	CFN91150	53430-50-5	C₂₉H₃₄O₁₇ = 654.6	5mg	QQ客服：2159513211
杨梅苷；五羟基黄酮-3-鼠李糖苷; Myricitrin	CFN99840	17912-87-7	C₂₁H₂₀O₁₂ = 464.4	20mg	QQ客服：2159513211
2″-O-没食子酰基杨梅苷; 2''-O-Galloylmyricitrin	CFN95046	56939-52-7	C₂₈H₂₄O₁₆ = 616.5	5mg	QQ客服：1457312923
3''-O-没食子酰基杨梅苷; 3''-O-Galloylmyricitrin	CFN95057	143202-36-2	C₂₈H₂₄O₁₆ = 616.5	5mg	QQ客服：2056216494
杨梅酮3-O-半乳糖苷; Myricetin 3-O-galactoside	CFN97817	15648-86-9	C₂₁H₂₀O₁₃ = 480.38	10mg	QQ客服：2159513211
杨梅素-3-O-β-D-葡萄糖苷; Myricetin 3-O-beta-D-glucopyranoside	CFN80163	19833-12-6	C₂₁H₂₀O₁₃ = 480.4	5mg	QQ客服：2159513211
杨梅素-3-O-β-D-木糖（1-2）-β-D-葡萄糖苷; Myricetin 3-O-beta-D-xylopyranosyl(1-2)-beta-D-glucopyranoside	CFN80126	142449-93-2	C₂₆H₂₈O₁₇ = 612.13	5mg	QQ客服：1413575084
杨梅素-3-O-β-D-木糖（1-2）-[α-L-鼠李糖-(1-6)]-β-D-葡萄糖苷; Myricetin 3-O-beta-D-xylopyranosyl(1-2)-[alpha-L-rhamnopyranosyl-(1-6)]-beta-D-glucopyranoside	CFN80330	N/A	C₃₂H₃₈O₂₁ = 758.63	5mg	QQ客服：3257982914
杨梅素-3'-O-β-D-葡萄糖苷; Cannabiscitrin	CFN95278	520-14-9	C₂₁H₂₀O₁₃ = 480.4	5mg	QQ客服：1457312923

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	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	1.5564 mL	7.7821 mL	15.5642 mL	31.1284 mL	38.9105 mL
5 mM	0.3113 mL	1.5564 mL	3.1128 mL	6.2257 mL	7.7821 mL
10 mM	0.1556 mL	0.7782 mL	1.5564 mL	3.1128 mL	3.8911 mL
50 mM	0.0311 mL	0.1556 mL	0.3113 mL	0.6226 mL	0.7782 mL
100 mM	0.0156 mL	0.0778 mL	0.1556 mL	0.3113 mL	0.3891 mL