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    6-香叶草基柚皮素

    6-Geranylnaringenin

    6-香叶草基柚皮素
    产品编号 CFN92019
    CAS编号 97126-57-3
    分子式 = 分子量 C25H28O5 = 408.5
    产品纯度 >=98%
    物理属性 Cryst.
    化合物类型 Flavonoids
    植物来源 The herbs of Humulus lupulus
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    6-香叶草基柚皮素 CFN92019 97126-57-3 1mg QQ客服:2159513211
    6-香叶草基柚皮素 CFN92019 97126-57-3 5mg QQ客服:2159513211
    6-香叶草基柚皮素 CFN92019 97126-57-3 10mg QQ客服:2159513211
    6-香叶草基柚皮素 CFN92019 97126-57-3 20mg QQ客服:2159513211
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • Kyung Hee University (Korea)
  • University of East Anglia (United Kingdom)
  • Instytut Nawozów Sztucznych w Pu?awach (Poland)
  • Nicolaus Copernicus Uniwersity (Poland)
  • Imperial College London (United Kingdom)
  • National Hellenic Research Foundation (Greece)
  • Instituto Politécnico de Bragan?a (Portugal)
  • University of Stirling (United Kingdom)
  • Washington State University (USA)
  • University of Maryland School of Medicine (USA)
  • Technical University of Denmark (Denmark)
  • Universidad Veracuzana (Mexico)
  • Auburn University (USA)
  • Ain Shams University (Egypt)
  • More...
  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Tumour Biol.2015, 36(12):9385-93
  • Korean Journal of Pharmacognosy.2015, 46(4):352-364
  • Food Research International2016, 106-113
  • BMC Complement Altern Med.2016, 16:213
  • Biomed Chromatogr.2016, 30(10):1573-81
  • US20170000760 A12016, 42740
  • BMC Complement Altern Med.2017, 17(1):393
  • Cytotechnology.2017, 69(5):765-773
  • RSC Adv.2018, 32621-32636
  • J Sep Sci.2018, 41(11):2488-2497
  • Sci Rep.2018, 8:9267
  • Chemistry of Plant Materials.2019, 129-136
  • Aquaculture2019, 510:392-399
  • Plos One.2019, 15(2):e0220084
  • J of Ana. Chem.2019, 74(11):1113-1121
  • Biomed Chromatogr.2019, 8:e4774
  • Int J Biol Macromol.2020, 161:1230-1239.
  • Molecules.2020, 25(23):5609.
  • J Ethnopharmacol.2020, 260:112988.
  • Phytother Res.2020, 34(4):788-795.
  • Applied Biological Chemistry2020, 63:37.
  • Clin Exp Pharmacol Physiol.2020, doi: 10.1111
  • Inflammation.2021, doi: 10.1007
  • ...
  • 生物活性
    Description: 6-Geranylnaringenin is a natural product from Humulus lupulus.
    In vitro:
    J Clin Endocrinol Metab. 2000 Dec;85(12):4912-5.
    The endocrine activities of 8-prenylnaringenin and related hop (Humulus lupulus L.) flavonoids.[Pubmed: 11134162 ]
    The female flowers of the hop plant have long been used as a preservative and a flavoring agent in beer, but they are now being included in some herbal preparations for women for "breast enhancement."
    METHODS AND RESULTS:
    This study investigated the relative estrogenic, androgenic and progestogenic activities of the known phytoestrogen, 8-prenylnaringenin, and structurally related hop flavonoids. 6-Prenylnaringenin, 6,8-diprenylnaringenin and 8-geranylnaringenin exhibited some estrogenicity, but their potency was less than 1% of that of 8-prenylnaringenin. 8-Prenylnaringenin alone competed strongly with 17ss-estradiol for binding to both the alpha- and ss-estrogen receptors. None of the compounds (xanthohumol, isoxanthohumol, 8-prenyl-naringenin, 6-prenylnaringenin, 3'-geranylchalconaringenin, 6-Geranylnaringenin, 8-geranylnaringenin, 4'-O:-methyl-3'-prenylchalconaringenin and 6,8-diprenylnaringenin) nor polyphenolic hop extracts showed progestogenic or androgenic bioactivity.
    CONCLUSIONS:
    These results indicate that the endocrine properties of hops and hop products are due to the very high estrogenic activity of 8-prenylnaringenin and concern must be expressed about the unrestricted use of hops in herbal preparations for women.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 2.448 mL 12.2399 mL 24.4798 mL 48.9596 mL 61.1995 mL
    5 mM 0.4896 mL 2.448 mL 4.896 mL 9.7919 mL 12.2399 mL
    10 mM 0.2448 mL 1.224 mL 2.448 mL 4.896 mL 6.12 mL
    50 mM 0.049 mL 0.2448 mL 0.4896 mL 0.9792 mL 1.224 mL
    100 mM 0.0245 mL 0.1224 mL 0.2448 mL 0.4896 mL 0.612 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    甲基补骨脂黄酮; Bavachinin CFN98006 19879-30-2 C21H22O4 = 338.4 20mg QQ客服:1413575084
    5-Dehydroxyparatocarpin K; 5-Dehydroxyparatocarpin K CFN96117 124858-37-3 C20H18O4 = 322.4 5mg QQ客服:2932563308
    异补骨脂黄酮; Isobavachin CFN98400 31524-62-6 C20H20O4 = 324.4 20mg QQ客服:2159513211
    光甘草宁; Glabranin CFN98659 41983-91-9 C20H20O4 = 324.4 5mg QQ客服:2056216494
    二氢倒卵灰毛豆素; Dihydroobovatin CFN96075 104055-79-0 C20H20O4 = 324.4 5mg QQ客服:1457312923
    二氢柠檬黄烷酮 ; Dihydrocitflavanone CFN96562 70897-14-2 C20H20O5 = 340.38 5mg QQ客服:1457312923
    6-异戊二烯基柚皮素; 6-Prenylnaringenin CFN92017 68236-13-5 C20H20O5 = 340.4 10 mg QQ客服:1413575084
    6-异戊烯基樱花亭; 6-Prenylsakuranetin CFN92901 261776-61-8 C21H22O5 = 354.40 5mg QQ客服:2932563308
    8-异戊烯基柚皮素; 8-Prenylnaringenin CFN92016 53846-50-7 C20H20O5 = 340.4 10mg QQ客服:2159513211
    异黄腐醇; Isoxanthohumol CFN90768 70872-29-6 C21H22O5 = 354.4 20mg QQ客服:2056216494

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