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  • 4-羟基苯甲酸

    • 4-羟基苯甲酸

    4-Hydroxybenzoic acid

    4-羟基苯甲酸
    		产品编号 CFN97577
    CAS编号 99-96-7
    分子式 = 分子量 C7H6O3 = 138.1
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Phenols
    植物来源 The herbs of Rhodiola crenulata.
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    4-羟基苯甲酸 CFN97577 99-96-7 10mg QQ客服：3257982914
    4-羟基苯甲酸 CFN97577 99-96-7 20mg QQ客服：3257982914
    4-羟基苯甲酸 CFN97577 99-96-7 50mg QQ客服：3257982914
    4-羟基苯甲酸 CFN97577 99-96-7 100mg QQ客服：3257982914
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学，并且还在增涨
  • Istanbul University (Turkey)
  • University of Illinois at Chicago (USA)
  • Utah State University (USA)
  • Chulalongkorn University (Thailand)
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  • Heidelberg University (Germany)
  • Agricultural Research Organization (ARO) (Israel)
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  • Nicolaus Copernicus Uniwersity (Poland)
  • University of Hertfordshire (United Kingdom)
  • University of Wollongong (Australia)
  • Guangzhou Institutes of Biomedicine and Health (China)
  • More...
    • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Environ Toxicol.2019, 34(12):1354-1362
  • Phytother Res.2019, 33(5):1490-1500
  • Biorxiv2019, 10.1101
  • Institut Pasteur Korea2020, doi: 10.21203.
  • Phytother Res.2018, 32(12):2551-2559
  • Biomolecules.2020, 10(6):925.
  • Drug Des Devel Ther.2020, 14:5189-5204.
  • BMC Pharmacol Toxicol.2018, 19(1):5
  • Biochem Systematics and Ecology2017, 11-18
  • J Appl Biol Chem.2022, 65(4):pp.463-469.
  • Front Pharmacol.2022, 13:806869.
  • Bioorg Med Chem.2020, 28(12):115553.
  • VNU Journal of Science2023, No. 20.
  • Molecules.2020, 25(23):5556.
  • Process Biochemistry2019, 85:106-115
  • Int Immunopharmacol.2019, 71:361-371
  • Int Immunopharmacol.2021, 100:108073.
  • J Ethnopharmacol.2017, 198:205-213
  • Life Sci.2021, 286:120019.
  • J Nat Prod.2019, 82(4):1002-1008
  • Clin Exp Pharmacol Physiol.2020, doi: 10.1111
  • Environ Toxicol.2021, 36(9):1848-1856.
  • Dent Mater J.2020, 39(4):690-695
  • ...
    • 生物活性
    Description: 4-Hydroxybenzoic acid, also known as p-hydroxybenzoic acid (PHBA), is a phenolic derivative of benzoic acid and widely used in organic synthesis. 4-Hydroxybenzoic acid derivatives has potential to as pan-HDAC inhibitors with anticancer properties. 4-Hydroxybenzoic acid positively regulates the expression of gum cluster to promote EPS production in PXO99A; it can inhibit most gram-positive and some gram-negative bacteria, with an IC50 of 160 μg/mL.
    Targets: HDAC | Antifection
    In vitro:
    Biosci Biotechnol Biochem. 1998 Nov;62(11):2273-6.
    Antimicrobial activity of 4-hydroxybenzoic acid and trans 4-hydroxycinnamic acid isolated and identified from rice hull.[Pubmed: 9972252 ]

    METHODS AND RESULTS:
    Two antimicrobial substances in rice hull were isolated and identified as 4-hydroxybenzoic acid and trans 4-hydroxycinnamic acid by LC-MS, and 1H- and 13C-NMR. An evaluation of 50% inhibition of growth (IC50) revealed that the two substances had different inhibition profiles against various microorganisms.
    CONCLUSIONS:
    Most of the gram-positive and some gram-negative bacteria were sensitive to trans 4-hydroxycinnamic acid and 4-hydroxybenzoic acid at IC50 concentrations of 100-170 and 160 micrograms/ml, respectively.
    Int. J.Pharmaceut. Sci. Rev. Res., 2013, 22(2): 109-15.
    A Comprehensive Review on Biological activities of p-hydroxy benzoic acid and its derivatives.[Reference: WebLink]
    p-hydroxy benzoic acid (PHBA) is an organic chemical which can be obtained naturally as well as synthetically. The literature survey reveals its various biological properties viz. antimicrobial, antialgal, antimutagenic, antiestrogenic, hypoglycemic, anti-inflammatory, anti-platelet aggregating, nematicidal, antiviral, antioxidant etc. It is also reported to be used as preservative in many drugs, cosmetic products, pharmaceuticals, food and beverages. Some derivatives of 4-Hydroxybenzoic acid are found to possess direct action on Hbs molecules, inhibit acetic acid induced oedema and used in management of sickle cell disease.
    CONCLUSIONS:
    The present study will give comprehensive information of the biological activities of this p-hydroxy benzoic acid and its derivatives.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 7.2411 mL 36.2056 mL 72.4113 mL 144.8226 mL 181.0282 mL
    5 mM 1.4482 mL 7.2411 mL 14.4823 mL 28.9645 mL 36.2056 mL
    10 mM 0.7241 mL 3.6206 mL 7.2411 mL 14.4823 mL 18.1028 mL
    50 mM 0.1448 mL 0.7241 mL 1.4482 mL 2.8965 mL 3.6206 mL
    100 mM 0.0724 mL 0.3621 mL 0.7241 mL 1.4482 mL 1.8103 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    Cuneataside C; Cuneataside C CFN95368 871720-16-0 C19H28O12 = 448.4 10mg QQ客服：1457312923
    羟基酪醇醋酸酯; Hydroxytyrosol acetate CFN90927 69039-02-7 C10H12O4 = 196.2 20mg QQ客服：2056216494
    4-甲氧基苯甲酸 2-(4-羟基苯基)乙基酯; p-Hydroxyphenethyl anisate CFN96586 87932-34-1 C16H16O4 = 272.30 20mg QQ客服：215959384
    香草酸对羟基苯乙酯; p-Hydroxyphenethyl vanillate CFN89272 1539303-03-1 C16H16O5 = 288.29 5mg QQ客服：1457312923
    对羟基苯乙酮; 4'-Hydroxyacetophenone CFN97575 99-93-4 C8H8O2 = 136.2 20mg QQ客服：215959384
    4-羟基苯甲酰胺; 4-Hydroxybenzamide CFN97063 619-57-8 C7H7NO2 = 137.1 20mg QQ客服：215959384
    4-羟基苯甲酸; 4-Hydroxybenzoic acid CFN97577 99-96-7 C7H6O3 = 138.1 20mg QQ客服：1457312923
    尼泊金甲酯; Methyl 4-hydroxybenzoate CFN97571 99-76-3 C8H8O3 = 152.2 20mg QQ客服：215959384
    尼泊金乙酯; Ethylparaben CFN99320 120-47-8 C9H10O3 = 166.2 20mg QQ客服：1457312923
    对乙氧基苯甲酸; p-Ethoxybenzoic acid CFN92421 619-86-3 C9H10O3 = 166.2 20mg QQ客服：2056216494

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