3-Oxo-21alpha-methoxy-24,25,26,27-tetranortirucall-7-ene-23(21)-lactone

	产品编号	CFN96722
	CAS编号	1260173-73-6
	分子式 = 分子量	C₂₇H₄₀O₄ = 428.61
	产品纯度	>=98%
	物理属性	Powder
	化合物类型	Triterpenoids
	植物来源	The stem barks of Aphanamixis grandifolia.
ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用

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产品名称	产品编号	CAS编号	包装	QQ客服
3-Oxo-21alpha-methoxy-24,25,26,27-tetranortirucall-7-ene-23(21)-lactone	CFN96722	1260173-73-6	1mg	QQ客服：2056216494
3-Oxo-21alpha-methoxy-24,25,26,27-tetranortirucall-7-ene-23(21)-lactone	CFN96722	1260173-73-6	5mg	QQ客服：2056216494
3-Oxo-21alpha-methoxy-24,25,26,27-tetranortirucall-7-ene-23(21)-lactone	CFN96722	1260173-73-6	10mg	QQ客服：2056216494
3-Oxo-21alpha-methoxy-24,25,26,27-tetranortirucall-7-ene-23(21)-lactone	CFN96722	1260173-73-6	20mg	QQ客服：2056216494

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ChemFaces的产品在许多优秀和顶级科学期刊中被引用

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089

The Institute of Cancer Research (United Kingdom)

The Australian National University (Australia)

National Cancer Institute (USA)

University of South Australia (Australia)

Florida A&M University (USA)

Pennsylvania State University (USA)

Funda??o Universitária de Desenvolvimento (Brazil)

Leibniz-Institut für Pflanzenbiochemie (IPB) (Germany)

Celltrion Chemical Research Institute (Korea)

University of Helsinki (Finland)

Universiti Kebangsaan Malaysia (Malaysia)

Colorado State University (USA)

Johannes Gutenberg University Mainz (JGU) (Germany)

Regional Crop Research Institute (Korea)

More...

Description:

3-Oxo-21alpha-methoxy-24,25,26,27-tetranortirucall-7-ene-23(21)-lactone may show cytotoxic activities against five tumor cell lines (MCF-7, HeLa, HepG2, SGC-7901 and BGC-823).

In vitro:

Phytochemistry. 2010 Dec;71(17-18):2199-204.

Cytotoxic tirucallane C26 triterpenoids from the stem barks of Aphanamixis grandifolia.[Pubmed: 20851441 ]

METHODS AND RESULTS:
Five tirucallane type C(26) triterpenoids, accompanied by two known compounds, 3α-hydroxy-24,25,26,27-tetranortirucall-7-ene-23(21)-lactone and 3-oxo-24,25,26,27-tetranortirucall-7-ene-23(21)-lactone, were isolated from the stem barks of Aphanamixis grandifolia. Their structures were established mainly by means of a combination of 1D and 2D NMR spectroscopic and mass spectrometry techniques as 3α-hydroxyl-21α-methoxy-24,25,26,27-tetranortirucall-7-ene-23(21)-lactone, 3α-hydroxy-21β-methoxy-24,25,26,27-tetranortirucall-7-ene-23(21)-lactone,3-Oxo-21alpha-methoxy-24,25,26,27-tetranortirucall-7-ene-23(21)-lactone, 3-oxo-21β-methoxy-24,25,26,27-tetranortirucall-7-ene-23(21)-lactone, and 3-oxo-21α-ethoxy-24,25,26,27-tetranortirucall-7-ene-23(21)-lactone.
CONCLUSIONS:
All isolates were in vitro evaluated for their cytotoxic activities against five tumor cell lines (MCF-7, HeLa, HepG2, SGC-7901 and BGC-823).

产品名称	产品编号	CAS编号	分子式 = 分子量	位单	联系QQ
Bourjotinolone A; Bourjotinolone A	CFN97185	6985-35-9	C₃₀H₄₈O₄ = 472.7	5mg	QQ客服：1413575084
鬃毛酮; Hispidone	CFN97222	73891-72-2	C₃₀H₄₈O₄ = 472.7	5mg	QQ客服：1413575084
3-氧代-24,25,26,27-四去甲甘遂-7-烯-23(21)-内酯; 3-Oxo-24,25,26,27-tetranortirucall-7-en-23,21-olide	CFN97318	828935-47-3	C₂₆H₃₈O₃ = 398.6	5mg	QQ客服：3257982914
3-Oxo-21alpha-methoxy-24,25,26,27-tetranortirucall-7-ene-23(21)-lactone; 3-Oxo-21alpha-methoxy-24,25,26,27-tetranortirucall-7-ene-23(21)-lactone	CFN96722	1260173-73-6	C₂₇H₄₀O₄ = 428.61	5mg	QQ客服：2159513211
Laxiracemosin H ; Laxiracemosin H	CFN96601	1241871-28-2	C₂₆H₃₅NO₃ = 409.57	5mg	QQ客服：2159513211
苦楝萜酮内酯; Kulactone	CFN92976	22611-36-5	C₃₀H₄₄O₃ = 452.67	5mg	QQ客服：1457312923
3-Epimeliasenin B; 3-Epimeliasenin B	CFN97842	1222475-77-5	C₃₀H₄₄O₄ = 468.68	5mg	QQ客服：3257982914
Meliasenin B; Meliasenin B	CFN99339	1221262-77-6	C₃₀H₄₄O₄ = 468.7	5mg	QQ客服：2056216494
Sendanolactone; Sendanolactone	CFN97113	64929-59-5	C₃₀H₄₂O₄ = 466.7	5mg	QQ客服：2159513211
Deoxyflindissone ; Deoxyflindissone	CFN96965	107176-31-8	C₃₀H₄₆O₂ = 438.69	5mg	QQ客服：1457312923

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	2.3331 mL	11.6656 mL	23.3312 mL	46.6625 mL	58.3281 mL
5 mM	0.4666 mL	2.3331 mL	4.6662 mL	9.3325 mL	11.6656 mL
10 mM	0.2333 mL	1.1666 mL	2.3331 mL	4.6662 mL	5.8328 mL
50 mM	0.0467 mL	0.2333 mL	0.4666 mL	0.9332 mL	1.1666 mL
100 mM	0.0233 mL	0.1167 mL	0.2333 mL	0.4666 mL	0.5833 mL

3-Oxo-21alpha-methoxy-24,25,26,27-tetranortirucall-7-ene-23(21)-lactone

3-Oxo-21alpha-methoxy-24,25,26,27-tetranortirucall-7-ene-23(21)-lactone

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