| Biosci Biotechnol Biochem. 1998 Nov;62(11):2273-6. |
| Antimicrobial activity of 4-hydroxybenzoic acid and trans 4-hydroxycinnamic acid isolated and identified from rice hull.[Pubmed: 9972252] |
METHODS AND RESULTS:
Two antimicrobial substances in rice hull were isolated and identified as 4-hydroxybenzoic acid and trans-4-hydroxycinnamic acid by LC-MS, and 1H- and 13C-NMR. An evaluation of 50% inhibition of growth (IC50) revealed that the two substances had different inhibition profiles against various microorganisms.
CONCLUSIONS:
Most of the gram-positive and some gram-negative bacteria were sensitive to trans 4-hydroxycinnamic acid and 4-hydroxybenzoic acid at IC50 concentrations of 100-170 and 160 micrograms/ml, respectively. |
| J. Pharm. Res., 2013, 6(2):313-7. |
| In vitro evaluation of antioxidant and antibacterial activities of Rotula aquatica and Ancistrocladus heyneanus: Antioxidant and antimicrobial activity of medicinal plants.[Reference: WebLink] |
In the present study, the antioxidant and antimicrobial activities of the medicinal plants Rotula aquatica and Ancistrocladus heyneanus were evaluated.
METHODS AND RESULTS:
Antioxidant activity of the plant extracts was determined by total antioxidant capacity, ABTS and DPPH free radical scavenging activity, inhibitory activity toward β-carotene bleaching and lipid peroxidation, and DNA protection activity. Total phenolic and flavonoid contents were also estimated and the major phenolics present in the extract were identified by RP-HPLC. Significant free radical scavenging activity and marked antibacterial activity against food related bacteria Escherichia coli and Salmonella typhi were exhibited by the plant extracts used in the study.
CONCLUSIONS:
The work validates the ethnobotanical usage of the important medicinal plants R. aquatica and A. heyneanus. The plants used in the study possess significant antioxidant and antimicrobial property and have the potential for application in pharmaceutical and food industries as food supplements and natural preservatives. |
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.IF=36.216(2019)
Cell Metab. 2020 Mar 3;31(3):534-548.e5. doi: 10.1016/j.cmet.2020.01.002.IF=22.415(2019)
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.IF=14.548(2019)
ACS Nano. 2018 Apr 24;12(4): 3385-3396. doi: 10.1021/acsnano.7b08969.IF=13.903(2019)
Nature Plants. 2016 Dec 22;3: 16206. doi: 10.1038/nplants.2016.205.IF=13.297(2019)
Sci Adv. 2018 Oct 24;4(10): eaat6994. doi: 10.1126/sciadv.aat6994.IF=12.804(2019)
