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  • 中药标准品生产商,产品定制服务
  • Tectol

    Tectol

    Tectol
    产品编号 CFN91054
    CAS编号 2449-39-6
    分子式 = 分子量 C30H26O4 = 450.5
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Phenols
    植物来源 The herbs of Tectona grandis
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    Tectol CFN91054 2449-39-6 1mg QQ客服:1457312923
    Tectol CFN91054 2449-39-6 5mg QQ客服:1457312923
    Tectol CFN91054 2449-39-6 10mg QQ客服:1457312923
    Tectol CFN91054 2449-39-6 20mg QQ客服:1457312923
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    2. 只要有可能,产品溶解后,您应该在同一天应用于您的实验。 但是,如果您需要提前做预实验,或者需要全部溶解,我们建议您将溶液以等分试样的形式存放在-20℃的密封小瓶中。 通常,这些可用于长达两周。 使用前,打开样品瓶前,我们建议您将产品平衡至室温至少1小时。

    3. 需要更多关于溶解度,使用和处理的建议? 请发送电子邮件至:service@chemfaces.com
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • Monash University Malaysia (Malaysia)
  • University of Hawaii Cancer Center (USA)
  • Regional Crop Research Institute (Korea)
  • Washington State University (USA)
  • Nanjing University of Chinese Medicine (China)
  • Fraunhofer-Institut für Molekularbiologie und Angewandte ?kologie IME (Germany)
  • Florida International University (USA)
  • Harvard University (USA)
  • Universitas islam negeri Jakarta (Indonesia)
  • Korea Food Research Institute(KFRI) (Korea)
  • Nicolaus Copernicus Uniwersity (Poland)
  • Sri Sai Aditya Institute of Pharmaceutical Sciences and Research (India)
  • VIT University (India)
  • MTT Agrifood Research Finland (Finland)
  • More...
  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • SBRAS2016, 12
  • Biochem Biophys Res Commun.2020, 522(4):1052-1058
  • The Journal of Phytopharmacology2020, 9(1): 1-4
  • Sci Rep.2023, 13(1):7475.
  • Cancer Sci.2022, 113(4):1406-1416.
  • Academic J of Second Military Medical University2019, 40(1)
  • Kasetsart University2022, ethesis.1144.
  • The Korea Society of Pha.2014, 300-314
  • Drug Des Devel Ther.2020, 14:969-976.
  • Life (Basel).2021, 11(7):616.
  • Molecules.2022, 27(13):4227.
  • AMB Express2020. 10(1):126.
  • Front Chem.2023, 11:1245071.
  • Iranian Journal of Pharmaceutical Sciences2021, 17(2):25-36
  • Oncotarget.2015, 6(31):30831-49
  • Korean J Dent Mater2020, 47(2):63-70.
  • Front Plant Sci.2021, 12:673337.
  • Industrial Crops and Products2018, 353-362
  • Phytother Res.2019, 33(7):1784-1793
  • Legume Science2021, 3(4): e101.
  • SRM Institute of Sci&Tech2022, 34(1): 32-37
  • Food Chem.2019, 276:768-775
  • Cancer Manag Res.2019, 11:483-500
  • ...
  • 生物活性
    Description: Tectol has anti-plasmodial activity, it as a moderately active growth inhibitor with an IC50 3.44±0.20μM. It exhibited significant activity against human leukemia cell lines HL60 and CEM. Tectol may cause itchy dermatitis, the dermatitis appeared on the neck, upper legs, underarms, and trunk area.
    In vitro:
    J Nat Prod. 2001 Jun;64(6):792-5.
    Chemical constituents from Lippia sidoides and cytotoxic activity.[Pubmed: 11421746 ]

    METHODS AND RESULTS:
    Eleven known compounds and a new prenylated naphthoquinone, lippsidoquinone (13), were isolated from ethanol extracts of Lippia sidoides. Their structures were established by a combination of 1D and 2D NMR, IR, and EIMS spectral data analysis. The cytotoxic properties of compounds 3--13 were evaluated against HL60, SW1573, and CEM cell lines.
    CONCLUSIONS:
    Only tectol (6) and lippsidoquinone (13) exhibited significant activity against human leukemia cell lines HL60 and CEM.
    In vivo:
    Contact Dermatitis. 1987 Aug;17(2):115-6.
    Allergy to spermicidal lubricant in a contraceptive.[Pubmed: 3652700 ]

    METHODS AND RESULTS:
    Allergic contact dermatitis is reported in a patient using a condom with the spermicidal lubricant Tectol. A 36 year old female, with no history of dermatitis or pruritus of the vagina or vulva, experienced itchy dermatitis 24-48 hours after her partner used a Durex Top Safe contraceptive containing Tectol. The dermatitis appeared on the neck, upper legs, underarms, and trunk area. When another contraceptive was used Durex Featherlite (without Tectol), the patient experienced no problems.
    CONCLUSIONS:
    Patch tests concluded that the Tectol lubricant was the cause for the reaction in the patient. Transmission of the lubricant to the patient occurred when the patient's partner, after handling the contraceptive (Durex Top Safe) during intercourse, placed his hands on the patient's body. To which exact element of Tectol the patient was sensitized could not be determined as the patient refused further treatment.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 2.2198 mL 11.0988 mL 22.1976 mL 44.3951 mL 55.4939 mL
    5 mM 0.444 mL 2.2198 mL 4.4395 mL 8.879 mL 11.0988 mL
    10 mM 0.222 mL 1.1099 mL 2.2198 mL 4.4395 mL 5.5494 mL
    50 mM 0.0444 mL 0.222 mL 0.444 mL 0.8879 mL 1.1099 mL
    100 mM 0.0222 mL 0.111 mL 0.222 mL 0.444 mL 0.5549 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    滇杠柳素A; Forrestin A CFN99635 152175-76-3 C30H42O11 = 578.7 5mg QQ客服:2159513211
    雷帕霉素; Rapamycin (Sirolimus) CFN60038 53123-88-9 C51H79NO13 = 914.18 5mg QQ客服:2056216494
    粘毛黄芩素III 四乙酸酯; Viscidulin III tetraacetate CFN97545 96684-81-0 C25H22O12 = 514.4 5mg QQ客服:1413575084
    2,4-二羟基-6-甲基甲酸乙酯; Ethyl orsellinate CFN97773 2524-37-0 C10H12O4 = 196.20 20mg QQ客服:1413575084

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