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  • 紫杉平 B

    Taxuspine B

    紫杉平 B
    产品编号 CFN96630
    CAS编号 157414-05-6
    分子式 = 分子量 C35H42O10 = 622.71
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Diterpenoids
    植物来源 The stems of the Japanese yew Taxus cuspidata Sieb. et Zucc.
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    紫杉平 B CFN96630 157414-05-6 1mg QQ客服:1457312923
    紫杉平 B CFN96630 157414-05-6 5mg QQ客服:1457312923
    紫杉平 B CFN96630 157414-05-6 10mg QQ客服:1457312923
    紫杉平 B CFN96630 157414-05-6 20mg QQ客服:1457312923
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
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  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Korean J of Pharmacognosy2020, 51,49-54.
  • Oncotarget.2015, 6(31):30831-49
  • Int J Mol Sci.2022, 23(13):7115.
  • Molecules.2019, 24(1):E159
  • Molecules.2019, 24(23):E4303
  • Pharmacognosy Magazine2018, 14(56):418-424
  • Molecules.2021, 26(6):1738.
  • Pak J Pharm Sci.2023, 36(1):51-57.
  • Plant Biotechnology Reports 2021, 15:117-124.
  • Antioxidants (Basel).2019, 8(8):E307
  • Int J Mol Sci.2019, 20(3):E651
  • J Nat Med.2020, 74(3):550-560.
  • Phytomedicine.2018, 47:48-57
  • Molecules.2020, 25(23):5556.
  • Foods.2023, 12(12):2412.
  • Pak J Pharm Sci.2018, 31:311-315
  • Vietnam Journal of Food Control.2022, 5(3):pp.488-497.
  • J Nat Prod.2015, 78(6):1339-4
  • J Nat Med.2017, 71(2):380-388
  • J Microbiol Immunol Infect.2021, S1684-1182(21)00142-0.
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  • LWT2020, 126:109313
  • ...
  • 生物活性
    Description: Taxuspine B is a natural product from the Japanese yew Taxus cuspidata Sieb. et Zucc.
    In vitro:
    Tetrahedron, 1994, 50(25):7401-7416。
    Taxuspines A ~ C, new taxoids from Japanese yew Taxus cuspidata inhibiting drug transport activity of P-glycoprotein in multidrug-resistant cells[Reference: WebLink]

    METHODS AND RESULTS:
    Three new taxoids, taxuspine A, Taxuspine B, taxuspine C (1 ~ 3), possessing different skeletons from usual taxane diterpenoids consisting of a 6/8/6-membered ring system have been isolated together with known taxoids (4 ~ 12) from stems of the Japanese yew Taxus cuspidata Sieb. et Zucc. and the structures elucidated on the basis of spectroscopic data. Most of the taxoids increased cellular accumulation of vincristine in multidrug-resistant tumor cells, while taxol (12) did not show such an activity. The taxoids (1 ~ 11) showed no or weak cytotoxicity and among them, 2(Taxuspine B) and 6 reduced appreciably CaCI2-induced depolymerization of microtubules.
    CONCLUSIONS:
    These results suggest that some taxoids may be useful for overcoming multidrug resistance in tumor cells.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 1.6059 mL 8.0294 mL 16.0588 mL 32.1177 mL 40.1471 mL
    5 mM 0.3212 mL 1.6059 mL 3.2118 mL 6.4235 mL 8.0294 mL
    10 mM 0.1606 mL 0.8029 mL 1.6059 mL 3.2118 mL 4.0147 mL
    50 mM 0.0321 mL 0.1606 mL 0.3212 mL 0.6424 mL 0.8029 mL
    100 mM 0.0161 mL 0.0803 mL 0.1606 mL 0.3212 mL 0.4015 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    9-Deacetyl-9-benzoyl-10-debenzoyl-4beta,20-epoxytaxchinin A; 9-Deacetyl-9-benzoyl-10-debenzoyl-4beta,20-epoxytaxchinin A CFN89399 227011-48-5 C31H40O11 = 588.64 5mg QQ客服:3257982914
    9-Deacetyl-9-benzoyl-10-debenzoyltaxchinin A; 9-Deacetyl-9-benzoyl-10-debenzoyltaxchinin A CFN89393 172486-22-5 C31H40O10 = 572.64 5mg QQ客服:215959384
    紫杉平 W ; Taxuspine W CFN96629 181309-92-2 C26H36O9 = 492.57 5mg QQ客服:1413575084
    Taxin B ; Taxin B CFN96637 168109-52-2 C28H38O10 = 534.60 5mg QQ客服:1413575084
    2alpha,7beta,13alpha-Triacetoxy-5alpha-cinnamoyloxy-9beta-hydroxy-2(3->20)abeotaxa-4(20),11-dien-10-one; 2alpha,7beta,13alpha-Triacetoxy-5alpha-cinnamoyloxy-9beta-hydroxy-2(3->20)abeotaxa-4(20),11-dien-10-one CFN96903 322471-42-1 C35H42O10 = 622.71 5mg QQ客服:3257982914
    紫杉平 B; Taxuspine B CFN96630 157414-05-6 C35H42O10 = 622.71 5mg QQ客服:1413575084
    5,8,9,10,14-Pentaacetoxy-3-benzoyloxy-15-hydroxypepluane; 5,8,9,10,14-Pentaacetoxy-3-benzoyloxy-15-hydroxypepluane CFN98056 210108-91-1 C37H48O13 = 700.8 5mg QQ客服:215959384
    5,8,9,14-Tetraacetoxy-3-benzoyloxy-10,15-dihydroxypepluane; 5,8,9,14-Tetraacetoxy-3-benzoyloxy-10,15-dihydroxypepluane CFN89379 219916-77-5 C35H46O12 = 658.73 5mg QQ客服:1413575084
    Trigoxyphin A; Trigoxyphin A CFN96564 1236874-00-2 C34H34O9 = 586.63 5mg QQ客服:1457312923
    云南红豆杉酯甲; Taxayunnansin A CFN99643 153229-31-3 C35H44O13 = 672.7 5mg QQ客服:2056216494

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