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  • 2,6-二甲氧基酚/紫丁香醇

    Syringol

    2,6-二甲氧基酚/紫丁香醇
    产品编号 CFN92626
    CAS编号 91-10-1
    分子式 = 分子量 C8H10O3 = 154.2
    产品纯度 >=98%
    物理属性 Oil
    化合物类型 Phenols
    植物来源 The seeds of Artemisia herba-alba.
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    2,6-二甲氧基酚/紫丁香醇 CFN92626 91-10-1 10mg QQ客服:2056216494
    2,6-二甲氧基酚/紫丁香醇 CFN92626 91-10-1 20mg QQ客服:2056216494
    2,6-二甲氧基酚/紫丁香醇 CFN92626 91-10-1 50mg QQ客服:2056216494
    2,6-二甲氧基酚/紫丁香醇 CFN92626 91-10-1 100mg QQ客服:2056216494
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • Universite de Lille1 (France)
  • Monash University Sunway Campus (Malaysia)
  • Washington State University (USA)
  • Universidad Industrial de Santander (Colombia)
  • Centrum Menselijke Erfelijkheid (Belgium)
  • Semmelweis Unicersity (Hungary)
  • University of Wollongong (Australia)
  • Research Unit Molecular Epigenetics (MEG) (Germany)
  • Charles Sturt University (Denmark)
  • Chang Gung University (Taiwan)
  • Gyeongsang National University (Korea)
  • University of Oslo (Norway)
  • Florida International University (USA)
  • Sri Sai Aditya Institute of Pharmaceutical Sciences and Research (India)
  • More...
  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Mol Biol Rep.2022, doi: 10.1007
  • Cell Biochem Funct.2018, 36(6):303-311
  • Plants (Basel).2022, 11(21):2947.
  • Int J Mol Sci.2020, 21(19):7209.
  • Int. J. Mol. Sci.2022, 23(19), 11900.
  • Cardiovasc Toxicol.2019, 19(4):297-305
  • Food Chem.2019, 274:345-350
  • Plant Foods Hum Nutr.2020, 10.1007
  • Sci Rep.2018, 8(1)
  • The Journal of Internal Korean Medicine2015, 36(4):486-497
  • Microchemical Journal2023. 191:108938
  • Int Immunopharmacol.2021, 100:108073.
  • Res Rep Urol.2022, 14:313-326.
  • J Ethnopharmacol.2017, 198:91-97
  • BMC Complement Altern Med.2018, 18(1):221
  • Molecules.2020, 25(23):5609.
  • SCOPUS.2020, 836-847.
  • Genes (Basel).2021, 12(7):1024.
  • Biochem Biophys Res Commun.2020, 530(1):4-9.
  • Sci Rep.2015, 5:13194
  • Evid Based Complement Alternat Med.2016, 2016:4357656
  • Toxicol Appl Pharmacol.2021, 427:115668.
  • Viruses.2021, 13(11):2118.
  • ...
  • 生物活性
    Description: Syringol and phenol have modifying effect on NMOR formation in vivo to be similar, the effect of food on NMOR levels in blood is more important than that of the modifiers.
    In vivo:
    Carcinogenesis. 1986 Jun;7(6):867-70.
    Effects of phenol and 2,6-dimethoxyphenol (syringol) on in vivo formation of N-nitrosomorpholine in rats.[Pubmed: 3708751]
    We determined the effects of phenol and 2,6-dimethoxyphenol (Syringol) on N-nitrosomorpholine (NMOR) formation in rats given morpholine and nitrite by gavage.
    METHODS AND RESULTS:
    At 30 min post-gavage the recovery (from the stomach, duodenum and blood) of 564 micrograms NMOR was six times higher when administered to rats by gavage with 2 g of semipurified diet (SPD) than when given without food. Rats were gavaged with 12 mg each of morpholine, one of the modifiers and nitrite and examined 30 min later. Syringol decreased the amount of NMOR in both the stomach and blood by 89%, while phenol had no effect. We compared these results with those obtained with ascorbic acid and thiocyanate. The effect of ascorbic acid was similar to that of Syringol. However, thiocyanate increased the amount of NMOR in the stomach and blood 2.7- and 4-fold, respectively. When 2 g of SPD was administered to rats by gavage, together with the precursors, Syringol and ascorbic acid blocked NMOR formation in the stomach by 58 and 45%, respectively, and thiocyanate enhanced the yield 1.5-fold. The effect of phenol was not significant for the stomach and blood and that of the other modifiers was not significant for blood. Administration of the reactants together with food decreased the NMOR level in blood 155-fold relative to controls (no food), suggesting that food decreased the absorption rate over a 30-min period.
    CONCLUSIONS:
    These results demonstrate the modifying effect of phenol and Syringol on NMOR formation in vivo to be similar to that observed in a previous in vitro study, and show that the effect of food on NMOR levels in blood was more important than that of the modifiers.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 6.4851 mL 32.4254 mL 64.8508 mL 129.7017 mL 162.1271 mL
    5 mM 1.297 mL 6.4851 mL 12.9702 mL 25.9403 mL 32.4254 mL
    10 mM 0.6485 mL 3.2425 mL 6.4851 mL 12.9702 mL 16.2127 mL
    50 mM 0.1297 mL 0.6485 mL 1.297 mL 2.594 mL 3.2425 mL
    100 mM 0.0649 mL 0.3243 mL 0.6485 mL 1.297 mL 1.6213 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    1,2,3-苯三酚; Pyrogallol CFN97443 87-66-1 C6H6O3 = 126.1 20mg QQ客服:2056216494
    2,6-二甲氧基酚/紫丁香醇; Syringol CFN92626 91-10-1 C8H10O3 = 154.2 20mg QQ客服:1457312923
    3,5-二甲氧基-4-羟基苯基 beta-D-葡萄糖苷; Koaburaside CFN98654 41653-73-0 C14H20O9 = 332.3 5mg QQ客服:1413575084
    3,4,5-三甲氧基苯酚; Antiarol CFN97105 642-71-7 C9H12O4 = 184.2 20mg QQ客服:2056216494
    3,4,5-三甲氧基苯基 beta-D-吡喃葡萄糖苷; Koaburaside monomethyl ether CFN98650 41514-64-1 C15H22O9 = 346.3 10 mg QQ客服:1413575084
    3,4,5-三甲氧基苯酚芦丁糖甙; Antiarol rutinoside CFN98298 261351-23-9 C21H32O13 = 492.5 5mg QQ客服:2159513211
    3,4,5-三甲氧基苯基6-O-D-芹糖-beta-D-呋喃糖基-beta-D-葡萄糖苷; Kelampayoside A CFN97441 87562-76-3 C20H30O13 = 478.5 5mg QQ客服:1457312923

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