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  • Strychnistenolide

    Strychnistenolide

    Strychnistenolide
    产品编号 CFN91933
    CAS编号 332372-09-5
    分子式 = 分子量 C15H18O4 = 262.30
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Sesquiterpenoids
    植物来源 The roots of Lindera aggregata
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    Strychnistenolide CFN91933 332372-09-5 1mg QQ客服:3257982914
    Strychnistenolide CFN91933 332372-09-5 5mg QQ客服:3257982914
    Strychnistenolide CFN91933 332372-09-5 10mg QQ客服:3257982914
    Strychnistenolide CFN91933 332372-09-5 20mg QQ客服:3257982914
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • Sanford Burnham Medical Research Institute (USA)
  • University of Hawaii Cancer Center (USA)
  • Funda??o Universitária de Desenvolvimento (Brazil)
  • University of Hertfordshire (United Kingdom)
  • Leibniz Institute of Plant Biochemistry (Germany)
  • University of Parma (Italy)
  • Hamdard University (India)
  • Amity University (India)
  • University of Pretoria (South Africa)
  • Instituto Politécnico de Bragan?a (Portugal)
  • Heidelberg University (Germany)
  • The Institute of Cancer Research (United Kingdom)
  • John Innes Centre (United Kingdom)
  • Istanbul University (Turkey)
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  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • J Sci Food Agric.2023, 103(1):213-220.
  • J Herbmed Pharmacol.2018, 7(4):280-286
  • Histol Histopathol.2022, 18518.
  • Chem Pharm Bull (Tokyo).2019, 67(11):1242-1247
  • Natural Product Communications2020, doi: 10.1177.
  • Metabolites.2020, 10(11):440.
  • Molecules.2019, 24(16):E2985
  • Nanjing University of Chinese Medicine2022, 345930.
  • Oncol Rep.2021, 46(2):166.
  • Food Res Int.2022, 157:111207.
  • Antioxidants (Basel).2021, 10(10):1638.
  • Molecules.2020, 25(9):2111.
  • Free Radic Biol Med.2016, 97:307-319
  • Viruses2023, 15(6), 1377
  • J Agric Food Chem.2021, 69(11):3496-3510.
  • Front Pharmacol.2018, 9:236
  • Front Nutr.2021, 8: 687851.
  • Biomed Pharmacother.2020, 125:109784.
  • BMC Plant Biol.2018, 18(1):122
  • J Food Biochem.2020, 44(6):e13198.
  • J Ethnopharmacol.2016, 192:370-381
  • Cardiovasc Toxicol.2021, 21(11):947-963.
  • Biomolecules.2023, 13(2):227.
  • ...
  • 生物活性
    Description: Reference standards.
    In vitro:
    J Nat Prod. 2009 Aug;72(8):1497-501.
    Sesquiterpene lactones from the root tubers of Lindera aggregata.[Pubmed: 19639966 ]

    METHODS AND RESULTS:
    Phytochemical investigation of the root tubers of Lindera aggregata resulted in the isolation of five new sesquiterpene lactones, linderagalactones A-E (1-5), along with eight known sesquiterpenoids, 3-eudesmene-1beta,11-diol, hydroxylindestenolide, Strychnistenolide, hydroxyisogermafurenolide, atractylenolide III, linderane, neolinderalactone, and linderalactone. The structures and relative configurations of 1-5 were determined by spectroscopic methods, especially HRESIMS and 2D NMR techniques. The absolute configurations of 1-4 were defined by comparison of quantum chemical TDDFT calculated and experimental ECD spectra.
    CONCLUSIONS:
    Linderagalactone A (1) is a halogenated sesquiterpene lactone possessing a unique rearranged carbon skeleton. Linderagalactone E (5), linderane, hydroxylindestenolide, and linderalactone showed hepatoprotective activity against H2O2-induced oxidative damages on HepG2 cells with EC(50) values of 67.5, 167.0, 42.4, and 98.0 microM, respectively.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 3.8124 mL 19.0621 mL 38.1243 mL 76.2486 mL 95.3107 mL
    5 mM 0.7625 mL 3.8124 mL 7.6249 mL 15.2497 mL 19.0621 mL
    10 mM 0.3812 mL 1.9062 mL 3.8124 mL 7.6249 mL 9.5311 mL
    50 mM 0.0762 mL 0.3812 mL 0.7625 mL 1.525 mL 1.9062 mL
    100 mM 0.0381 mL 0.1906 mL 0.3812 mL 0.7625 mL 0.9531 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    莪术呋喃烯酮; Curzerenone CFN92027 20493-56-5 C15H18O2 = 230.3 20mg QQ客服:215959384
    表莪术呋喃烯酮; Epicurzerenone CFN92613 20085-85-2 C15H18O2 = 230.3 5mg QQ客服:2056216494
    异乌药内酯; Isolinderalactone CFN99762 957-66-4 C15H16O3 = 244.29 10mg QQ客服:2056216494
    苍术酮; Atractylone CFN92066 6989-21-5 C15H20O = 216.3 5mg QQ客服:215959384
    乌药醇; Linderene CFN90639 26146-27-0 C15H18O2 = 230.3 10mg QQ客服:2159513211
    乌药醇乙酸酯; Linderene acetate CFN91930 26146-28-1 C17H20O3 = 272.34 5mg QQ客服:2159513211
    Strychnistenolide; Strychnistenolide CFN91933 332372-09-5 C15H18O4 = 262.30 5mg QQ客服:1457312923
    8beta,9alpha-Dihydroxylindan-4(5),7(11)-dien-8alpha,12-olide; 8beta,9alpha-Dihydroxylindan-4(5),7(11)-dien-8alpha,12-olide CFN91948 956707-04-3 C15H18O4 = 262.30 5mg QQ客服:215959384
    姜黄醇酮; Curcolone CFN92651 17015-43-9 C15H18O3 = 246.3 5mg QQ客服:1413575084
    Zedoarofuran; Zedoarofuran CFN92619 213833-34-2 C15H20O4 = 264.3 5mg QQ客服:2056216494

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