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  • Randaiol

    Randaiol

    Randaiol
    产品编号 CFN96098
    CAS编号 87562-14-9
    分子式 = 分子量 C15H14O3 = 242.3
    产品纯度 >=98%
    物理属性 Oil
    化合物类型 Lignans
    植物来源 The barks of Magnolia hypoleuca
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    Randaiol CFN96098 87562-14-9 1mg QQ客服:2159513211
    Randaiol CFN96098 87562-14-9 5mg QQ客服:2159513211
    Randaiol CFN96098 87562-14-9 10mg QQ客服:2159513211
    Randaiol CFN96098 87562-14-9 20mg QQ客服:2159513211
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • Tokyo Woman's Christian University (Japan)
  • Universidade Católica Portuguesa (Portugal)
  • Calcutta University (India)
  • Monash University Malaysia (Malaysia)
  • Institute of Chinese Materia Medica (China)
  • Medical University of Gdansk (Poland)
  • Harvard University (USA)
  • Sant Gadge Baba Amravati University (India)
  • Mahatma Gandhi University (India)
  • Uniwersytet Jagielloński w Krakowie (Poland)
  • The Vancouver Prostate Centre (VPC) (Canada)
  • Agricultural Research Organization (ARO) (Israel)
  • Macau University of Science and Technology (China)
  • University of East Anglia (United Kingdom)
  • More...
  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Foods.2021, 10(12):2929.
  • Biol Pharm Bull.2017, 40(6):797-806
  • Pharmacognosy Journal.2020, 12(2), p232-235.
  • Analytical Letters.2020, doi 10.1008
  • Food Bioscience2022, 50:102187.
  • Cosmetics2021, 8(3),91.
  • Asian J Beauty Cosmetol2021, 19(1): 57-64.
  • Evid Based Complement Alternat Med.2020, 2020:2584783.
  • Evid Based Complement Alternat Med.2021, 2021:8847358.
  • Antioxidants (Basel).2020, 9(4):284.
  • Daru.2022, 30(2):273-288.
  • Front Endocrinol (Lausanne).2020, 11:568436.
  • Eur J Pharmacol.2018, 832:96-103
  • Biochem Biophys Res Commun.2020, 527(4):889-895.
  • Molecules.2021, 26(18):5665.
  • Front Pharmacol.2019, 10:1226
  • Agronomy2020, 10(10),1489
  • Phytochemistry Letters2015, 243-247
  • Journal of Food and Drug Analysis2023, 31(3), 9.
  • Food Chemistry2023, 137837.
  • Molecules.2017, 22(2)
  • Mol Cell.2017, 68(4):673-685
  • Cardiovasc Toxicol.2021, 21(11):947-963.
  • ...
  • 生物活性
    Description: Randaiol is a natural product from Magnolia hypoleuca.
    In vitro:
    Planta Medica, 2011 , 77 (12):42.
    New biphenyl derivatives and anti-inflammatory constituents from the stem bark of Magnolia officinalis[Reference: WebLink]
    The stem bark of Magnolia officinalis Rehd. et Wils. (Magnoliaceae) has been used as a traditional medicine for the treatment of gastrointestinal disorders, bronchitis, and emphysema, in China, Taiwan, Japan, and Korea [1]. Chemical studies have revealed a variety of neo-lignans and alkaloids as constituents of this plant. Many of these compounds exhibit central depressant effect, muscle relaxation, and antigastric ulcer, antibacterial, antiallergic, vasorelaxant, and neurotrophic activities.
    METHODS AND RESULTS:
    Investigation on EtOAc-soluble fraction of the stem bark of M. officinalis has led to the isolation of three new biphenyls, 5-allyl-5'-(1-hydroxyallyloxy)biphenyl-2,2-diol (1), 5,5'-diallyl-2'-(allyloxy)biphenyl-2-ol (2), and 5,5'-diallyl-2'-(3-methylbut-2-enyloxy)biphenyl-2-ol (3), together with 12 known compounds, including four neolignans, magnolol (4), honokiol (5), (-)-monoterpenylmagnolol (6), and randainal (7), two norlignans, magnaldehyde D (8) and Randaiol (9), and six steroids, β-sitostenone (10), stigmasta-4,22-dien-3-one (11), β-sitosterol (12), stigmasterol (13), 3β-hydroxystigmast-5-en-7-one (14), and 3β-hydroxystigmasta-5,22-dien-7-one (15). The structure of new compounds (1-3) were determined through spectroscopic and MS analyses. Among the isolates, magnolol (4) and honokiol (5) exhibited potent inhibition against fMLP-induced superoxide production with IC50 values of 4.42±0.24 and 0.68±0.20μg/mL, respectively. In addition, magnolol (4) inhibited fMLP/CB-induced elastase release with an IC50 values of 1.45±0.20μg/mL.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 4.1271 mL 20.6356 mL 41.2712 mL 82.5423 mL 103.1779 mL
    5 mM 0.8254 mL 4.1271 mL 8.2542 mL 16.5085 mL 20.6356 mL
    10 mM 0.4127 mL 2.0636 mL 4.1271 mL 8.2542 mL 10.3178 mL
    50 mM 0.0825 mL 0.4127 mL 0.8254 mL 1.6508 mL 2.0636 mL
    100 mM 0.0413 mL 0.2064 mL 0.4127 mL 0.8254 mL 1.0318 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    厚朴木酚素A; Magnolignan A CFN96188 93673-81-5 C18H20O4 = 300.4 10mg QQ客服:215959384
    厚朴木酚素C; Magnolignan C CFN96189 93697-42-8 C18H20O4 = 300.4 10mg QQ客服:2159513211
    (1S,2S)-threo-Honokitriol; (1S,2S)-threo-Honokitriol CFN95076 1099687-80-5 C18H20O5 = 316.4 5mg QQ客服:3257982914
    厚朴醛B; Magnaldehyde B CFN95075 92829-72-6 C18H16O3 = 280.3 5mg QQ客服:3257982914
    厚朴醛D; Magnaldehyde D CFN96172 93753-33-4 C16H14O3 = 254.3 5mg QQ客服:215959384
    四氢厚朴酚; Tetrahydromagnolol CFN91033 20601-85-8 C18H22O2 = 270.4 20mg QQ客服:1457312923
    厚朴酚; Magnolol CFN98872 528-43-8 C18H18O2 = 266.3 20mg QQ客服:1457312923
    和厚朴酚; Honokiol CFN99902 35354-74-6 C18H18O2 = 266.34 20mg QQ客服:215959384
    4'-O-甲基和厚朴酚; 4'-O-Methylhonokiol CFN91498 68592-15-4 C19H20O2 = 280.4 5mg QQ客服:3257982914
    2-O-甲基和厚朴酚; 2-O-Methylhonokiol CFN91499 68592-19-8 C19H20O2 = 280.4 5mg QQ客服:2056216494

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