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  • Praeroside II

    Praeroside II

    Praeroside II
    产品编号 CFN96695
    CAS编号 86940-46-7
    分子式 = 分子量 C20H24O10 = 424.40
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Coumarins
    植物来源 The roots of Angelica furcijuga.
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    Praeroside II CFN96695 86940-46-7 1mg QQ客服:2159513211
    Praeroside II CFN96695 86940-46-7 5mg QQ客服:2159513211
    Praeroside II CFN96695 86940-46-7 10mg QQ客服:2159513211
    Praeroside II CFN96695 86940-46-7 20mg QQ客服:2159513211
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • VIB Department of Plant Systems Biology, UGent (PSB) (Belgium)
  • Julius Kühn-Institut (Germany)
  • University of Leipzig (Germany)
  • Centralised Purchases Unit (CPU), B.I.T.S (India)
  • Melbourne University (Australia)
  • Sri Sai Aditya Institute of Pharmaceutical Sciences and Research (India)
  • Nicolaus Copernicus Uniwersity (Poland)
  • Complutense University of Madrid (Spain)
  • Instytut Nawozów Sztucznych w Pu?awach (Poland)
  • The Ohio State University (USA)
  • Amity University (India)
  • Sri Ramachandra University (India)
  • Worcester Polytechnic Institute (USA)
  • Sant Gadge Baba Amravati University (India)
  • More...
  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Life (Basel).2022, 12(10):1630.
  • Pharmacognosy Journal2019, 11(2): 369-373
  • Lab Chip.2018, 18(6):971-978
  • Antioxidants (Basel).2022, 11(8):1471.
  • BMC Complement Altern Med.2019, 19(1):367
  • Turk J Med Sci.2023 53: 1312-1320.
  • Phytother Res.2019, 33(3):676-689
  • Food Funct.2021, 12(4):1469-1481.
  • J Hematol Oncol.2018, 11(1):112
  • J.of Traditional&Complementary Med.2022, 10.1016:j.jtcme.
  • Front Pharmacol.2020, 11:251.
  • Plos One.2019, 15(2):e0220084
  • Anticancer Res.2014, 34(7):3505-9
  • Int J Mol Sci.2018, 19(9):E2825
  • Mol Cell.2017, 68(4):673-685
  • Journal of Plant Growth Regulation2022, 10705-2.
  • Oncotarget.2017, 9(3):4161-4172
  • Appl Biochem Biotechnol.2022, s12010-022-04166-2.
  • Biology (Basel).2020, 9(11):363.
  • J Ethnopharmacol.2019, 244:112074
  • Arch Pharm Res.2015, 38(6):1080-9
  • Sci Rep.2019, 9:19059
  • Applied Biological Chemistry 2021, 64(75)
  • ...
  • 生物活性
    Description: Praeroside II shows inhibitory activity of NO production in macrophages.
    Targets: NO
    In vitro:
    Bioorg Med Chem Lett. 1998 Aug 18;8(16):2191-6.
    Hepatoprotective and nitric oxide production inhibitory activities of coumarin and polyacetylene constituents from the roots of Angelica furcijuga.[Pubmed: 9873511]
    The methanolic extract from the roots of Angelica furcijuga KITAGAWA was found to exhibit protective effects on liver injury induced by D-galactosamine (D-GalN) and lipopolysaccharide (LPS).
    METHODS AND RESULTS:
    From the methanolic extract, seventeen coumarins, two phenylpropanoids, and two polyacetylenes were isolated and examined their in vitro and in vivo hepatoprotective effects and inhibitory activity of NO production in macrophages. A acylated khellactone, isoepoxypteryxin, showed protective activity against D-GalN-induced cytotoxicity in primary cultured rat hepatocytes. On the other hand, six acylated khellactones (hyuganins A, B, C, and D, anomalin, isopteryxin) and two polyacetylenes [(-)-falcarinol and falcarindiol] strongly inhibited NO production induced by LPS in cultured mouse peritoneal macrophages, and also other acylated khellactones (isoepoxypteryxin, pteryxin, and suksdorfin) and a coumarin glycosides (Praeroside II) were found to show the activity.
    CONCLUSIONS:
    By comparison of the inhibitory activities for acylated khellactones with those for other coumarins, acyl groups were found to be essential to exerting potent activity.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 2.3563 mL 11.7813 mL 23.5627 mL 47.1254 mL 58.9067 mL
    5 mM 0.4713 mL 2.3563 mL 4.7125 mL 9.4251 mL 11.7813 mL
    10 mM 0.2356 mL 1.1781 mL 2.3563 mL 4.7125 mL 5.8907 mL
    50 mM 0.0471 mL 0.2356 mL 0.4713 mL 0.9425 mL 1.1781 mL
    100 mM 0.0236 mL 0.1178 mL 0.2356 mL 0.4713 mL 0.5891 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    白花前胡丙素; Praeruptorin C CFN98143 72463-77-5 C24H28O7 = 428.48 20mg QQ客服:3257982914
    (-)-白花前胡素 B; (-)-Praeruptorin B CFN89387 4970-26-7 C24H26O7 = 426.45 5mg QQ客服:1413575084
    丝立尼亭; Selinidin CFN90570 19427-82-8 C19H20O5 = 328.4 5mg QQ客服:3257982914
    前胡香豆精E; Qianhucoumarin E CFN92597 156041-02-0 C19H18O6 = 342.4 5mg QQ客服:215959384
    前胡香豆精 A; Qianhucoumarin A CFN92709 150135-35-6 C19H20O6 = 344.4 5mg QQ客服:1457312923
    顺式-(+)-凯林内酯; Khellactone CFN96394 24144-61-4 C14H14O5 = 262.3 5mg QQ客服:3257982914
    顺式-甲基凯诺内酯; cis-Methylkhellactone CFN89413 20107-13-5 C15H16O5 = 276.28 5mg QQ客服:2159513211
    Praeroside II; Praeroside II CFN96695 86940-46-7 C20H24O10 = 424.40 5mg QQ客服:2159513211
    (+)-沙米丁; Samidin CFN96375 477-33-8 C21H22O7 = 386.4 5mg QQ客服:2056216494
    Hyuganin D; Hyuganin D CFN89402 77331-76-1 C20H22O7 = 374.38 5mg QQ客服:2159513211

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