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  • 鸡蛋花甙

    Plumieride

    鸡蛋花甙
    产品编号 CFN98815
    CAS编号 511-89-7
    分子式 = 分子量 C21H26O12 = 470.4
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Iridoids
    植物来源 The herbs of Himatanthus fallax.
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    鸡蛋花甙 CFN98815 511-89-7 1mg QQ客服:2056216494
    鸡蛋花甙 CFN98815 511-89-7 5mg QQ客服:2056216494
    鸡蛋花甙 CFN98815 511-89-7 10mg QQ客服:2056216494
    鸡蛋花甙 CFN98815 511-89-7 20mg QQ客服:2056216494
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • University of Canterbury (New Zealand)
  • Guangzhou Institutes of Biomedicine and Health (China)
  • Chinese University of Hong Kong (China)
  • Periyar University (India)
  • Sri Sai Aditya Institute of Pharmaceutical Sciences and Research (India)
  • Sanford Burnham Medical Research Institute (USA)
  • VIB Department of Plant Systems Biology, UGent (PSB) (Belgium)
  • Centrum Menselijke Erfelijkheid (Belgium)
  • National Cancer Center Research Institute (Japan)
  • Lodz University of Technology (Poland)
  • University of Indonesia (Indonesia)
  • University of Perugia (Italy)
  • Washington State University (USA)
  • Wroclaw Medical University (Poland)
  • More...
  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Plant Methods.2017, 13:108
  • Mol Cells.2018, 41(8):771-780
  • J Chromatogr A.2022, 1685:463640.
  • Molecules.2022, 27(22):7887.
  • Bioengineering2023, 10(10), 1113.
  • Plos One.2019, 15(2):e0220084
  • Food Chem.2019, 276:768-775
  • Front Immunol.2020, 11:598556.
  • Sci Rep. 2017, 12953(7)
  • Microchemical Journal2024: 196:109676.
  • Int J Biol Macromol.2020, 161:1230-1239.
  • Exp Mol Med.2020, 52(4):629-642.
  • Bioorg Med Chem.2018, 26(14):4201-4208
  • J Cell Mol Med.2023, 27(11):1592-1602.
  • Front Aging Neurosci.2019, 11:230
  • Korean Journal of Pharmacognosy2018, 49(4):349-361
  • Journal of Ginseng Research2022, j.jgr.2022.09.005.
  • Antioxidants (Basel).2019, 8(8):E307
  • Front Pharmacol.2021, 12:744624.
  • Theranostics.2023, 13(9):3103-3116.
  • Integr Med Res.2017, 6(4):395-403
  • Institute of Food Science & Technology2021, 56(11).
  • Food Chem.2021, 377:131976.
  • ...
  • 生物活性
    Description: Plumieride has plant growth inhibiting properties, it shows strong fungitoxicity against some dermatophytes causing dermatomycosis to animals and human beings. Plumieride also has antioxidant , and immunomodulatory activities.
    Targets: Immunology & Inflammation related
    In vitro:
    J Org Chem. 2004 Sep 17;69(19):6165-72.
    Structural modifications of plumieride isolated from Plumeria bicolor and the effect of these modifications on in vitro anticancer activity.[Pubmed: 15357574]
    Plumieride was isolated as one of the major components from the biologically active methanolic extract of the bark of Plumeria bicolor (family Apocynaceae). For investigating the effect of substituents on cytotoxic activity it was modified into a series of compounds.
    METHODS AND RESULTS:
    Replacing the methyl ester functionality of Plumieride with alkyl amides of variable carbon units improved the cytotoxic activity, and a correlation between overall lipophilicity and cytotoxic activity was observed. In Plumieride, the glucose moiety was converted into a di- and trisaccharide by following the protection and deprotection approach, and the resulting compounds produced enhanced cytotoxicity. However, these compounds were found to be less effective than plumeiride containing a dodecyl (12 carbon units) amide group.
    CONCLUSIONS:
    Among all of the derivatives, the naturally occurring Plumieride showed the least cytotoxicity (50% cell kill = 49.5 microg/mL), and the dodecyl amide analogue of Plumieridepentaacetate produced the best efficacy (50% cell kill = 11.8 microg/mL). The di- and trisaccharide analogues were found to be slightly less effective than the dodecyl derivative (50% cell kill = 15-17 microg/mL). The in vitro cytotoxicity of the Plumieride analogues was determined in radiation-induced fibrosarcoma (RIF) tumor cells.
    Phytother Res. 2002 Jun;16(4):393-4.
    Plumieride from Allamanda cathartica as an antidermatophytic agent.[Pubmed: 12112301 ]

    METHODS AND RESULTS:
    Plumieride has been isolated as an active principle of the leaves of Allamanda cathartica. It showed strong fungitoxicity against some dermatophytes causing dermatomycosis to animals and human beings. It exhibited a noncytotoxic nature against a P(388) mouse leukaemia cell line.
    Phytochemistry, 1979, 18(8):1399-400.
    Plant growth inhibiting properties of plumieride from Plumeria obtusifolia.[Reference: WebLink]

    METHODS AND RESULTS:
    Plant growth inhibiting properties of plumieride from Plumeria obtusifolia.
    J&k State Science Congress, University of Jammu, Jammu. 2005.
    Immunomodulatory activity of Plumieride, an iridoid glucoside from Plumieria acutifolia leaves.[Reference: WebLink]

    METHODS AND RESULTS:
    Immunomodulatory activity of Plumieride, an iridoid glucoside from Plumieria acutifolia leaves.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 2.1259 mL 10.6293 mL 21.2585 mL 42.517 mL 53.1463 mL
    5 mM 0.4252 mL 2.1259 mL 4.2517 mL 8.5034 mL 10.6293 mL
    10 mM 0.2126 mL 1.0629 mL 2.1259 mL 4.2517 mL 5.3146 mL
    50 mM 0.0425 mL 0.2126 mL 0.4252 mL 0.8503 mL 1.0629 mL
    100 mM 0.0213 mL 0.1063 mL 0.2126 mL 0.4252 mL 0.5315 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    β-二氢鸡蛋花素酸 ; beta-Dihydroplumericinic acid CFN97002 59204-61-4 C14H14O6 = 278.3 5mg QQ客服:2056216494
    黄蝉花辛, 黄蝉花内酯; Allamandicin CFN97731 51838-83-6 C15H16O7 = 308.29 5mg QQ客服:1457312923
    15-去甲基鸡蛋花苷; 15-Demethylplumieride CFN99411 132586-69-7 C20H24O12 = 456.4 5mg QQ客服:3257982914
    鸡蛋花甙; Plumieride CFN98815 511-89-7 C21H26O12 = 470.4 5mg QQ客服:1413575084
    13-O-对香豆酰鸡蛋花甙; 13-O-p-Coumaroylplumieride CFN97278 80416-52-0 C30H32O14 = 616.6 5mg QQ客服:3257982914
    原鸡蛋花素A; Protoplumericin A CFN97673 80396-57-2 C36H42O19 = 778.72 5mg QQ客服:2056216494

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