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  • Pinocembrin 7-O-(3''-galloyl-4'',6''-(S)-hexahydroxydiphenoyl)-β-D-glucose

    Pinocembrin 7-O-(3''-galloyl-4'',6''-(S)-hexahydroxydiphenoyl)-beta-D-glucose

    Pinocembrin 7-O-(3''-galloyl-4'',6''-(S)-hexahydroxydiphenoyl)-β-D-glucose
    产品编号 CFN90881
    CAS编号 205370-59-8
    分子式 = 分子量 C42H32O21 = 872.7
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Flavonoids
    植物来源 The herbs of Lindera strychnifolia
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    Pinocembrin 7-O-(3''-galloyl-4'',6''-(S)-hexahydroxydiphenoyl)-β-D-glucose CFN90881 205370-59-8 10mg QQ客服:2056216494
    Pinocembrin 7-O-(3''-galloyl-4'',6''-(S)-hexahydroxydiphenoyl)-β-D-glucose CFN90881 205370-59-8 20mg QQ客服:2056216494
    Pinocembrin 7-O-(3''-galloyl-4'',6''-(S)-hexahydroxydiphenoyl)-β-D-glucose CFN90881 205370-59-8 50mg QQ客服:2056216494
    Pinocembrin 7-O-(3''-galloyl-4'',6''-(S)-hexahydroxydiphenoyl)-β-D-glucose CFN90881 205370-59-8 100mg QQ客服:2056216494
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • Lund University (Sweden)
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  • Tohoku University (Japan)
  • Yale University (USA)
  • Universidad de Antioquia (Colombia)
  • Universidade Federal de Pernambuco (UFPE) (Brazil)
  • University of Fribourg (Switzerland)
  • Centrum Menselijke Erfelijkheid (Belgium)
  • Celltrion Chemical Research Institute (Korea)
  • University of Toronto (Canada)
  • University of Parma (Italy)
  • Periyar University (India)
  • Michigan State University (USA)
  • Rio de Janeiro State University (Brazil)
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  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Int J Biol Macromol.2020, 169:342-351
  • Emirates Journal of Food and Agriculture.2022, 34(6): 528-536.
  • Front Plant Sci.2021, 12:673337.
  • Plant Sci.2020, 301:110656.
  • J-STAGE2015, 249-255
  • Pak J Pharm Sci.2019, 32(6)
  • Institute of Food Science & Technology2021, 18 December.
  • Food Chem.2019, 275:746-753
  • BMC Complement Altern Med.2016, 16:213
  • Foods.2022, 11(12):1773.
  • J Food Biochem.2021, 45(7):e13774.
  • ACS Synth Biol.2022, doi: 10.1021.
  • Phytomedicine.2020, 79, 153351
  • Mol Cells.2015, 38(9):765-72
  • Food Research2021, 5(1):65-71
  • J Agric Food Chem.2021, 69(11):3496-3510.
  • Phys Chem Chem Phys.2018, 20(23):15986-15994
  • J Agric Food Chem.2016, 64(35):6783-90
  • J Drug Delivery Science and Tech.2022, 67:102957.
  • Anal Bioanal Chem.2020, 412(12):3005-3015.
  • Vietnam J. Chemistry2022, 60(2):211-222
  • Korean J. Food Sci. & Technol.2022, 54(2):241-246
  • ScientificWorldJournal.2022, 2022:4806889.
  • ...
  • 生物活性
    Description: Pinocembrin 7-O-(3''-galloyl-4'',6''-(S)-hexahydroxydiphenoyl)-beta-D-glucose can moderately inhibit α-amylase activity, with the IC50 value of 0.03 umol/ml.
    In vivo:
    J Ethnopharmacol. 2015 Apr 2;163:256-63.
    Evaluation of hypoglycemic effects of polyphenols and extracts from Penthorum chinense.[Pubmed: 25620384 ]

    METHODS AND RESULTS:
    The Penthorum chinense extract possessed anti-hyperglycemic activities as shown by the decreased serum levels of glycosylated hemoglobulin A1C (HbA1c), triglyceride(TG), total cholesterol (TC), and low density lipoprotein-cholesterol (LDL-C), as well as increased serum levels of high density lipoprotein-cholesterol (HDL-C) and insulin. Penthorum chinense extract also improved the oral glucose tolerance test (OGTT) to a certain degree. Moreover, the OSTT study showed that in diabetic rats, the extract (600mg/kg) caused a significant hypoglycemic effect with a blood glucose reduction of 42% at 60min. To identify the active constituents, three polyphenols, pinocembrin-7-O-[4″,6″-hexahydroxydiphenoyl]-β-d-glucose (1), pinocembrin-7-O-[3″-O-galloyl-4″, 6″-hexahydroxydiphenoyl]-β- d-glucose (Pinocembrin 7-O-(3''-galloyl-4'',6''-(S)-hexahydroxydiphenoyl)-beta-D-glucose,2), and thonningianin A (3) were isolated from Penthorum chinense.
    CONCLUSIONS:
    Compounds 1-3 moderately inhibited α-amylase activity, with IC50 values of 0.14, 0.03, and 0.08μmol/ml, respectively.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 1.1459 mL 5.7293 mL 11.4587 mL 22.9174 mL 28.6467 mL
    5 mM 0.2292 mL 1.1459 mL 2.2917 mL 4.5835 mL 5.7293 mL
    10 mM 0.1146 mL 0.5729 mL 1.1459 mL 2.2917 mL 2.8647 mL
    50 mM 0.0229 mL 0.1146 mL 0.2292 mL 0.4583 mL 0.5729 mL
    100 mM 0.0115 mL 0.0573 mL 0.1146 mL 0.2292 mL 0.2865 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    柯里拉京; Corilagin CFN90176 23094-69-1 C27H22O18 = 634.45 20mg QQ客服:3257982914
    诃子宁; Chebulanin CFN92294 166833-80-3 C27H24O19 = 652.5 5mg QQ客服:1413575084
    乔松苷;乔松素-7-O-β-D-葡萄糖苷; Pinocembroside CFN95444 75829-43-5 C21H22O9 = 418.4 20mg QQ客服:2159513211
    赶黄草苷B; Thonningianin B CFN91481 271579-12-5 C35H30O17 = 722.6 5mg QQ客服:3257982914
    Thonningianin A; Thonningianin A CFN90633 271579-11-4 C42H34O21 = 874.7 20mg QQ客服:1457312923
    Pinocembrin 7-O-(4'',6''-hexahydroxydiphenoyl)-beta-D-glucose; Pinocembrin 7-O-(4'',6''-hexahydroxydiphenoyl)-beta-D-glucose CFN95462 1825287-22-6 C35H28O17 = 720.6 10mg QQ客服:3257982914
    Pinocembrin 7-O-(3''-galloyl-4'',6''-(S)-hexahydroxydiphenoyl)-β-D-glucose; Pinocembrin 7-O-(3''-galloyl-4'',6''-(S)-hexahydroxydiphenoyl)-beta-D-glucose CFN90881 205370-59-8 C42H32O21 = 872.7 20mg QQ客服:2159513211
    2,6-Dihydroxyacetophenone-4-O-[4',6'-(S)-hexahydroxydiphenoyl]-beta-D-glucose; 2,6-Dihydroxyacetophenone-4-O-[4',6'-(S)-hexahydroxydiphenoyl]-beta-D-glucose CFN95470 1781226-44-5 C28H24O17 = 632.5 5mg QQ客服:2159513211
    老鹳草素; Geraniin CFN90256 60976-49-0 C41H28O27 = 952.64 20mg QQ客服:215959384
    叶下珠鞣质C; Phyllanthusiin C CFN95260 142674-52-0 C40H30O26 = 926.7 5mg QQ客服:2159513211

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