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  • 苦鬼臼毒素

    Picropodophyllotoxin

    苦鬼臼毒素
    产品编号 CFN90443
    CAS编号 17434-18-3
    分子式 = 分子量 C22H22O8 = 414.4
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Lignans
    植物来源 The rhizomes of Dysosma versipellis (Hance.) M.Cheng
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    苦鬼臼毒素 CFN90443 17434-18-3 10mg QQ客服:2159513211
    苦鬼臼毒素 CFN90443 17434-18-3 20mg QQ客服:2159513211
    苦鬼臼毒素 CFN90443 17434-18-3 50mg QQ客服:2159513211
    苦鬼臼毒素 CFN90443 17434-18-3 100mg QQ客服:2159513211
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
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  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Asian J Beauty Cosmetol2021, 19(1): 57-64.
  • Braz J Biol.2023, 82:e266573.
  • Naunyn Schmiedebergs Arch Pharmacol.2017, 390(10):1073-1083
  • British Jou. Med.&Med. Research2014, 1802-1811
  • Oxid Med Cell Longev2020, 12
  • Oncol Rep.2021, 46(1):143.
  • J Chromatogr B Analyt Technol Biomed Life Sci.2020, 1149:122123.
  • Front Pharmacol.2021, 12:744624.
  • Research J. Pharm. and Tech.2020, 13(7):3059-3064.
  • Pharmaceuticals (Basel).2021, 14(3):260.
  • J Separation Science & Technology2016, 51:1579-1588
  • Pharmacol Rep.2020, 72(2):472-480.
  • Chemistry of Natural Compounds2020, 56,423-426
  • Int J Mol Sci.2018, 19(9):E2681
  • Pol J Microbiol.2021, 70(1):117-130.
  • Plants (Basel).2021, 10(2):278.
  • Biomolecules.2019, 9(11):E696
  • Front Pharmacol.2023, 14:1244655.
  • Int J Mol Sci.2023, 24(18):14077.
  • Food Research International2016, 106-113
  • Microb Pathog.2019, 131:128-134
  • Medicinal Chemistry Research 2021, 30:1117-1124.
  • Eur Endod J.2020, 5(1):23-27.
  • ...
  • 生物活性
    Description: Picropodophyllotoxin shows highly antifeeding and toxic activities against the 3rd-instar larve of Mythimna separate W.and the 4th-instar larvae of Pieris rapae L.and the 3rd-instar larve of Plutella xylostella L.
    In vitro:
    《Journal of Northwest A & F University(Natural Science Edition)》 2007-09
    Study on 6 insecticidal podophyllotoxin compounds from the berries of Sabina vulgaris Ant.[Reference: WebLink]
    In order to isolate other insecticidal podophyllotoxin compounds from the berries of Sabina vulgaris Ant.,six podophyllotoxin compounds were isolated by tracing with insecticidal activity.They were identified as acetyl Picropodophyllotoxin,deoxyPicropodophyllotoxin,acetyl epipodophyllotoxin,podophyllotoxin,deoxypodophyllotoxin and Picropodophyllotoxin.
    METHODS AND RESULTS:
    The antifeeding activities against the 3rd-instar larve of Mythimna separate W.and the toxic activities against the 4th-instar larvae of Pieris rapae L.and the 3rd-instar larve of Plutella xylostella L.were tested by leaf-disk method and leaf-dipping method,respectively.The bioassay results indicated that all these compounds showed highly antifeeding and toxic activities against the 3 tested insects.Podophyllotoxin and deoxypodophyllotoxin were the two with the highest insecticidal activities among the six,while Picropodophyllotoxin was the lowest.Besides,acetyl Picropodophyllotoxin,deoxyPicropodophyllotoxin,acetyl epipodophyllotoxin and Picropodophyllotoxin were insecticidal compounds firstly reported from S.vulgaris.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 2.4131 mL 12.0656 mL 24.1313 mL 48.2625 mL 60.3282 mL
    5 mM 0.4826 mL 2.4131 mL 4.8263 mL 9.6525 mL 12.0656 mL
    10 mM 0.2413 mL 1.2066 mL 2.4131 mL 4.8263 mL 6.0328 mL
    50 mM 0.0483 mL 0.2413 mL 0.4826 mL 0.9653 mL 1.2066 mL
    100 mM 0.0241 mL 0.1207 mL 0.2413 mL 0.4826 mL 0.6033 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    alpha-盾叶鬼臼素; alpha-Peltatin CFN70412 568-53-6 C21H20O8 = 400.4 5mg QQ客服:2159513211
    (-)-β-盾叶鬼臼素; (-)-beta-Peltatin CFN92699 518-29-6 C22H22O8 = 414.4 5mg QQ客服:2056216494
    (-)-β-盾叶鬼臼素-5-O-β-葡萄糖甙; (-)-beta-Peltatin-5-O-beta-D-glucopyranoside CFN92700 11024-59-2 C28H32O13 = 576.6 5mg QQ客服:2159513211
    去氧鬼臼脂素; Deoxypodophyllotoxin CFN99888 19186-35-7 C22H22O7 = 398.4 10mg QQ客服:1413575084
    4'-去甲鬼臼毒素; 4'-Demethylpodophyllotoxin CFN90483 40505-27-9 C21H20O8 = 400.37 20mg QQ客服:2056216494
    依托泊甙; Etoposide CFN89061 33419-42-0 C29H32O13 = 588.56 20mg QQ客服:1457312923
    Podophyllotoxinone; Podophyllotoxinone CFN91909 477-49-6 C22H20O8 = 412.39 5mg QQ客服:215959384
    苦鬼臼毒素; Picropodophyllotoxin CFN90443 17434-18-3 C22H22O8 = 414.4 20mg QQ客服:1457312923
    鬼臼毒素; Podophyllotoxin CFN99168 518-28-5 C22H22O8 = 414.41 20mg QQ客服:215959384
    表鬼臼毒素; Epipodophyllotoxin CFN91618 4375-07-9 C22H22O8 = 414.41 5mg QQ客服:3257982914

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