Info: Read More
  • 中药标准品生产商,产品定制服务
  • 菜豆蛋白

    Phaseollin

    菜豆蛋白
    产品编号 CFN97946
    CAS编号 13401-40-6
    分子式 = 分子量 C20H18O4 = 322.4
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Flavonoids
    植物来源 The herbs of Erythrina addisoniae
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    菜豆蛋白 CFN97946 13401-40-6 1mg QQ客服:1457312923
    菜豆蛋白 CFN97946 13401-40-6 5mg QQ客服:1457312923
    菜豆蛋白 CFN97946 13401-40-6 10mg QQ客服:1457312923
    菜豆蛋白 CFN97946 13401-40-6 20mg QQ客服:1457312923
    存储与注意事项
    1. 在您收到产品后请检查产品。如无问题,请将产品存入冰霜并且样品瓶保持密封,产品可以存放长达24个月(2-8摄氏度)。

    2. 只要有可能,产品溶解后,您应该在同一天应用于您的实验。 但是,如果您需要提前做预实验,或者需要全部溶解,我们建议您将溶液以等分试样的形式存放在-20℃的密封小瓶中。 通常,这些可用于长达两周。 使用前,打开样品瓶前,我们建议您将产品平衡至室温至少1小时。

    3. 需要更多关于溶解度,使用和处理的建议? 请发送电子邮件至:service@chemfaces.com
    订购流程
  • 1. 在线订购
  • 请联系我们QQ客服

  • 2. 电话订购
  • 请拨打电话:
    027-84237683 或 027-84237783

  • 3. 邮件或传真订购
  • 发送电子邮件到: manager@chemfaces.com 或
    发送传真到:027-84254680

  • 提供订购信息
  • 为了方便客户的订购,请需要订购ChemFaces产品的客户,在下单的时候请提供下列信息,以供我们快速为您建立发货信息。
  •  
  • 1. 产品编号(CAS No.或产品名称)
  • 2. 发货地址
  • 3. 联系方法 (联系人,电话)
  • 4. 开票抬头 (如果需要发票的客户)
  • 5. 发票地址(发货地址与发票地址不同)
  • 发货时间
    1. 付款方式为100%预付款客户,我们将在确认收到货款后当天或1-3个工作日发货。

    2. 付款方式为月结的客户,我们承诺在收到订单后当天或1-3个工作日内发货。

    3. 如果客户所需要的产品,需要重新生产,我们有权告知客户,交货时间需要延期。
    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • Colorado State University (USA)
  • Institute of Bioorganic Chemistry Polish Academy of Sciences (Poland)
  • Molecular Biology Institute of Barcelona (IBMB)-CSIC (Spain)
  • Leibniz-Institut für Pflanzenbiochemie (IPB) (Germany)
  • Periyar University (India)
  • Worcester Polytechnic Institute (USA)
  • Ateneo de Manila University (Philippines)
  • University of the Basque Country (Spain)
  • Universite Libre de Bruxelles (Belgium)
  • Cancer Research Initatives Foundation(CARIF) (Malaysia)
  • Kyushu University (Japan)
  • Universidade Federal de Goias (UFG) (Brazil)
  • Charles University in Prague (Czech Republic)
  • Washington State University (USA)
  • More...
  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • HIV Med.2021, 22(8):690-704.
  • J of the Society of Cosmetic Scientists of Korea2018, 44(4):407-417
  • J of Applied Pharmaceutical Science2020, 10(1):077-082
  • Molecules.2021, 26(3):695.
  • Sci Rep.2017, 7:467-479
  • Sci Rep. 2017, 17332(7)
  • Phytother Res.2022, 10.1002:ptr.7592.
  • Nutrients2023, 15(18), 4016.
  • J Ethnopharmacol.2020, 249:112396
  • Korean J of Food Science&Technology 2017, 49(2):146-150
  • Fitoterapia.2018, 124:92-102
  • Int J Mol Med.2016, 37(2):501-8
  • J Am Soc Mass Spectrom.2021, 32(5):1205-1214.
  • Pharmacognosy Journal.2020, 12(2), p232-235.
  • Food Sci Biotechnol.2016, 25(5):1437-1442
  • J Ethnopharmacol.2017, 198:91-97
  • Toxicol Mech Methods.2021, 1-12.
  • UDC.2020, 19(4).
  • Biosci Biotechnol Biochem.2021, 85(10):2153-2160.
  • J Pharmaceutical and Biomedical Analysis2022, 114631.
  • Anal Chim Acta.2021, 1180:338874.
  • Food and Fermentation Industries2019, 45(7):45-51
  • Pharmaceutics.2021, 13(2):187.
  • ...
  • 生物活性
    Description: Phaseollin and neorautenol may be responsible for the anticarcinogenic actions of the plant extract, may lead to new pharmacons to be used in cancer therapy.9-Aminoacridine and other DNA intercalators function as inducers of Phaseollin and phenylalanine ammonia lyase synthesis by reacting with the DNA template.The red kidney bean phytoalexins kievitone and phaseollin possess both estrogenic and antiestrogenic activities.
    Targets: ERK | p65 | NF-kB | TNF-α | Estrogen receptor | Progestogen receptor
    In vitro:
    J Agric Food Chem. 2011 Jan 12;59(1):112-20.
    Estrogenic and antiestrogenic activities of phytoalexins from red kidney bean (Phaseolus vulgaris L.).[Pubmed: 21133423 ]

    METHODS AND RESULTS:
    The phytoalexins kievitone and Phaseollin were isolated from A. sojae-treated red kidney bean extracts and analyzed for estrogenic activity using ERα and ERβ binding, ERE luciferase assays in MCF-7 and HEK 293 cells, and MCF-7 cell proliferation. Kievitone showed the highest relative binding affinity to ERα with kievitone (0.48%) > Phaseollin (0.21%), and Phaseollin showed the highest relative binding affinity to ERβ with Phaseollin (0.53%) > kievitone (0.42%). In an ERE luciferase assay in MCF-7 cells, kievitone displayed high ER transactivation at 10 μM; Phaseollin displayed low ER transactivation. Both kievitone and Phaseollin stimulated MCF-7 cell proliferation, with kievitone displaying agonist activity between 0.1 and 10 μM. Cotransfection reporter assays performed in HEK 293 demonstrated that Phaseollin selectively increased ERE transcriptional activity of ERβ and kievitone selectively increased ERE transcriptional activity of ERα. Although Phaseollin displayed attenuation of ER transactivation in the ERE luciferase assay in MCF-7 cells, both phytoalexins attenuated the effects of E2 in an MCF-7 cell colonial survival assay.
    CONCLUSIONS:
    This work provides evidence that the red kidney bean phytoalexins kievitone and Phaseollin possess both estrogenic and antiestrogenic activities.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 3.1017 mL 15.5087 mL 31.0174 mL 62.0347 mL 77.5434 mL
    5 mM 0.6203 mL 3.1017 mL 6.2035 mL 12.4069 mL 15.5087 mL
    10 mM 0.3102 mL 1.5509 mL 3.1017 mL 6.2035 mL 7.7543 mL
    50 mM 0.062 mL 0.3102 mL 0.6203 mL 1.2407 mL 1.5509 mL
    100 mM 0.031 mL 0.1551 mL 0.3102 mL 0.6203 mL 0.7754 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    Barbacarpan; Barbacarpan CFN98069 213912-46-0 C20H18O4 = 322.4 5mg QQ客服:1413575084
    菜豆蛋白; Phaseollin CFN97946 13401-40-6 C20H18O4 = 322.4 5mg QQ客服:3257982914
    6a,11a-去氢块葛黄酮; Anhydrotuberosin CFN98647 41347-49-3 C20H16O4 = 320.3 5mg QQ客服:1457312923
    1-甲氧基菜豆素; 1-Methoxyphaseollidin CFN96878 65428-13-9 C21H22O5 = 354.40 5mg QQ客服:215959384
    块葛黄酮; Tuberosin CFN95107 41347-45-9 C20H18O5 = 338.4 5mg QQ客服:215959384
    羟基晚香玉酮; Hydroxytuberosone CFN97592 95456-43-2 C20H18O6 = 354.36 5mg QQ客服:1457312923
    Glyurallin A; Glyurallin A CFN89255 199331-36-7 C21H20O5 = 352.38 5mg QQ客服:3257982914
    阿比西尼亚桐素II; Erythrabyssin II CFN97959 77263-06-0 C25H28O4 = 392.5 5mg QQ客服:1413575084
    Phaseollidin hydrate; Phaseollidin hydrate CFN96054 76122-57-1 C20H22O5 = 342.4 5mg QQ客服:1413575084
    刺桐酚素; Cristacarpin CFN96024 74515-47-2 C21H22O5 = 354.4 5mg QQ客服:3257982914

    信息支持


    公司简介
    订购流程
    付款方式
    退换货政策

    ChemFaces提供的产品仅用于科学研究使用,不用于诊断或治疗程序。

    联系方式


    电机:027-84237783
    传真:027-84254680
    在线QQ: 1413575084
    E-Mail:manager@chemfaces.com

    湖北省武汉沌口经济技术开区车城南路83号1号楼第三层厂房


    ChemFaces为科学家,科研人员与企业提供快速的产品递送。我们通过瑞士SGS ISO 9001:2008质量体系认证天然化合物与对照品的研发和生产