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  • 芍药内苷B

    Paeonilactone B

    芍药内苷B
    产品编号 CFN96055
    CAS编号 98751-78-1
    分子式 = 分子量 C10H12O4 = 196.2
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Monoterpenoids
    植物来源 The roots of Paeonia albiflora
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    芍药内苷B CFN96055 98751-78-1 1mg QQ客服:2159513211
    芍药内苷B CFN96055 98751-78-1 5mg QQ客服:2159513211
    芍药内苷B CFN96055 98751-78-1 10mg QQ客服:2159513211
    芍药内苷B CFN96055 98751-78-1 20mg QQ客服:2159513211
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
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  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Industrial Crops and Products2022, 188:115638
  • Int J Mol Sci.2020, 21(22):8816.
  • Food Chem.2022, 378:131975.
  • J Nat Med.2017, 71(4):745-756
  • Nat Plants.2016, 3:16205
  • Primary and Industrial.2018, 52(11)
  • J Formos Med Assoc.2020, S0929-6646(20)30425-3
  • Int J Cosmet Sci.2023, 45(2):155-165.
  • Evid Based Complement Alternat Med.2017, 2017:6360836
  • Trop J Nat Prod Res.2019, 3(1):6-9
  • Phytochem Anal.2013, 24(5):493-503
  • Int J Oncol.2019, 55(1):320-330
  • Asian J Beauty Cosmetol2021, 19(1): 57-64.
  • Biomol Ther (Seoul).2023, 31(1):40-47.
  • Nutrients.2023, 15(4):954.
  • Mol Pharm.2017, 14(9):3164-3177
  • Front Plant Sci.2021, 12: 648426.
  • Nat Chem Biol.2018, 14(8):760-763
  • Metab Eng.2022, 75:143-152.
  • J Vet Sci.2020, 21(3):e39.
  • Biomedicines.2021, 9(8):954.
  • Front Cell Dev Biol.2020, 8:32.
  • Eur J Pharmacol.2018, 832:96-103
  • ...
  • 生物活性
    Description: Paeonilactone B is a natural product from Paeonia albiflora.
    Targets: NADPH-oxidase
    In vitro:
    Chem Pharm Bull (Tokyo). 1993 Mar;41(3):487-90.
    Palbinone, a novel terpenoid from Paeonia albiflora; potent inhibitory activity on 3 alpha-hydroxysteroid dehydrogenase.[Pubmed: 8477499]

    METHODS AND RESULTS:
    Palbinone, a novel terpenoid isolated from the roots of Paeonia albiflora, showed a strong inhibitory activity on the reduced form of nicotinamide adenine dinucleotide phosphate (NADPH)-linked 3 alpha-hydroxysteroid dehydrogenase (3 alpha-HSD) of rat liver cytosol. The structures of palbinone and a known compound,
    CONCLUSIONS:
    Paeonilactone B isolated from the active fraction of this plant were determined by the use of 2D NMR techniques (1H-1H COSY, 1H-13C COSY, 1H-13C long-range COSY, and HMBC).
    J Enzyme Inhib Med Chem. 2009 Oct;24(5):1138-40.
    Chemical constituents isolated from Paeonia lactiflora roots and their neuroprotective activity against oxidative stress in vitro.[Pubmed: 19772486 ]

    METHODS AND RESULTS:
    The methanolic extract of Paeonia lactiflora roots significantly protected primary cultures of rat cortical cells exposed to oxidative stress induced by H(2)O(2). Seven monoterpenes, Paeonilactone B (1), paeonilactone C (2), paeoniflorigenone (3), benzoylpaeoniflorin (4), paeoniflorin (5), oxypaeoniflorin (6) and albiflorin (7), were isolated by bioactivity-guided fractionation and further separation using chromatographic techniques.
    CONCLUSIONS:
    Among them, compounds 2 and 4 significantly protected primary cultures of rat cortical cells against H(2)O(2)-induced neurotoxicity.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 5.0968 mL 25.4842 mL 50.9684 mL 101.9368 mL 127.421 mL
    5 mM 1.0194 mL 5.0968 mL 10.1937 mL 20.3874 mL 25.4842 mL
    10 mM 0.5097 mL 2.5484 mL 5.0968 mL 10.1937 mL 12.7421 mL
    50 mM 0.1019 mL 0.5097 mL 1.0194 mL 2.0387 mL 2.5484 mL
    100 mM 0.051 mL 0.2548 mL 0.5097 mL 1.0194 mL 1.2742 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    芍药内苷C; Paeonilactone C CFN96056 98751-77-0 C17H18O6 = 318.3 5mg QQ客服:1457312923
    芍药内苷A; Paeonilactone A CFN96059 98751-79-2 C10H14O4 = 198.2 5mg QQ客服:2159513211
    苯甲酰芍药内酯苷; Benzoylalbiflorin CFN91579 184103-78-4 C30H32O12 = 584.6 10mg QQ客服:1457312923
    芍药苷; Paeoniflorin CFN99544 23180-57-6 C23H28O11 = 480.45 20mg QQ客服:1413575084
    氧化芍药苷; Oxypaeoniflorin CFN99589 39011-91-1 C23H28O12 = 496.46 20mg QQ客服:215959384
    2'-O-苯甲酰基芍药甙; 2'-O-Benzoylpaeoniflorin CFN89529 1456598-64-3 C30H32O12 = 584.56 5mg QQ客服:2159513211
    苯甲酰芍药苷; Benzoylpaeoniflorin CFN99536 38642-49-8 C30H32O12 = 584.57 20mg QQ客服:1413575084
    苯甲酰氧化芍药苷; Benzoyloxypeoniflorin CFN90662 72896-40-3 C30H32O13 = 600.57 20mg QQ客服:215959384
    牡丹皮苷C; Mudanpioside C CFN90661 172760-03-1 C30H32O13 = 600.57 20mg QQ客服:2159513211
    没食子酰芍药苷; Galloylpaeoniflorin CFN90831 122965-41-7 C30H32O15 = 632.6 10mg QQ客服:3257982914

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