| In vitro: |
| Zhongguo Zhong Yao Za Zhi. 2013 Aug;38(16):2657-60. | | Chemical constituents of Paederia pertomentosa.[Pubmed: 24228582] | Five constituents were extracted from the aerial part of Paederia pertomentosa and isolated by column chromatography.
METHODS AND RESULTS:
Their structures were elucidated by physicochemical properties and spectroscopic data analysis. The isolated compounds were identified as 1,2-dimethoxy-3,4-dihydroxyanthraquinone named as paederone (1), Paederoside (2), deacetyl asperulosidic acid methyl ester (3), paederosidic acid (4) and methylpaederosidate (5). Compound 1 is a new compound which exhibits a significant inhibitory effect on Escherichia coli and Staphylococcus aureus. Compounds 2-5 were isolated from this plant for the first time. | | Cancer Lett., 1996, 102(1-2):223-6. | | Inhibitory effect of iridoids on Epstein-Barr virus activation by a short-term in vitro assay for anti-tumor promoters.[Pubmed: 8603374] | The in vitro anti-tumor promoting effect of the methanolic extracts of iridoids containing three plants and several pure iridoids isolated from other plants, has been evaluated.
METHODS AND RESULTS:
The alcoholic extracts of Paederia scandens, P. scandens var. mairei and the Ayurvedic herbal remedy Picrorhiza kurrooa were tested against the Epstein-Barr virus.
Among the 15 iridoids evaluated, the glycoside, Paederoside, displayed the highest order of anti-tumor promoting activity. |
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