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  • Niazinin

    Niazinin

    Niazinin
    产品编号 CFN89344
    CAS编号 147821-57-6
    分子式 = 分子量 C15H21NO6S = 343.39
    产品纯度 >=98%
    物理属性 Oil
    化合物类型 Phenols
    植物来源 The leaves of Moringa oleifera Lam.
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    Niazinin CFN89344 147821-57-6 1mg QQ客服:1413575084
    Niazinin CFN89344 147821-57-6 5mg QQ客服:1413575084
    Niazinin CFN89344 147821-57-6 10mg QQ客服:1413575084
    Niazinin CFN89344 147821-57-6 20mg QQ客服:1413575084
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • University of Malaya (Malaysia)
  • University of Vigo (Spain)
  • University of East Anglia (United Kingdom)
  • Instytut Nawozów Sztucznych w Pu?awach (Poland)
  • Medical University of Gdansk (Poland)
  • University of Hawaii Cancer Center (USA)
  • Washington State University (USA)
  • Sri Ramachandra University (India)
  • Kyung Hee University (Korea)
  • University of Minnesota (USA)
  • Aveiro University (Portugal)
  • Medizinische Universit?t Wien (Austria)
  • Griffith University (Australia)
  • Universidade de Franca (Brazil)
  • More...
  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Planta Med.2023, a-2192-2281.
  • Plants (Basel).2021, 10(11):2525.
  • Molecules.2022, 27(7):2360.
  • J. Food Composition and Analysis2022, 114:104731
  • J Adv Res.2021, 35:245-257.
  • Int J Mol Sci.2022, 23(21):13406.
  • J Sci Food Agric.2018, 98(3):1153-1161
  • Int J Mol Sci.2021, 22(11):5503.
  • Food Science and Biotechnology2015, 2205-2212
  • J Korean Society of Food Science & Nutrition2021, 50(9): 962-970
  • Evid Based Complement Alternat Med.2018, 2018:4259603
  • Antioxidants (Basel).2021, 10(1):112.
  • Front. Plant Sci.2022, 13:757852.
  • Evid Based Complement Alternat Med.2022, 2022:3483511
  • Molecules.2019, 24(10):E1930
  • J Ethnopharmacol.2017, 197:157-164
  • Oncology Letters2018, 4690-4696
  • Int J Mol Sci.2019, 20(3):E651
  • BMC Complement Altern Med.2018, 18(1):303
  • Horticulturae2023, 9(2), 213.
  • Food Funct.2021, 12(13):5892-5902.
  • Biol Pharm Bull.2020, 43(10):1534-1541.
  • Int J Mol Sci.2018, 19(9):E2601
  • ...
  • 生物活性
    Description: Niazinin shows antileishmanial activity against promastigotes of Leishmania donavani, with an IC50 value of 5.25 microM.
    Targets: Antifection
    In vitro:
    Z Naturforsch C. 2014 Mar-Apr;69(3-4):110-6.
    Antileishmanial compounds from Moringa oleifera Lam.[Pubmed: 24873031]
    The antileishmanial activity of extracts and phytoconstituents of Moringa oleifera Lam. was investigated in vitro against promastigotes of Leishmania donavani.
    METHODS AND RESULTS:
    The 70% ethanolic extract of roots and the methanolic extract of leaves showed moderate inhibitory activity with IC50 values of 83.0 microg/ml and 47.5 microg/ml, respectively. Antileishmanial activity of the methanolic extract of leaves increased upon fractionation, as its ethyl acetate fraction was found to be more active with an IC50 value of 27.5 microg/ml. The most active antileishmanial compound Niazinin, a thiocarbamate glycoside isolated from this fraction, showed an IC50 value of 5.25 microM.
    CONCLUSIONS:
    Results presented in this study indicate that extracts from M. oleifera may be developed as an adjuvant therapy for the treatment of leishmaniasis.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 2.9121 mL 14.5607 mL 29.1214 mL 58.2428 mL 72.8035 mL
    5 mM 0.5824 mL 2.9121 mL 5.8243 mL 11.6486 mL 14.5607 mL
    10 mM 0.2912 mL 1.4561 mL 2.9121 mL 5.8243 mL 7.2804 mL
    50 mM 0.0582 mL 0.2912 mL 0.5824 mL 1.1649 mL 1.4561 mL
    100 mM 0.0291 mL 0.1456 mL 0.2912 mL 0.5824 mL 0.728 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    钝叶扁柏氨基甲酸酯 A; Obtucarbamate A CFN96025 6935-99-5 C11H14N2O4 = 238.2 20mg QQ客服:1457312923
    钝叶扁柏氨基甲酸酯 B; Obtucarbamate B CFN96026 20913-18-2 C11H14N2O4 = 238.2 10mg QQ客服:2159513211
    2-氨基-1-苯乙醇; 2-Amino-1-phenylethanol CFN00052 111025-00-4 C15H15NO2 = 241.29 5mg QQ客服:2056216494
    N-Benzoyl-2-hydroxy-2-phenylethylamine; N-Benzoyl-2-hydroxy-2-phenylethylamine CFN00053 111059-46-2 C15H15NO2 = 241.29 5mg QQ客服:1413575084
    Muricatide; Muricatide CFN00054 111025-01-5 C17H17NO3 = 283.33 5mg QQ客服:215959384
    苄胺; Benzylamine CFN00064 100-46-9 C7H9N = 107.15 5mg QQ客服:1413575084
    N-甲基苄胺; N-Methylbenzylamine CFN00065 103-67-3 C8H11N = 121.18 5mg QQ客服:3257982914
    2-羟基苄胺; 2-Hydroxybenzylamine CFN00079 932-30-9 C7H9NO = 123.15 20mg QQ客服:215959384
    3-氨甲基苯酚; 3-Hydroxybenzylamine CFN00080 73604-31-6 C7H9NO = 123.15 5mg QQ客服:2159513211
    4-羟基苄胺; 4-Hydroxybenzylamine CFN00081 696-60-6 C7H9NO = 123.15 5mg QQ客服:2056216494

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