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  • 罗汉果皂苷III-A2

    Mogroside III-A2

    罗汉果皂苷III-A2
    产品编号 CFN92946
    CAS编号 88901-43-3
    分子式 = 分子量 C48H82O19 = 963.15
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Triterpenoids
    植物来源 The fruits of Siraitia grosvenorii Swingle.
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    罗汉果皂苷III-A2 CFN92946 88901-43-3 1mg QQ客服:1413575084
    罗汉果皂苷III-A2 CFN92946 88901-43-3 5mg QQ客服:1413575084
    罗汉果皂苷III-A2 CFN92946 88901-43-3 10mg QQ客服:1413575084
    罗汉果皂苷III-A2 CFN92946 88901-43-3 20mg QQ客服:1413575084
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
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  • Florida International University (USA)
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  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • ACS Nano.2018, 12(4):3385-3396
  • Phytomedicine.2015, 22(4):498-503
  • Int J Mol Sci.2021, 22(16):8604.
  • Korean Journal of Pharmacognosy2017, 48(4):320-328
  • J Sci Food Agric.2018, 98(3):1153-1161
  • Front Pharmacol.2021, 12:607403.
  • Sci Rep.2019, 9(1):4342
  • Research J. Pharm. and Tech.2020, 13(7):3059-3064.
  • J Pharm Biomed Anal.2019, 164:119-127
  • Molecules.2023, 28(3):958.
  • Int J Mol Sci. 2014, 15(5):8443-57
  • Evid Based Complement Alternat Med.2017, 2017:1583185
  • Pharmacognosy Journal.2020, 12(2), p232-235.
  • Cell Mol Biol(Noisy-le-grand)2019, 65(7):77-83
  • Mol Pharmacol.2021, 99(2):163-174.
  • Life (Basel).2022, 12(10):1630.
  • Nutrients2022, 14(14)2929
  • J Nat Med.2017, 71(2):380-388
  • Pharmacol Res.2022, 182:106346.
  • PLoS One.2022, 17(6):e0268505.
  • J Ethnopharmacol.2022, 291:115159.
  • Fitoterapia.2015, 100:179-86
  • Sci Rep.2018, 8:15059
  • ...
  • 生物活性
    Description: Mogroside III-A2 exhibits inhibitory effects with IC50 values of 346-400 mol ratio/32 pmol TPA. and shows weak inhibitory effects on activation of (+/-)-(E)-methyl-2-[(E)-hydroxyimino]-5-nitro-6-methoxy-3-hexemide (NOR 1), a nitric oxide (NO) donor.
    Targets: NO
    In vitro:
    J Nat Prod. 2007 May;70(5):783-8.
    Cucurbitane glycosides from the fruits of Siraitia gros venorii and their inhibitory effects on Epstein-Barr virus activation.[Pubmed: 17477572 ]

    METHODS AND RESULTS:
    Six new cucurbitane glycosides, mogroside II B (2), 11-deoxymogroside III (4), 7-oxomogroside II E (5), 7-oxomogroside V (6), 11-oxomogroside II A1 (7), and 11-oxomogroside IV A (8), and two known but new naturally occurring cucurbitane glycosides, mogroside II-A1 (1) and Mogroside III-A2 (3), were isolated from an ethanol extract of the fruits of Siraitia grosvenorii.
    CONCLUSIONS:
    Upon evaluation of compounds 1-8 for inhibitory effects against the Epstein-Barr virus early antigen (EBV-EA) activation induced by 12-O-tetradecanoylphorbol-13-acetate (TPA), all compounds exhibited inhibitory effects with IC50 values of 346-400 mol ratio/32 pmol TPA. In addition, compounds 1-8 showed weak inhibitory effects on activation of (+/-)-(E)-methyl-2-[(E)-hydroxyimino]-5-nitro-6-methoxy-3-hexemide (NOR 1), a nitric oxide (NO) donor.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 1.0383 mL 5.1913 mL 10.3826 mL 20.7652 mL 25.9565 mL
    5 mM 0.2077 mL 1.0383 mL 2.0765 mL 4.153 mL 5.1913 mL
    10 mM 0.1038 mL 0.5191 mL 1.0383 mL 2.0765 mL 2.5956 mL
    50 mM 0.0208 mL 0.1038 mL 0.2077 mL 0.4153 mL 0.5191 mL
    100 mM 0.0104 mL 0.0519 mL 0.1038 mL 0.2077 mL 0.2596 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    11-氧-罗汉果皂苷IIA1; 11-Oxomogroside II A1 CFN95606 942612-74-0 C42H70O14 = 799.0 5mg QQ客服:1413575084
    罗汉果皂苷III-A1; Mogroside III-A1 CFN92193 88901-42-2 C48H82O19 = 963.2 10mg QQ客服:2056216494
    罗汉果皂苷III-A2; Mogroside III-A2 CFN92946 88901-43-3 C48H82O19 = 963.15 5mg QQ客服:215959384
    罗汉果皂苷IIIe; Mogroside IIIe CFN92945 88901-37-5 C48H82O19 = 963.15 10mg QQ客服:2056216494
    翅子罗汉果I; Siamenoside I CFN90398 126105-12-2 C54H92O24 = 1125.29 20mg QQ客服:3257982914
    罗汉果糖苷V; 罗汉果皂甙V; Mogroside V CFN99937 88901-36-4 C60H102O29 = 1287.44 20mg QQ客服:2159513211
    异-罗汉果皂苷V; Iso-mogroside V CFN92065 1126032-65-2 C60H102O29 = 1287.5 10mg QQ客服:1413575084
    11-O-罗汉果苷V; 11-Oxo-mogroside V CFN90365 126105-11-1 C60H100O29 = 1285.42 20mg QQ客服:3257982914
    11-去氧罗汉果苷V; 11-Deoxymogroside V CFN80166 1707161-17-8 C60H102O28 = 1271.44 10mg QQ客服:3257982914
    11-去氧异罗汉果苷V; 11-Deoxyisomogroside V CFN95288 1628293-32-2 C60H102O28 = 1271.5 10mg QQ客服:215959384

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