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  • 迷迭香酸甲酯

    Methyl rosmarinate

    迷迭香酸甲酯
    产品编号 CFN97567
    CAS编号 99353-00-1
    分子式 = 分子量 C19H18O8 = 374.4
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Phenylpropanoids
    植物来源 The herbs of Rosmarinus officinalis L.
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    迷迭香酸甲酯 CFN97567 99353-00-1 10mg QQ客服:3257982914
    迷迭香酸甲酯 CFN97567 99353-00-1 20mg QQ客服:3257982914
    迷迭香酸甲酯 CFN97567 99353-00-1 50mg QQ客服:3257982914
    迷迭香酸甲酯 CFN97567 99353-00-1 100mg QQ客服:3257982914
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • Almansora University (Egypt)
  • Universidad Industrial de Santander (Colombia)
  • Aarhus University (Denmark)
  • Universite Libre de Bruxelles (Belgium)
  • Universiti Kebangsaan Malaysia (Malaysia)
  • Celltrion Chemical Research Institute (Korea)
  • Uniwersytet Jagielloński w Krakowie (Poland)
  • University of Amsterdam (Netherlands)
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  • Georgia Institute of Technology (USA)
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  • Vin?a Institute of Nuclear Sciences (Serbia)
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  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Front Microbiol.2023, 14:1232039.
  • Biochem Biophys Res Commun.2018, 505(1):194-200
  • Biochem Pharmacol.2017, 130:10-20
  • Synthetic and Systems Biotechnology2023, j.synbio.
  • Nat Prod Commun.2014, 9(5):679-82
  • Antioxidants (Basel).2020, 9(11):1121.
  • Front Pharmacol.2022, 13:906763.
  • Environ Toxicol.2022, 37(3):514-526.
  • Sci Rep.2019, 9:12132
  • Molecules.2020, 25(15):3353.
  • Foods.2021, 10(6):1378.
  • Nat Prod Sci.2018, 24(2):109-114
  • Mol Divers.2022, s11030-022-10586-3.
  • J Ethnopharmacol.2017, 198:87-90
  • An Acad Bras Cienc.2023, 95(3):e20220672
  • Nutrients.2023, 15(6):1335.
  • Antioxidants.2022, 11(4), 67.
  • Phytochem Anal.2023, pca.3305.
  • J Agric Food Chem.2016, 64(35):6783-90
  • J Ethnopharmacol.2019, 244:112074
  • J Cell Biochem.2022, 123(7):1222-1236.
  • Sustainability2021, 13(23),12981.
  • Int J Mol Sci.2021, 22(16):8641.
  • ...
  • 生物活性
    Description: Methyl rosmarinate shows antioxidative, and antifungal activities. It has inhibitory activities against tyrosinase, α-glucosidase, and matrix metalloproteinase-1 (MMP-1).
    Targets: Tyrosinase | Antifection | MMP(e.g.TIMP)
    In vitro:
    J Food Prot. 2013 Sep;76(9):1539-48.
    Impact of fatty acid chain length of rosmarinate esters on their antimicrobial activity against Staphylococcus carnosus LTH1502 and Escherichia coli K-12 LTH4263.[Pubmed: 23992498 ]
    The effect of the addition of a newly synthesized series of rosmarinic acid (RA) estes (REs) and alcohols with chain lengths of 1, 4, 8, 10, 12, 16, and 18 carbons (RE1 to 18) on the growth behavior of Staphylococcus carnosus LTH1502 and Escherichia coli K-12 LTH4263 was investigated.
    METHODS AND RESULTS:
    An initial microtiter dilution assay indicated activity of compounds against S. carnosus LTH1502, whereas esters with chain lengths, RA, n-Methyl rosmarinate (RE1), n-dodecyl rosmarinate (RE12), and n-octadecyl rosmarinate (RE18) were used in a time-kill assay S. carnosus LTH1502. Compounds were added at 0.75 mM in the log phase, 5 mM in the exponential phase, 10 mM in the stationary phase. RA had no effect in the lag and exponential phase but decreased cell counts during the stationary phase. In contrast, RE1 and RE12 decreased cell number in all three phase, will RE12 reducing counts most rapidly. Addition of RE18 did not affect regardless of the growth phase.
    CONCLUSIONS:
    Appearance and physiological state of S. carnosus LTH1502 cells indicated difference in the way the compounds interacted with and damaged cells. Results were attributed to the different physicochemical properties of RA and its esters.
    Zhongguo Zhong Yao Za Zhi. 2014 Jun;39(12):2284-8.
    [Chemical constituents of Hyptis rhomboidea and their antifungal activity].[Pubmed: 25244760]
    The present work is to investigate the chemical constitutions of Hyptis rhomboidea and their antifungal activities.
    METHODS AND RESULTS:
    The compounds were isolated by Toyopearl HW-40, Sephadex LH-20, MCI-Gel CHP-20, RP-18, PTLC and silica column chromatographic methods and subjected to evaluate some monomers antifungal activity of eight kinds of plant pathogenic bacteria. Eleven compounds were isolated and identified as ethyl caffeate (1), ursolic acid (2), oleanolic acid (3), vanillactic acid (4), Methyl rosmarinate (5), kaempferol 3-O-alpha-L-rhamnopyranosyl-(1 --> 6) -beta-D-glucopyranoside (6), kaempferol 3-O-alpha-L-rhamnopyranosyl-(1 --> 6)-beta-D-glucopyranoside (7), ilexgenin A (8), beta-amyrin (9), kaempferol 3-O-beta-D-glucopyranoside (astrgalin, 10) and cholest-5-ene-3beta, 4beta-diol (11). Compound 1 showed the strongest inhibitory effect on Sclerotinia sclerotiorum with the MIC 16.2 mg x L(-1), and compound 5 showed the strongest inhibitory effect on S. minor and Exserohilum turcicum with MIC 16.2, 8.1 mg x L(-1), respectively.
    CONCLUSIONS:
    All compounds were isolated from the H. rhomboidea for the first time, and compounds 1 and 5 showed antifungal activity.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 2.6709 mL 13.3547 mL 26.7094 mL 53.4188 mL 66.7735 mL
    5 mM 0.5342 mL 2.6709 mL 5.3419 mL 10.6838 mL 13.3547 mL
    10 mM 0.2671 mL 1.3355 mL 2.6709 mL 5.3419 mL 6.6774 mL
    50 mM 0.0534 mL 0.2671 mL 0.5342 mL 1.0684 mL 1.3355 mL
    100 mM 0.0267 mL 0.1335 mL 0.2671 mL 0.5342 mL 0.6677 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    9'''-丹酚酸B单甲酯; 9'''-Methyl salvianolate B CFN90810 1167424-32-9 C37H32O16 = 732.7 20mg QQ客服:2056216494
    丹酚酸B二甲酯; Dimethyl lithospermate B CFN90690 875313-64-7 C38H34O16 = 746.67 20mg QQ客服:1457312923
    丹酚酸E; Salvianolic acid E CFN80272 142998-46-7 C36H30O16 = 718.15 5mg QQ客服:2056216494
    荆芥素A; Schizotenuin A CFN95614 144608-09-3 C36H28O16 = 716.6 10mg QQ客服:215959384
    7'(Z)-(8''R,8'''R)-表-丹酚酸E; 7'(Z)-(8''R,8'''R)-epi-salvianolic acid E CFN80290 N/A C36H30O16 = 718.15 5mg QQ客服:1457312923
    迷迭香酸; Rosmarinic acid CFN99103 20283-92-5 C18H16O8 = 360.31 20mg QQ客服:3257982914
    迷迭香酸甲酯; Methyl rosmarinate CFN97567 99353-00-1 C19H18O8 = 374.4 20mg QQ客服:2159513211
    迷迭香酸-4-氧-葡萄糖苷; Rosmarinyl glucoside CFN95297 910028-78-3 C24H26O13 = 522.5 5mg QQ客服:1457312923
    Clinopodic acid E; Clinopodic acid E CFN95595 159736-38-6 C27H22O12 = 538.5 5mg QQ客服:3257982914
    丹酚酸D; Salvianolic acid D CFN90223 142998-47-8 C20H18O10 = 492.44 5mg QQ客服:215959384

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