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  • 甲基 3-O-阿魏酰奎尼酸酯

    Methyl 3-O-feruloylquinate

    甲基 3-O-阿魏酰奎尼酸酯
    产品编号 CFN92446
    CAS编号 154418-15-2
    分子式 = 分子量 C18H22O9 = 382.4
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Phenylpropanoids
    植物来源 The barks of Phellodendron amurense
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    甲基 3-O-阿魏酰奎尼酸酯 CFN92446 154418-15-2 1mg QQ客服:3257982914
    甲基 3-O-阿魏酰奎尼酸酯 CFN92446 154418-15-2 5mg QQ客服:3257982914
    甲基 3-O-阿魏酰奎尼酸酯 CFN92446 154418-15-2 10mg QQ客服:3257982914
    甲基 3-O-阿魏酰奎尼酸酯 CFN92446 154418-15-2 20mg QQ客服:3257982914
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • Amity University (India)
  • University of Virginia (USA)
  • Kyung Hee University (Korea)
  • Ain Shams University (Egypt)
  • University of Pretoria (South Africa)
  • University of Malaya (Malaysia)
  • Universidad de Antioquia (Colombia)
  • Semmelweis Unicersity (Hungary)
  • Hamdard University (India)
  • Max Rubner-Institut (MRI) (Germany)
  • Copenhagen University (Denmark)
  • Mendel University in Brno (Czech Republic)
  • Shanghai University of TCM (China)
  • Utah State University (USA)
  • More...
  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Natural Product Res.&Deve.2022, 1001-6880.
  • Metabolites2022, 12(6),507.
  • J Ethnopharmacol.2017, 198:87-90
  • Phytomedicine.2022, 96:153877.
  • J Nat Prod.2022, doi: 10.1021
  • Oncotarget.2016, 8(51):88386-88400
  • EXCLI J.2023, 22:482-498.
  • Molecules.2019, 24(6):E1155
  • Nutrients.2018, 10(12)
  • Antioxidants (Basel).2022, 11(12):2496.
  • PLoS One.2018, 13(3):e0193386
  • Chem Biodivers.2023, 20(10):e202300741.
  • Scientific World Journal.2014, 2014:654193
  • Appl. Sci.2020, 10(16),5482.
  • Korean J. Medicinal Crop Sci.2022, 30(2):124-133
  • Front Pharmacol.2019, 10:1025
  • Molecules2022, 27(12):3824.
  • Fitoterapia.2022, 157:105130.
  • J Cell Physiol.2021, 236(3):1950-1966.
  • Appl. Sci. 2021, 11(1),14.
  • J Holistic Integrative Pharm.2023, 4(1):14-28
  • Antioxidants (Basel).2021, 10(9):1435.
  • Trop J Pharm Res.2023, 22(3):283-288.
  • ...
  • 生物活性
    Description: Methyl 3-O-feruloylquinate inhibits the activity of bacteria and viruses and to regulate immunity.
    Targets: Antifection
    In vitro:
    Yao Xue Xue Bao. 2015 Feb;50(2):207-10.
    Chemical constituents of the roots of Macleaya microcarpa and activation efficacy of benzophenanthridine alkaloids for the transcription of xbp1 gene.[Pubmed: 25975030]
    Ongoing study on the chemical constituents of the roots of Macleaya microcarpa led to the isolation of eight compounds of derivatives of triterpenes and organic acids in addition to some previously identified benzophenanthridines.
    METHODS AND RESULTS:
    The eight compounds were identified by spectroscopic methods as well as comparison with literature values as 1-oxo-2, 22 (30)-hopandien-29-oic acid (1), 3-oxo-12-oleanen-30-oic acid (2), 3α-hydroxy-12-oleanen-30-oic acid (3), 3β-hydroxy-12-oleanen-30-oic acid (4), ferulic acid (5), ferulic acid 4-O-β-D-glucoside (6), 3-O-feruloylquinic acid (7), and methyl 3-O-feruloylquinate (8). Of which, 1 is a new triterpenoid of hopanes and 2-8 are isolated from M microcarpa for the first time. In order to discover natural active compounds as potential agents of anti-ulcerative colitis (UC), an in vitro drug high-throughput screening model targeted x-box-binding protein 1 (xbp1) was employed to evaluate the activity of the major chemical constituents of M microcarpa.
    CONCLUSIONS:
    The result confirmed that two dihydrobenzophenanthridines, dihydrosanguinarine (9) and dihydrochelerythrine (10), showed a certain activity on activating the transcription of xbpl, a transcription factor (TF) associated with the occurrence, development, and potential treatment of UC, with their relative activating ratios being 1.76 and 1.77 times, respectively, as compared with control group.
    Biomed Res Int. 2014;2014:761849.
    Possible inhibitor from traditional Chinese medicine for the β form of calcium-dependent protein kinase type II in the treatment of major depressive disorder.[Pubmed: 25045698]
    Recently, an important topic of major depressive disorder (MDD) had been published in 2013. MDD is one of the most prevalent and disabling mental disorders. Consequently, much research is being undertaken into the causes and treatment. It has been found that inhibition of the β form of calcium/calmodulin-dependent protein kinase type II (β-CaMKII) can ameliorate the disorder.
    METHODS AND RESULTS:
    Upon screening the traditional Chinese medicine (TCM) database by molecular docking, sengesterone, labiatic acid, and Methyl 3-O-feruloylquinate were selected for molecular dynamics.
    Biomed Res Int. 2014;2014:635152.
    The inhibition of folylpolyglutamate synthetase (folC) in the prevention of drug resistance in Mycobacterium tuberculosis by traditional Chinese medicine.[Pubmed: 25050369]
    The selected TCM compounds Saussureamine C, Methyl 3-O-feruloylquinate, and Labiatic acid have been found to inhibit the activity of bacteria and viruses and to regulate immunity. We also suggest the possible pathway in protein for each ligand. Compared with the control, similar interactions and structural variations indicate that these compounds might have an effect on Folylpolyglutamate synthetase.
    CONCLUSIONS:
    Finally, we suggest Saussureamine C is the best candidate compound as the complex has a high score, maintains its structural composition, and has a larger variation value than the control, thus inhibiting the drug resistance ability of Mycobacterium tuberculosis.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 2.6151 mL 13.0753 mL 26.1506 mL 52.3013 mL 65.3766 mL
    5 mM 0.523 mL 2.6151 mL 5.2301 mL 10.4603 mL 13.0753 mL
    10 mM 0.2615 mL 1.3075 mL 2.6151 mL 5.2301 mL 6.5377 mL
    50 mM 0.0523 mL 0.2615 mL 0.523 mL 1.046 mL 1.3075 mL
    100 mM 0.0262 mL 0.1308 mL 0.2615 mL 0.523 mL 0.6538 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    5-O-对香豆酰基奎宁酸; 5-O-Coumaroylquinic acid CFN95507 32451-86-8 C16H18O8 = 338.3 5mg QQ客服:2159513211
    新绿原酸; Neochlorogenic acid CFN97472 906-33-2 C16H18O9 = 354.3 20mg QQ客服:2159513211
    新绿原酸甲酯; Neochlorogenic acid methyl ester CFN95190 123410-65-1 C17H20O9 = 368.3 5mg QQ客服:3257982914
    5-O-阿魏酰奎尼酸; 5-O-Feruloylquinic acid CFN92889 40242-06-6 C17H20O9 = 368.3 10mg QQ客服:1413575084
    顺式5-O-阿魏酰奎尼酸; cis-5-O-Feruloylquinic acid CFN95659 87099-75-0 C17H20O9 = 368.3 10mg QQ客服:3257982914
    甲基 5-O-阿魏酰奎尼酸酯; Methyl 5-O-feruloylquinate CFN92445 154461-64-0 C18H22O9 = 382.4 5mg QQ客服:215959384
    绿原酸; Chlorogenic acid CFN99116 327-97-9 C16H18O9 = 354.31 20mg QQ客服:1457312923
    3-咖啡酰奎尼酸甲酯; 3-O-Caffeoylquinic acid methyl ester CFN92573 123483-19-2 C17H20O9 = 368.3 20mg QQ客服:3257982914
    绿原酸乙酯; Ethyl chlorogenate CFN91565 425408-42-0 C18H22O9 = 382.4 5mg QQ客服:3257982914
    3-O-阿魏酰奎尼酸; 3-O-Feruloylquinic acid CFN92393 1899-29-2 C17H20O9 = 368.3 5mg QQ客服:3257982914

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