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  • 厚朴苷A

    Magnoloside A

    厚朴苷A
    产品编号 CFN99232
    CAS编号 113557-95-2
    分子式 = 分子量 C29H36O15 = 624.6
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Phenylpropanoids
    植物来源 The barks of Magnolia obovata.
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    厚朴苷A CFN99232 113557-95-2 1mg QQ客服:2056216494
    厚朴苷A CFN99232 113557-95-2 5mg QQ客服:2056216494
    厚朴苷A CFN99232 113557-95-2 10mg QQ客服:2056216494
    厚朴苷A CFN99232 113557-95-2 20mg QQ客服:2056216494
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • MTT Agrifood Research Finland (Finland)
  • Yale University (USA)
  • Uniwersytet Medyczny w ?odzi (Poland)
  • Heinrich-Heine-University Düsseldorf (Germany)
  • University of Maryland School of Medicine (USA)
  • University of Sao Paulo (Brazil)
  • Johannes Gutenberg University Mainz (JGU) (Germany)
  • Wageningen University (Netherlands)
  • Universidad de Buenos Aires (Argentina)
  • University of Cincinnati (USA)
  • Universidad Miguel Hernández (Spain)
  • University of Maryland (USA)
  • Michigan State University (USA)
  • Amity University (India)
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  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Eur J Pharmacol.2020, 889:173589.
  • PLoS One.2018, 13(3):e0193386
  • Biomed Sci Letters.2020, 26:319-326
  • Vietnam Journal of Food Control.2022, 5(3):pp.488-497.
  • J Agric Food Chem.2021, 69(46):14037-14047.
  • BMC Plant Biol.2022, 22(1):128.
  • Tropical Journal of Pharmaceutical Research 2021, 20(6):1165-1170.
  • Plant Cell Tiss Org2020, 1-16
  • Int J Pharmacol2020, 16:1-9
  • The Journal of Agromedicine and Medical Sciences2018, 4(1)
  • J of Pharmaceutical Analysis2020, doi: 10.1016
  • Plants (Basel).2020, 9(11):1422.
  • Pol J Microbiol.2021, 70(1):117-130.
  • Antioxidants.2022, 11(4), 67.
  • GxABT2022, 2268.2:15515.
  • Toxicological Research2020, doi: 10.1007.
  • Tea Res. Ins. Of China2017, 1-12
  • PLoS One.2021, 16(6):e0248479.
  • Virulence.2018, 9(1):588-603
  • J Ethnopharmacol.2019, 235:406-414
  • Pak J Pharm Sci.2019, 32(6):2879-2885
  • Enzyme Microb Technol.2022, 153:109941.
  • Antioxidants (Basel).2022, 11(12):2411.
  • ...
  • 生物活性
    Description: Magnoloside A has potent antifungal activities against various Cryptococcus strains with minimum inhibitory concentration values ranging from 1.0 to 4.0 ug/ml.
    Targets: Antifection
    In vitro:
    J Microbiol Biotechnol. 2015 Sep;25(9):1429-32.
    A Phenylpropanoid Glycoside as a Calcineurin Inhibitor Isolated from Magnolia obovata Thunb.[Pubmed: 26174771 ]

    METHODS AND RESULTS:
    To identify plant-derived cell signaling inhibitors with antifungal properties, a twocomponent screening system using both wild-type Cryptococcus neoformans and a calcineurin mutant was employed owing to their counter-regulatory actions on the Hog1 mitogenactivated protein kinase and calcineurin pathways. Of the 2,000 plant extracts evaluated, a single bioactive compound from M. obovata Thunb. was found to act specifically on the calcineurin pathway of C. neoformans.
    CONCLUSIONS:
    This compound was identified as magnoloside A, and had potent antifungal activities against various Cryptococcus strains with minimum inhibitory concentration values ranging from 1.0 to 4.0 μg/ml.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 1.601 mL 8.0051 mL 16.0102 mL 32.0205 mL 40.0256 mL
    5 mM 0.3202 mL 1.601 mL 3.202 mL 6.4041 mL 8.0051 mL
    10 mM 0.1601 mL 0.8005 mL 1.601 mL 3.202 mL 4.0026 mL
    50 mM 0.032 mL 0.1601 mL 0.3202 mL 0.6404 mL 0.8005 mL
    100 mM 0.016 mL 0.0801 mL 0.1601 mL 0.3202 mL 0.4003 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    大车前苷; Plantamajoside CFN99522 104777-68-6 C29H36O16 = 640.6 20mg QQ客服:1457312923
    车前草苷D; Plantainoside D CFN93188 147331-98-4 C29H36O16 = 640.59 10mg QQ客服:2159513211
    贞桐苷A; Clerodenoside A CFN99691 164022-75-7 C35H44O17 = 736.7 5mg QQ客服:2159513211
    鞭打绣球苷A; Hemiphroside A CFN99697 165338-27-2 C31H40O16 = 668.7 5mg QQ客服:3257982914
    鞭打绣球苷B; Hemiphroside B CFN99698 165338-28-3 C31H38O17 = 682.6 5mg QQ客服:1413575084
    鞭打绣球苷B十乙酰酯; Hemiphroside B nonaacetate CFN89035 132302-25-1 C49H56O26 = 1060.98 5mg QQ客服:1413575084
    连翘酯苷A; Forsythoside A CFN99705 79916-77-1 C29H36O15 = 624.59 20mg QQ客服:1457312923
    连翘酯苷I; Forsythoside I CFN90988 1177581-50-8 C29H36O15 = 624.59 10mg QQ客服:1457312923
    细叶远志苷 A; Tenuifoliside A CFN90770 139726-35-5 C31H38O17 = 682.6 20mg QQ客服:2159513211
    3,6-二芥子酰基蔗糖; 3,6'-Disinapoyl sucrose CFN90578 139891-98-8 C34H42O19 = 754.68 20mg QQ客服:2056216494

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