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  • 厚朴苷A

    Magnoloside A

    厚朴苷A
    产品编号 CFN99232
    CAS编号 113557-95-2
    分子式 = 分子量 C29H36O15 = 624.6
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Phenylpropanoids
    植物来源 The barks of Magnolia obovata.
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    厚朴苷A CFN99232 113557-95-2 1mg QQ客服:215959384
    厚朴苷A CFN99232 113557-95-2 5mg QQ客服:215959384
    厚朴苷A CFN99232 113557-95-2 10mg QQ客服:215959384
    厚朴苷A CFN99232 113557-95-2 20mg QQ客服:215959384
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • Charles Sturt University (Denmark)
  • Universidade Federal de Santa Catarina (Brazil)
  • University of Vienna (Austria)
  • Univerzita Karlova v Praze (Czech Republic)
  • Melbourne University (Australia)
  • The Vancouver Prostate Centre (VPC) (Canada)
  • University of Lodz (Poland)
  • University of Wuerzburg (Germany)
  • Research Unit Molecular Epigenetics (MEG) (Germany)
  • Universiti Kebangsaan Malaysia (Malaysia)
  • University of Parma (Italy)
  • Centralised Purchases Unit (CPU), B.I.T.S (India)
  • University Medical Center Mainz (Germany)
  • Korea Intitute of Science and Technology (KIST) (Korea)
  • More...
  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Acta Agriculturae Scandinavica2015, 381-383
  • Biomed Chromatogr.2016, 30(10):1573-81
  • Phytother Res.2016, 30(12):2020-2026
  • J Exp Bot.2016, 67(12):3777-88
  • Planta Med.2016, 82(13):1208-16
  • Molecular & Cellular Toxicology2017, 13(3):271-278
  • J Agric Food Chem.2017, 65(13):2670-2676
  • Cell.2018, 172(1-2):249-261
  • Food Chem.2018, 252:207-214
  • Journal of Third Military Medical University2018, 40(12):1073-1078
  • Cell Death Dis.2019, 10(12):882
  • J Cancer.2019, 10(23):5843-5851
  • Nutrients.2019, 12(1):E40
  • Industrial Crops and Products2019, 140:111612
  • BMC Complement Altern Med.2019, 19(1):11
  • Molecules.2019, 24(6):E1155
  • Phytomedicine.2019, 58:152893
  • Phytomedicine.2019, 59:152785
  • Environ Toxicol Pharmacol.2019, 66:109-115
  • J Nat Prod.2019, 82(4):1002-1008
  • Genes Genomics.2020, 10.1007
  • Psychopharmacology (Berl).2020, 10.1007
  • Plant Foods Hum Nutr.2020, 10.1007
  • ...
  • 生物活性
    Description: Magnoloside A has potent antifungal activities against various Cryptococcus strains with minimum inhibitory concentration values ranging from 1.0 to 4.0 ug/ml.
    Targets: Antifection
    In vitro:
    J Microbiol Biotechnol. 2015 Sep;25(9):1429-32.
    A Phenylpropanoid Glycoside as a Calcineurin Inhibitor Isolated from Magnolia obovata Thunb.[Pubmed: 26174771 ]

    METHODS AND RESULTS:
    To identify plant-derived cell signaling inhibitors with antifungal properties, a twocomponent screening system using both wild-type Cryptococcus neoformans and a calcineurin mutant was employed owing to their counter-regulatory actions on the Hog1 mitogenactivated protein kinase and calcineurin pathways. Of the 2,000 plant extracts evaluated, a single bioactive compound from M. obovata Thunb. was found to act specifically on the calcineurin pathway of C. neoformans.
    CONCLUSIONS:
    This compound was identified as magnoloside A, and had potent antifungal activities against various Cryptococcus strains with minimum inhibitory concentration values ranging from 1.0 to 4.0 μg/ml.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 1.601 mL 8.0051 mL 16.0102 mL 32.0205 mL 40.0256 mL
    5 mM 0.3202 mL 1.601 mL 3.202 mL 6.4041 mL 8.0051 mL
    10 mM 0.1601 mL 0.8005 mL 1.601 mL 3.202 mL 4.0026 mL
    50 mM 0.032 mL 0.1601 mL 0.3202 mL 0.6404 mL 0.8005 mL
    100 mM 0.016 mL 0.0801 mL 0.1601 mL 0.3202 mL 0.4003 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    鞭打绣球苷B十乙酰酯; Hemiphroside B nonaacetate CFN89035 132302-25-1 C49H56O26 = 1060.98 5mg QQ客服:215959384
    连翘酯苷A; Forsythoside A CFN99705 79916-77-1 C29H36O15 = 624.59 20mg QQ客服:215959384
    连翘酯苷I; Forsythoside I CFN90988 1177581-50-8 C29H36O15 = 624.59 5mg QQ客服:215959384
    细叶远志苷 A; Tenuifoliside A CFN90770 139726-35-5 C31H38O17 = 682.6 20mg QQ客服:215959384
    3,6-二芥子酰基蔗糖; 3,6'-Disinapoyl sucrose CFN90578 139891-98-8 C34H42O19 = 754.68 20mg QQ客服:1413575084
    3-阿魏酸酯-1-芥子酰基蔗糖; 3-Feruloyl-1-Sinapoyl sucrose CFN93305 98942-06-4 C33H40O18 = 724.66 5mg QQ客服:1148253675
    毛蕊花糖苷; 麦角甾苷; Acteoside CFN97048 61276-17-3 C29H36O15 = 624.6 20mg QQ客服:1148253675
    2'-乙酰基毛蕊花糖苷; 2'-Acetylacteoside CFN92452 94492-24-7 C31H38O16 = 666.6 20mg QQ客服:1148253675
    异麦角甾苷; Isoacteoside CFN97049 61303-13-7 C29H36O15 = 624.6 20mg QQ客服:215959384
    厚朴苷D; Magnoloside D CFN91910 1418309-03-1 C29H36O15 = 624.59 5mg QQ客服:3257982914

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