Info: Read More
  • 中药标准品生产商,产品定制服务
  • 木犀草素 5-葡萄糖苷

    Luteollin 5-glucoside

    木犀草素 5-葡萄糖苷
    产品编号 CFN98568
    CAS编号 20344-46-1
    分子式 = 分子量 C21H20O11 = 448.38
    产品纯度 >=98%
    物理属性 Yellow powder
    化合物类型 Flavonoids
    植物来源 The herbs of Dracocephalum ruyschiana L.
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    木犀草素 5-葡萄糖苷 CFN98568 20344-46-1 1mg QQ客服:3257982914
    木犀草素 5-葡萄糖苷 CFN98568 20344-46-1 5mg QQ客服:3257982914
    木犀草素 5-葡萄糖苷 CFN98568 20344-46-1 10mg QQ客服:3257982914
    木犀草素 5-葡萄糖苷 CFN98568 20344-46-1 20mg QQ客服:3257982914
    存储与注意事项
    1. 在您收到产品后请检查产品。如无问题,请将产品存入冰霜并且样品瓶保持密封,产品可以存放长达24个月(2-8摄氏度)。

    2. 只要有可能,产品溶解后,您应该在同一天应用于您的实验。 但是,如果您需要提前做预实验,或者需要全部溶解,我们建议您将溶液以等分试样的形式存放在-20℃的密封小瓶中。 通常,这些可用于长达两周。 使用前,打开样品瓶前,我们建议您将产品平衡至室温至少1小时。

    3. 需要更多关于溶解度,使用和处理的建议? 请发送电子邮件至:service@chemfaces.com
    订购流程
  • 1. 在线订购
  • 请联系我们QQ客服

  • 2. 电话订购
  • 请拨打电话:
    027-84237683 或 027-84237783

  • 3. 邮件或传真订购
  • 发送电子邮件到: manager@chemfaces.com 或
    发送传真到:027-84254680

  • 提供订购信息
  • 为了方便客户的订购,请需要订购ChemFaces产品的客户,在下单的时候请提供下列信息,以供我们快速为您建立发货信息。
  •  
  • 1. 产品编号(CAS No.或产品名称)
  • 2. 发货地址
  • 3. 联系方法 (联系人,电话)
  • 4. 开票抬头 (如果需要发票的客户)
  • 5. 发票地址(发货地址与发票地址不同)
  • 发货时间
    1. 付款方式为100%预付款客户,我们将在确认收到货款后当天或1-3个工作日发货。

    2. 付款方式为月结的客户,我们承诺在收到订单后当天或1-3个工作日内发货。

    3. 如果客户所需要的产品,需要重新生产,我们有权告知客户,交货时间需要延期。
    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • Technical University of Denmark (Denmark)
  • China Medical University (Taiwan)
  • Universidad Veracuzana (Mexico)
  • Leibniz-Institut für Pflanzenbiochemie (IPB) (Germany)
  • Sapienza University of Rome (Italy)
  • Universidade Federal de Pernambuco (UFPE) (Brazil)
  • University of Oslo (Norway)
  • Instituto Politécnico de Bragan?a (Portugal)
  • University of Toronto (Canada)
  • The Ohio State University (USA)
  • Michigan State University (USA)
  • Center for protein Engineering (CIP) (Belgium)
  • CSIRO - Agriculture Flagship (Australia)
  • Universitas Airlangga (Indonesia)
  • More...
  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • The Korea Journal of Herbology2016, 29-35
  • Cancers (Basel).2023, 15(1):37.
  • J of Essential Oil Research2019, 1677272
  • Int J Mol Sci.2020, 21(9):3392.
  • J Sep Sci.2022, 45(18):3556-3566.
  • Preprints2021, doi:10.20944
  • The Korea Society of Pha.2014, 300-314
  • Curr Issues Mol Biol.2023, 45(3):2136-2156.
  • Research Square2022, rs.3.rs-1948239
  • J Mol Recognit.2020, 33(2):e2819
  • Chem Biol Interact.2022, 368:110248.
  • Phytomedicine.2021, 93:153789.
  • Int J Nanomedicine.2022, 17:6513-6525.
  • Academic J of Second Military Medical University2018, 39(11)
  • Mol Med Rep.2015, 12(5):7789-95
  • Jour. of Stored Pro & Postharvest Res.2016, 7(3):32-36
  • Int Immunopharmacol.2020, 90:107268.
  • New Zealand J. Forestry Sci.2014, 44:17
  • Universidade Estadual Paulista2017, 11449
  • BMC Complement Med Ther.2023, 23(1):264.
  • J Funct Foods2019, 54:449-456
  • Nat Commun.2023, 14(1):4540.
  • Chemistry of Natural Compounds2020, 56,423-426
  • ...
  • 生物活性
    Description: Luteolin 5-O-β-glucopyranoside has antioxidant activity, it can inhibit lipid peroxidation, and has DPPH radical-scavenging activity.
    In vitro:
    Appl Environ Microbiol. 2003 Oct;69(10):5849-54.
    Anaerobic degradation of flavonoids by Clostridium orbiscindens.[Pubmed: 14532034]

    METHODS AND RESULTS:
    An anaerobic, quercetin-degrading bacterium was isolated from human feces and identified as Clostridium orbiscindens by comparative 16S rRNA gene sequence analysis. The organism was tested for its ability to transform several flavonoids. The isolated C. orbiscindens strain converted quercetin and taxifolin to 3,4-dihydroxyphenylacetic acid; luteolin and eriodictyol to 3-(3,4-dihydroxyphenyl)propionic acid; and apigenin, naringenin, and phloretin to 3-(4-hydroxyphenyl)propionic acid, respectively. Genistein and daidzein were not utilized.
    CONCLUSIONS:
    The glycosidic bonds of luteolin-3-glucoside, Luteollin 5-glucoside, naringenin-7-neohesperidoside (naringin), quercetin-3-glucoside, quercetin-3-rutinoside (rutin), and phloretin-2'-glucoside were not cleaved.
    Planta Med., 2011, 13(5):1-12.
    Relationship between chemical structure and antioxidant activity of luteolin and its glycosides isolated from thymus sipyleus subsp. sipyleus var. sipyleus.[Reference: WebLink]
    One triterpenic acid (ursolic acid), one phenolic acid (rosmarinic acid), and four flavonoids (luteolin, luteolin 7-O-(6"-feruloyl)-β-glucopyranoside, luteolin 5-O-β-glucopyranoside(Luteollin 5-glucoside ), and luteolin 7-O-β-glucuronide) were isolated from the aerial parts of Thymus sipyleus subsp. sipyleus var. sipyleus and identified by spectroscopic methods.
    METHODS AND RESULTS:
    In vitro lipid peroxidation inhibition effects of the compounds were determined using TBA test method in a bovine brain liposome system. All compounds inhibited lipid peroxidation in various degrees except for ursolic acid. The order of the lipid peroxidation activities of luteolin, its glycosides and rosmarinic acid were: Luteolin 7-O-β-glucuronide> luteolin 5-O-β-glucopyranoside(Luteollin 5-glucoside )> luteolin 7-O-(6"-feruloyl)- β-glucopyranoside > rosmarinic acid >luteolin. However, the activity order of the compounds was completely different in DPPH radical-scavenging activity. None of the compounds shows Fe 2+ chelating activity. The results were discussed based on their chemical structures and polarities.
    Food Chem Toxicol . 2012 Jun;50(6):2171-9.
    Anti-inflammatory activity of Korean thistle Cirsium maackii and its major flavonoid, luteolin 5-O-glucoside[Pubmed: 22525859]
    Abstract The anti-inflammatory activity of whole Cirsium maackii (family Compositae) plants and of its major flavonoid, luteolin 5-O-glucoside, was evaluated for their ability to inhibit lipopolysaccharide (LPS)-induced nitric oxide (NO) production, inducible nitric oxide synthase (iNOS), cyclooxygenase-2 (COX-2) protein expression, and tert-butylhydroperoxide (t-BHP)-induced reactive oxygen species (ROS) generation in RAW 264.7 murine macrophage cells. The methanolic extract of C. maackii showed strong anti-inflammatory activity, and was thus fractionated with several solvents. The ethyl acetate-soluble fraction, exhibiting the highest anti-inflammatory activity potential, was further to yield a major flavonoid, luteolin 5-O-glucoside. We found that luteolin 5-O-glucoside, at a non-toxic concentration, inhibited LPS-induced NO production and t-BHP-induced ROS generation in a dose-dependent manner in RAW 264.7 cells. It also suppressed the expression of iNOS and COX-2 in LPS-stimulated macrophages. Furthermore, the efficacies of the methanolic extract of C. maackii in inhibiting both NO and ROS were attributed to its flavonoid content by HPLC analysis. These results indicated that C. maackii whole plants and its flavonoids inhibit the expression of iNOS and COX-2 in through the inhibition of ROS generation, and therefore can be considered as a useful therapeutic and preventive approach for the treatment of various inflammatory and oxidative stress-related diseases. Copyright © 2012 Elsevier Ltd. All rights reserved.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 2.2303 mL 11.1513 mL 22.3025 mL 44.605 mL 55.7563 mL
    5 mM 0.4461 mL 2.2303 mL 4.4605 mL 8.921 mL 11.1513 mL
    10 mM 0.223 mL 1.1151 mL 2.2303 mL 4.4605 mL 5.5756 mL
    50 mM 0.0446 mL 0.223 mL 0.4461 mL 0.8921 mL 1.1151 mL
    100 mM 0.0223 mL 0.1115 mL 0.223 mL 0.4461 mL 0.5576 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    5-羟基-7,8,2',5'-四甲氧基黄酮 5-O-葡萄糖苷; 5-Hydroxy-7,8,2',5'-tetramethoxyflavone 5-O-glucoside CFN97595 942626-75-7 C25H28O12 = 520.49 5mg QQ客服:3257982914
    木犀草苷; 木犀草素-7-O-葡萄糖苷; Luteolin-7-O-glucoside CFN98565 5373-11-5 C21H20O11 = 448.38 20mg QQ客服:2056216494
    木犀草素-7-O-葡萄糖醛酸苷; Luteolin-7-O-glucuronide CFN98512 29741-10-4 C21H18O12 = 462.36 20mg QQ客服:1457312923
    忍冬苷; Lonicerin CFN95055 25694-72-8 C27H30O15 = 594.5 10mg QQ客服:2056216494
    木犀草素 7-芸香糖苷; Luteolin 7-rutinoside CFN93556 20633-84-5 C27H30O15 = 594.52 20mg QQ客服:215959384
    木犀草素 5-葡萄糖苷; Luteollin 5-glucoside CFN98568 20344-46-1 C21H20O11 = 448.38 5mg QQ客服:3257982914
    芫花叶苷; Yuanhuanin CFN95127 83133-14-6 C22H22O11 = 462.4 5mg QQ客服:215959384
    芫花素-5-O-茜黄苷; Yuankanin CFN95128 77099-20-8 C27H30O14 = 578.5 5mg QQ客服:215959384
    木犀草素-3'-葡萄糖醛酸苷; Luteolin-3-O-beta-D-glucuronide CFN93187 53527-42-7 C21H18O12 = 462.4 10mg QQ客服:2056216494
    木犀草素-7-二葡萄糖苷酸; Luteolin 7-diglucuronide CFN70468 96400-45-2 C27H26O18 = 638.5 5mg QQ客服:215959384

    信息支持


    公司简介
    订购流程
    付款方式
    退换货政策

    ChemFaces提供的产品仅用于科学研究使用,不用于诊断或治疗程序。

    联系方式


    电机:027-84237783
    传真:027-84254680
    在线QQ: 1413575084
    E-Mail:manager@chemfaces.com

    湖北省武汉沌口经济技术开区车城南路83号1号楼第三层厂房


    ChemFaces为科学家,科研人员与企业提供快速的产品递送。我们通过瑞士SGS ISO 9001:2008质量体系认证天然化合物与对照品的研发和生产