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  • 木犀草素-3',7-di-O-葡萄糖苷

    Luteolin-3',7-di-O-glucoside

    木犀草素-3',7-di-O-葡萄糖苷
    产品编号 CFN93558
    CAS编号 52187-80-1
    分子式 = 分子量 C27H30O16 = 610.52
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Flavonoids
    植物来源 The leaves of Markhamia tomentosa.
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    木犀草素-3',7-di-O-葡萄糖苷 CFN93558 52187-80-1 1mg QQ客服:1457312923
    木犀草素-3',7-di-O-葡萄糖苷 CFN93558 52187-80-1 5mg QQ客服:1457312923
    木犀草素-3',7-di-O-葡萄糖苷 CFN93558 52187-80-1 10mg QQ客服:1457312923
    木犀草素-3',7-di-O-葡萄糖苷 CFN93558 52187-80-1 20mg QQ客服:1457312923
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • VIT University (India)
  • Instituto Politécnico de Bragan?a (Portugal)
  • Institute of Bioorganic Chemistry Polish Academy of Sciences (Poland)
  • University of Hawaii Cancer Center (USA)
  • University of Beira Interior (Portugal)
  • Kamphaengphet Rajabhat University (Thailand)
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  • Universidade de Franca (Brazil)
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  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • PLoS One.2015, 10(5):e0127060
  • Nature Ecology & Evolution2020, doi: 10.1038
  • Arch Biochem Biophys.2018, 644:93-99
  • J Agric Food Chem.2020, 68(43):12164-12172.
  • Integr Med Res.2021, 10(3):100723.
  • Front Pharmacol.2018, 9:756
  • J.Pharm. & Biome. Anal.2023, 2: 100018.
  • Current Traditional Medicine, 2021, 7:326-335(10).
  • Natural Product Res.&Deve.2022, 1001-6880.
  • J Anal Methods Chem.2022, 2022:2229500.
  • Front Aging Neurosci.2019, 11:230
  • Int J Mol Sci.2022, 23(21):12816.
  • Food Quality and Safety2018, 2:213-219
  • J Agric Food Chem.2021, 69(11):3496-3510.
  • Univerzita Karlova2022, 173245.
  • Appl. Sci.2020, 10(4),1304
  • Archives of Biological sciences2022, 00:21-21
  • Cells.2022, 11(8), 1311.
  • South African J of Botany2020, 135:50-57
  • Environ Toxicol.2023, 38(5):1174-1184.
  • Chemistry of Natural Compounds2019, 55(1):127-130
  • Asian J Beauty Cosmetol2019, 17(3):287-294
  • Separations2021, 8(7),90.
  • ...
  • 生物活性
    Description: Luteolin-3',7-di-O-glucoside has anti-ulcer and antioxidant activities.
    In vitro:
    Nat Prod Res. 2015;29(17):1673-7.
    Antioxidant activities and quali-quantitative analysis of different Smallanthus sonchifolius [(Poepp. and Endl.) H. Robinson] landrace extracts.[Pubmed: 25533266 ]
    Five landraces of Smallanthus sonchifolius [(Poepp. and Endl.) H. Robinson], known as yacon, were investigated in total phenolic content, antioxidant activity and chemical composition of ethanol extracts (EEs) and decoction extracts (DEs).
    METHODS AND RESULTS:
    The results demonstrated that DEs are rich in phenolic acids as caffeic acid, while the EEs show an higher amount of flavonoids, as luteolin 3',7-O-diglucoside and luteolin 7-O-glucoside. These flavonoid glycosides were identified for the first time in yacon extracts, together with apigenin and luteolin. The phytochemical profile explains the different antioxidant activities shown in our study.
    CONCLUSIONS:
    The landraces PER6-DE and PER4-DE showed the highest radical-scavenging activity and reducing power related to their polyphenolic contents. Results also show that yacon can be considered an important source of bioactive compounds with significant differences among the analysed landraces.
    In vivo:
    J Ethnopharmacol. 2014 Nov 18;157:1-6.
    Antiulcer activity of the ethanolic extract and ethyl acetate fraction of the leaves of Markhamia tomentosa in rats.[Pubmed: 25240588]
    The leaves of Markhamia tomentosa (Benth.) K. Schum. Ex Engl. (Bignoniaceae) are used traditionally in the treatment of skin afflictions, sores, ulcers and inflammation. The aim of the study was to investigate the antiulcer activity of the crude ethanolic extract from the leaves of Markhamia tomentosa, determine the active fraction(s) of the extract and identify the chemical constituents in the active fraction by LC-MS.
    METHODS AND RESULTS:
    The antiulcer activity of the crude extract (50, 100 and 150mg/kg, p.o.) was evaluated in ethanol and indomethacin-induced models while the solvent fractions (150mg/kg) were screened using ethanol-induced gastric lesions in rats. Furthermore, anti-ulcer activity of the active fraction (50, 100 and 150mg/kg, p.o.) was performed using indomethacin and pylorus ligation models. Parameters such as gastric volume, pH and acidity were determined in the pylorus ligation model. LC-ESI-MS analysis was used to identify the components in the active fraction. The extract at the dose of 50, 100 and 150mg/kg caused a significant (p<0.05) dose-dependent inhibition of ulcer in the ethanol and indomethacin-induced ulcer models, respectively. The ethyl acetate (EtOAc) fraction showed the most potent antiulcer activity from all the fractions tested. This fraction produced 72% and 92% inhibition of indomethacin and pylorus-induced ulcer at a dose of 150mg/kg respectively. Acteoside, luteolin, luteolin-7-rutinoside, Luteolin-3',7-di-O-glucoside, carnosol, dilapachone, tormentic acid, oxo-pomolic acid and ajugol were detected in the EtOAc fraction.
    CONCLUSIONS:
    Our data provide a rational base for the folkloric use of Markhamia tormentosa in the treatment of ulcers.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 1.6379 mL 8.1897 mL 16.3795 mL 32.759 mL 40.9487 mL
    5 mM 0.3276 mL 1.6379 mL 3.2759 mL 6.5518 mL 8.1897 mL
    10 mM 0.1638 mL 0.819 mL 1.6379 mL 3.2759 mL 4.0949 mL
    50 mM 0.0328 mL 0.1638 mL 0.3276 mL 0.6552 mL 0.819 mL
    100 mM 0.0164 mL 0.0819 mL 0.1638 mL 0.3276 mL 0.4095 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    麻黄宁E; Mahuannin E CFN95585 1173887-70-1 C30H24O9 = 528.5 5mg QQ客服:1413575084
    瓜子金皂苷己; Polygalasaponin F CFN90171 882664-74-6 C53H86O23 = 1091.3 20mg QQ客服:215959384
    (±)-松属素; (+/-)-Pinocembrin CFN92629 68745-38-0 C15H12O4 = 256.3 5mg QQ客服:1457312923
    5,3'-二羟基-6,7,4',5'-四甲氧基黄酮; 3',5-Dihydroxy-4',5',6,7-tetramethoxyflavone CFN99214 111537-41-8 C19H18O8 = 374.4 5mg QQ客服:1413575084

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