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  • Lucidal

    Lucidal

    Lucidal
    产品编号 CFN92234
    CAS编号 252351-96-5
    分子式 = 分子量 C30H46O3 = 454.7
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Triterpenoids
    植物来源 The fruit body of Ganoderma lucidum
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    Lucidal CFN92234 252351-96-5 1mg QQ客服:1148253675
    Lucidal CFN92234 252351-96-5 5mg QQ客服:1148253675
    Lucidal CFN92234 252351-96-5 10mg QQ客服:1148253675
    Lucidal CFN92234 252351-96-5 20mg QQ客服:1148253675
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • National Research Council of Canada (Canada)
  • Universidade de Franca (Brazil)
  • University of Mysore (India)
  • Semmelweis Unicersity (Hungary)
  • Complutense University of Madrid (Spain)
  • Mahidol University (Thailand)
  • Institute of Tropical Disease Universitas Airlangga (Indonesia)
  • VIT University (India)
  • Sri Ramachandra University (India)
  • Uniwersytet Jagielloński w Krakowie (Poland)
  • University of Bordeaux (France)
  • Anna University (India)
  • Aveiro University (Portugal)
  • Universite de Lille1 (France)
  • More...
  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • BMC Complement Altern Med.2014, 14:352
  • Food Science and Biotechnology2015, 2205-2212
  • Inflammation.2015, 38(4):1502-16
  • Korean J. of Food Sci. and Tech2016, 172-177
  • Food Chem.2016, 191:81-90
  • J Chromatogr B Analyt Technol Biomed Life Sci. 2017, 1064:115-123
  • Biochem Pharmacol.2017, 130:10-20
  • Research on Crops.2017, 18(3):569
  • Pharmacol Rep.2017, 69(6):1224-1231
  • J of Engineering Science&Technology2018, 13(9):2820-2828
  • Molecules.2018, 23(3):E615
  • J Sep Sci.2018, 41(7):1682-1690
  • J Nat Med.2018, 72(3):734-744
  • Journal of Life Science2018, 917-922
  • Neuropharmacology2019, 151437
  • Spectrochim Acta A2019, 210:372-380
  • J Ethnopharmacol.2019, 228:132-141
  • Molecules.2019, 24(11):E2102
  • Molecules.2019, 24(16):E3003
  • Toxicol Res.2019, 35(4):371-387
  • Biochem Biophys Res Commun.2019, 518(4):732-738
  • Int J Oncol.2019, 55(1):320-330
  • Drug Des Devel Ther.2020, 14:61-71
  • ...
  • 生物活性
    Description: Lucialdehyde C (Lucidal) exhibits potent cytotoxicity against LLC, T-47D, Sarcoma 180, and Meth-A tumor cells with ED(50) values of 10.7, 4.7, 7.1, and 3.8 microg/ml, respectively.
    In vitro:
    Cheminform, 2010, 33(48):837-40.
    New Triterpene Aldehydes, Lucialdehydes AC, from Ganoderma lucidum and Their Cytotoxicity Against Murine and Human Tumor Cells[Reference: WebLink]

    METHODS AND RESULTS:
    Three new lanostante-type triterpene aldehydes, named lucialdehydes A-C (1-3), were isolated from the fruiting bodies of Ganoderma lucidum, together with ganodermanonol (4), ganodermadiol (5), ganodermanondiol (6), ganodermanontriol (7), ganoderic acid A (8), ganoderic acid B8 (9), and ganoderic acid C1 (10). The structures of the new triterpenes were determined as (24E)-3 beta-hydroxy-5 alpha-lanosta-7,9(11),24-trien-26-al (1), (24E)-3,7-dioxo-5 alpha-lanosta-8,24-dien-26-al (2), and (24E)-3 beta-hydroxy-7-oxo-5 alpha-lanosta-8,24-dien-26-al (3), respectively, by spectroscopic means. The cytotoxicity of the compounds isolated from the ganoderma mushroom was tested in vitro against Lewis lung carcinoma (LLC), T-47D, Sarcoma 180, and Meth-A tumor cell lines.
    CONCLUSIONS:
    Lucialdehydes B, C (2, 3), ganodermanonol (4) and ganodermanondiol (6) showed cytotoxic effects on tested tumor cells. Of the compounds, lucialdehyde C ((Lucidal,3) exhibited the most potent cytotoxicity against LLC, T-47D, Sarcoma 180, and Meth-A tumor cells with ED(50) values of 10.7, 4.7, 7.1, and 3.8 microg/ml, respectively.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 2.1993 mL 10.9963 mL 21.9925 mL 43.985 mL 54.9813 mL
    5 mM 0.4399 mL 2.1993 mL 4.3985 mL 8.797 mL 10.9963 mL
    10 mM 0.2199 mL 1.0996 mL 2.1993 mL 4.3985 mL 5.4981 mL
    50 mM 0.044 mL 0.2199 mL 0.4399 mL 0.8797 mL 1.0996 mL
    100 mM 0.022 mL 0.11 mL 0.2199 mL 0.4399 mL 0.5498 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    Lucialdehyde B; Lucialdehyde B CFN90305 480439-84-7 C30H44O3 = 452.67 5mg QQ客服:2159513211
    Lucidumol A; Lucidumol A CFN95059 217476-73-8 C30H48O4 = 472.7 5mg QQ客服:215959384
    灵芝醇A; Ganoderol A CFN99065 104700-97-2 C30H46O2 = 438.7 5mg QQ客服:215959384
    灵芝醇F; Ganoderiol F CFN99244 114567-47-4 C30H46O3 = 454.7 5mg QQ客服:1148253675
    灵芝萜酮二醇 ; Ganodermanondiol CFN99085 107900-76-5 C30H48O3 = 456.7 5mg QQ客服:215959384
    灵芝醇A; Ganoderiol A CFN80461 106518-61-0 C30H50O4 = 474.37 5mg QQ客服:3257982914
    灵芝马酮; Ganodermanontriol CFN99077 106518-63-2 C30H48O4 = 472.7 5mg QQ客服:215959384
    Lucialdehyde A; Lucialdehyde A CFN90304 420781-84-6 C30H46O2 = 438.69 5mg QQ客服:215959384
    灵芝醛A; Ganoderal A CFN90306 104700-98-3 C30H44O2 = 436.68 5mg QQ客服:2932563308
    灵芝酮A; Ganoderone A CFN90303 873061-79-1 C30H48O3 = 456.70 5mg QQ客服:2159513211

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