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  • 甘松香酮 A

    Kanshone A

    甘松香酮 A
    产品编号 CFN96977
    CAS编号 115356-18-8
    分子式 = 分子量 C15H22O2 = 234.33
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Sesquiterpenoids
    植物来源 The rhizomes and roots of Nardostachys chinensis.
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    甘松香酮 A CFN96977 115356-18-8 1mg QQ客服:2159513211
    甘松香酮 A CFN96977 115356-18-8 5mg QQ客服:2159513211
    甘松香酮 A CFN96977 115356-18-8 10mg QQ客服:2159513211
    甘松香酮 A CFN96977 115356-18-8 20mg QQ客服:2159513211
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
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  • The University of Newcastle (Australia)
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  • Worcester Polytechnic Institute (USA)
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  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Int J Mol Sci.2020, 21(9):3144.
  • Int J Mol Sci.2021, 22(19):10220.
  • Cell Biochem Funct.2018, 36(6):303-311
  • In Vitro Cellular & Developmental Biology - Plant2022, 58:972-988.
  • Front Plant Sci.2017, 8:723
  • Front Pharmacol.2022, 13:806869.
  • Food Research International2016, 106-113
  • Industrial Crops and Products2022, 188:115638
  • Vietnam Journal of Food Control2022, 5(3):pp.390-401.
  • Planta Med.2019, 85(3):217-224
  • Metabolites2023, 13(1), 3.
  • Antioxidants (Basel).2021, 10(1):112.
  • Int J Oncol.2016, 49(4):1497-504
  • Toxicol Res.2019, 35(4):371-387
  • Int J Biol Macromol.2019, 126:653-661
  • Appl. Sci. 2021, 11(17),7829
  • J Nat Prod.2019, 82(4):1002-1008
  • Molecules.2021, 26(9):2791.
  • Food Chem.2021, 360:130063.
  • Phytomedicine.2019, 57:95-104
  • Applied Biological Chemistry2022, 65(85).
  • Molecules.2020, 25(17):3783.
  • Plants (Basel).2020, 9(11):1422.
  • ...
  • 生物活性
    Description: Kanshone A shows cytotoxic activity against P-388 cells.
    In vitro:
    Zhong Yao Cai. 2007 Jan;30(1):38-41.
    Study on the active components of Nardostachys chinensis.[Pubmed: 17539300]

    METHODS AND RESULTS:
    To study on the active components of Nardostachys chinensis Batal, the compounds were isolated and purified by chromatographic methods, with their structures identified by spectral analysis and comparison with published data. 9 compounds were obtained and their structures were identified as acaciin, ursolie acid, octacosanol, kanshone A, nardosinonediol, nardosinone, aristolen-9beta-ol, oleanolic acid and beta-sitosterol. Acaciin, ursolie acid and octacosanol were obtained from Nardostachys chinensis Batal. for the first time.
    CONCLUSIONS:
    Acaciin and ursolie are the active components of antihiotics and anti-inflammatory.
    Chem Pharm Bull (Tokyo). 1993 Jun;41(6):1183-4.
    Cytotoxic sesquiterpenes from Nardostachys chinensis.[Pubmed: 8370115]

    METHODS AND RESULTS:
    Five cytostatic sesquiterpenes, desoxo-narchinol-A (1), nardosinone (2), debilon (3), nardosinonediol (4) and Kanshone A (5), were isolated from the roots and rhizomes of Nardostachys chinensis (Valerianaceae). The steric structure of 1 was determined by nuclear Overhauser effects (NOEs) and the exciton chirality method.
    CONCLUSIONS:
    All five showed cytotoxic activity against P-388 cells and the structure-activity relationship of 1 was also discussed.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 4.2675 mL 21.3374 mL 42.6749 mL 85.3497 mL 106.6872 mL
    5 mM 0.8535 mL 4.2675 mL 8.535 mL 17.0699 mL 21.3374 mL
    10 mM 0.4267 mL 2.1337 mL 4.2675 mL 8.535 mL 10.6687 mL
    50 mM 0.0853 mL 0.4267 mL 0.8535 mL 1.707 mL 2.1337 mL
    100 mM 0.0427 mL 0.2134 mL 0.4267 mL 0.8535 mL 1.0669 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    Debilon; Debilon CFN89419 26808-51-5 C15H22O2 = 234.33 5 mg QQ客服:1457312923
    Nardoaristolone B; Nardoaristolone B CFN95203 1422517-82-5 C14H18O2 = 218.3 5mg QQ客服:1413575084
    甘松香酮 A; Kanshone A CFN96977 115356-18-8 C15H22O2 = 234.33 5mg QQ客服:3257982914
    甘松新酮二醇; Nardosinonediol CFN89546 20489-11-6 C15H24O3 = 252.34 5mg QQ客服:2056216494
    异甘松新酮; Isonardosinone CFN95180 27062-01-7 C15H20O4 = 264.3 10mg QQ客服:2056216494
    Narchinol B; Narchinol B CFN89522 1356822-09-7 C12H16O3 = 208.25 5mg QQ客服:2159513211
    Desoxo-narchinol A; Desoxo-narchinol A CFN89358 53859-06-6 C12H16O2 = 192.25 5mg QQ客服:1413575084
    努特卡酮, 诺卡酮; Nootkatone CFN98699 4674-50-4 C15H22O = 218.3 20mg QQ客服:2056216494
    Oxyphyllol B; Oxyphyllol B CFN95575 226546-99-2 C15H22O2 = 234.3 5mg QQ客服:3257982914
    Tessaric acid; Tessaric acid CFN95182 58142-10-2 C15H20O3 = 248.3 5mg QQ客服:215959384

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