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  • 焦地黄苯乙醇甙A1

    Jionoside A1

    焦地黄苯乙醇甙A1
    产品编号 CFN90809
    CAS编号 120444-60-2
    分子式 = 分子量 C36H48O20 = 800.8
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Polyphenols
    植物来源 The roots of Rehmannia glutinosa
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    焦地黄苯乙醇甙A1 CFN90809 120444-60-2 1mg QQ客服:215959384
    焦地黄苯乙醇甙A1 CFN90809 120444-60-2 5mg QQ客服:215959384
    焦地黄苯乙醇甙A1 CFN90809 120444-60-2 10mg QQ客服:215959384
    焦地黄苯乙醇甙A1 CFN90809 120444-60-2 20mg QQ客服:215959384
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • Siksha O Anusandhan University (India)
  • University of British Columbia (Canada)
  • University of Liège (Belgium)
  • Sant Gadge Baba Amravati University (India)
  • Northeast Normal University Changchun (China)
  • Harvard University (USA)
  • Universidade Federal de Pernambuco (UFPE) (Brazil)
  • University of Fribourg (Switzerland)
  • Nicolaus Copernicus Uniwersity (Poland)
  • Auburn University (USA)
  • Semmelweis Unicersity (Hungary)
  • Institute of Tropical Disease Universitas Airlangga (Indonesia)
  • Fraunhofer-Institut für Molekularbiologie und Angewandte ?kologie IME (Germany)
  • Instituto Politécnico de Bragan?a (Portugal)
  • More...
  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Front. Pharmacol.2022, 901563.
  • Molecules.2022, 27(19):6651.
  • Food and Fermentation Industries2019, 45(7):45-51
  • Food Sci Nutr.2023, 11(9):5532-5542.
  • Kangwon National University2022, 37(1):29-37
  • J Appl Biol Chem2022, 65:343−348.
  • GENENCELL2023, 25:4356740
  • Evid Based Complement Alternat Med.2018, 2018:4580627
  • Asian Pac J Cancer Prev.2021, 22(S1):97-106.
  • Indian J. of Experimental Bio.2020, 9(58).
  • Biomed Pharmacother.2023, 166:115329.
  • Biochem Biophys Res Commun.2018, 505(1):261-266
  • Jour. of Stored Pro & Postharvest Res.2016, 7(3):32-36
  • Russian J Bioorganic Chemistry 2021, 47:1411-1417.
  • Korean Journal of Pharmacognosy2018, 49(3):270-277
  • Int J Mol Med.2019, 43(6):2516-2522
  • Free Radic Biol Med.2016, 97:307-319
  • J Sci Food Agric.2018, 98(3):1153-1161
  • Pathogens.2018, 7(3):E62
  • J Chromatogr B Analyt Technol Biomed Life Sci. 2017, 1064:115-123
  • Front Pharmacol.2021, 12:762829.
  • PLoS One.2018, 13(4):e0195642
  • Chemistry of Vegetable Raw Materials2019, 3:119-127
  • ...
  • 生物活性
    Description: Jionoside A1 displays dose dependent immune-enhancement activity and possesses moderate neuroprotective activities on H2O2-treated SH-SY5Y cells.
    Targets: Immunology & Inflammation related
    In vitro:
    J. Pharm. Biomed. Anal., 2015, 117(6):363-71.
    Identification of bioactive ingredients with immuno-enhancement and anti-oxidative effects from Fufang-Ejiao-Syrup by LC-MS(n) combined with bioassays.[Pubmed: 26433168 ]
    Fufang Ejiao Syrup (FES) is a widely used immune-boosting Traditional Chinese Medicine (TCM) in Eastern Asian countries. This study attempts to investigate the bioactive compounds in FES.
    METHODS AND RESULTS:
    First, FES extract was separated into fractions to facilitate the investigation and 72 compounds were identified using LC-MS(n). Subsequently, Immune-enhancement effects of FES and its components were investigated on bone marrow cells and neuroprotective effects against H2O2 induced oxidative damage were evaluated in SH-SY5Y neuroblastoma cells and bEnd.3. Our results indicated that fraction 3, 5, 6 and 8 showed significant improvements on immune function, while several fractions had cytoprotective effects against H2O2-induced oxidative injury. Jionoside A1 isolated from Radix Rehmanniae Praeparata displayed dose dependent immune-enhancement activity. 20(R)-ginsenoside Rg3 could protect bEnd.3 against oxidative damage. Furthermore, echinacoside, jionoside A1, vitexin-2-O-rhamnoside, acteoside and isoacteoside possessed moderate protective activities on H2O2-treated SH-SY5Y cells.
    CONCLUSIONS:
    In conclusion, our study provided both chemical and biological evidences to support clinical application of FES.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 1.2488 mL 6.2438 mL 12.4875 mL 24.975 mL 31.2188 mL
    5 mM 0.2498 mL 1.2488 mL 2.4975 mL 4.995 mL 6.2438 mL
    10 mM 0.1249 mL 0.6244 mL 1.2488 mL 2.4975 mL 3.1219 mL
    50 mM 0.025 mL 0.1249 mL 0.2498 mL 0.4995 mL 0.6244 mL
    100 mM 0.0125 mL 0.0624 mL 0.1249 mL 0.2498 mL 0.3122 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    管花苷B; Tubuloside B CFN91712 112516-04-8 C31H38O16 = 666.6 10mg QQ客服:2056216494
    管花肉苁蓉苷C1; Cistantubuloside C1 CFN95121 620632-36-2 C35H46O21 = 802.7 10mg QQ客服:2159513211
    肉苁蓉苷A; Cistanoside A CFN90526 93236-42-1 C36H48O20 = 800.75 20mg QQ客服:1457312923
    安格洛苷C; 安格洛甙C; Angoroside C CFN98149 115909-22-3 C36H48O19 = 784.75 20mg QQ客服:215959384
    Teupolioside; Teupolioside CFN70272 143617-02-1 C35H46O20 = 786.7 5mg QQ客服:1413575084
    2-肉桂酰葡萄糖苷; 2-O-cinnamoyl-beta-D-glucose CFN95111 N/A C15H18O7 = 310.3 5mg QQ客服:2056216494
    6-O-(E)-咖啡酰基葡萄糖苷; 6-O-(E)-Caffeoylglucopyranose CFN95105 209797-79-5 C15H18O9 = 342.3 5mg QQ客服:215959384
    6-O-阿魏酰葡萄糖; 6-O-Feruloylglucose CFN99431 137887-25-3 C16H20O9 = 356.3 5mg QQ客服:215959384
    6'-O-阿魏酰蔗糖; Arillatose B CFN99432 137941-45-8 C22H30O14 = 518.5 5mg QQ客服:1413575084
    1-O-阿魏酰葡萄糖; 1-O-Feruloylglucose CFN95596 64625-37-2 C16H20O9 = 356.3 5mg QQ客服:1457312923

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