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  • 异石当归素

    Isosaxalin

    异石当归素
    产品编号 CFN98929
    CAS编号 55481-86-2
    分子式 = 分子量 C16H15ClO5 = 322.7
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Coumarins
    植物来源 The roots of Angelica polymorpha Maxim.
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    异石当归素 CFN98929 55481-86-2 1mg QQ客服:2056216494
    异石当归素 CFN98929 55481-86-2 5mg QQ客服:2056216494
    异石当归素 CFN98929 55481-86-2 10mg QQ客服:2056216494
    异石当归素 CFN98929 55481-86-2 20mg QQ客服:2056216494
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    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
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    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
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    IF=12.804(2019)

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  • University of Eastern Finland (Finland)
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  • 国外学术期刊发表的引用ChemFaces产品的部分文献
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  • Eur J Neurosci.2021, 53(11):3548-3560.
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  • Molecules.2020, 25(7):1625.
  • J. Soc. Cosmet. Sci. Korea2021, 47(1):57-63
  • Applied Biological Chemistry2022, 65(77).
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  • Journal of Functional Foods2022, 98:105271.
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  • ...
  • 生物活性
    Description: Isosaxalin, heraclenin and heraclenol 3'-Me ether have melanin biosynthesis inhibitory activities.
    In vitro:
    Korean Journal of Microbiology & Biotechnology, 2003 , 47 (12) :3829-36.
    Melanin biosynthesis inhibitory activities of coumarins isolated from Angelica polymorpha MAXIM[Reference: WebLink]

    METHODS AND RESULTS:
    During the screening for inhibitors of melanin biosynthesis from plant extract, Angelica polymorpha MAXIM which showed a high lecel of inhibition was selected. The inhibiting substances were purified form methanol extract of Angelica Polymorpha MAXIM followed by silica gel column chromatography and HPLC. The inhibitors were identified as heraclenin, Isosaxalin and heraclenol 3'-Me ether , by spectroscopic methods of ESI-MS, ©öH-NMR,©ö©øC-NMR, DEPT, HMQC and HMBC.
    CONCLUSIONS:
    These compounds did not have mushroom tyrosinase inhibitory activity, but showed a highly potent melanin biosynthesis inhibition zone in the plate culture of Streptomyces bikiniensis, a bacterium used as an indicator organism in this work. These compounds did not show any growth inhibition against S. bikiniensis at the same concentration of melanin biosynthesis test
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 3.0989 mL 15.4943 mL 30.9885 mL 61.9771 mL 77.4713 mL
    5 mM 0.6198 mL 3.0989 mL 6.1977 mL 12.3954 mL 15.4943 mL
    10 mM 0.3099 mL 1.5494 mL 3.0989 mL 6.1977 mL 7.7471 mL
    50 mM 0.062 mL 0.3099 mL 0.6198 mL 1.2395 mL 1.5494 mL
    100 mM 0.031 mL 0.1549 mL 0.3099 mL 0.6198 mL 0.7747 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    欧前胡素; Imperatorin CFN98758 482-44-0 C16H14O4 = 270.3 20mg QQ客服:1413575084
    独活素; Heraclenin CFN98354 2880-49-1 C16H14O5 = 286.3 5mg QQ客服:215959384
    异栓翅芹醇; Isogosferol CFN98890 53319-52-1 C16H14O5 = 286.3 5mg QQ客服:3257982914
    异石当归素; Isosaxalin CFN98929 55481-86-2 C16H15ClO5 = 322.7 5mg QQ客服:2056216494
    白芷属脑; Heraclenol CFN98402 31575-93-6 C16H16O6 = 304.3 10mg QQ客服:1413575084
    (-)-白藏属脑; (-)-Heraclenol CFN89405 139079-42-8 C16H16O6 = 304.29 5mg QQ客服:2159513211
    独活属醇缩丙酮; Heraclenol acetonide CFN97112 64790-68-7 C19H20O6 = 344.4 5mg QQ客服:215959384
    3'-O-BETA-D-吡喃葡萄糖苷白芷属脑酯; Heraclenol 3'-O-beta-D-glucopyranoside CFN98410 32207-10-6 C22H26O11 = 466.4 5mg QQ客服:2056216494
    Heraclenol 3'-O-[beta-D-apiofuranosyl-(1-6)-beta-D-glucopyranoside]; Heraclenol 3'-O-[beta-D-apiofuranosyl-(1-6)-beta-D-glucopyranoside] CFN97243 765316-44-7 C27H34O15 = 598.6 5mg QQ客服:1457312923
    Rivulobirin E; Rivulobirin E CFN98247 237407-59-9 C32H30O11 = 590.6 5mg QQ客服:2056216494

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