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  • 山香二烯酸

    Hyptadienic acid

    山香二烯酸
    产品编号 CFN99387
    CAS编号 128397-09-1
    分子式 = 分子量 C30H46O4 = 470.7
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Triterpenoids
    植物来源 The leaf of Eriobotrya japonica
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    山香二烯酸 CFN99387 128397-09-1 1mg QQ客服:1457312923
    山香二烯酸 CFN99387 128397-09-1 5mg QQ客服:1457312923
    山香二烯酸 CFN99387 128397-09-1 10mg QQ客服:1457312923
    山香二烯酸 CFN99387 128397-09-1 20mg QQ客服:1457312923
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • Kitasato University (Japan)
  • Charles University in Prague (Czech Republic)
  • University of Stirling (United Kingdom)
  • University of Auckland (New Zealand)
  • University of Mysore (India)
  • Srinakharinwirot University (Thailand)
  • Tokyo Woman's Christian University (Japan)
  • University of Minnesota (USA)
  • Northeast Normal University Changchun (China)
  • University Medical Center Mainz (Germany)
  • Semmelweis Unicersity (Hungary)
  • Harvard University (USA)
  • Instituto Politécnico de Bragan?a (Portugal)
  • Gyeongsang National University (Korea)
  • More...
  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Front Pharmacol.2018, 9:236
  • Key Engineering Materials2022, 931(47-53).
  • Sci Rep.2020, 10:4495(2020)
  • J Ethnopharmacol.2019, 236:31-41
  • Drug Des Devel Ther.2020, 14:5189-5204.
  • J Microbiol Biotechnol.2022, 32(2):141-148.
  • Sci Rep.2019, 9(1):18080
  • Sci Rep.2016, 6:25094
  • Appl. Sci.2020, 10(5),1713.
  • J Appl Biol Chem2023, 66:455−461
  • Cell Death Dis.2019, 10(12):882
  • Front Pharmacol.2022, 13:972825.
  • Nanjing University of Chinese Medicine2022, 345930.
  • Research Square2021, March 3rd.
  • Food and Agriculture Org. Of the UN2019, 151-160
  • Sci Rep.2019, 9(1):4646
  • J Ethnopharmacol.2020, 254:112733.
  • LWT2021, 147:111620.
  • Molecules.2020, 25(23):5556.
  • Drug Des Devel Ther.2020, 14:61-71
  • PLoS One.2022, 17(4):e0267007.
  • Pest Manag Sci.2023, 79(8):2675-2685.
  • Int. J. Mol. Sci.2022, 23(19), 11900.
  • ...
  • 生物活性
    Description: Hyptadienic acid exhibits moderate cytotoxicity against HepG2 cells.It also shows a marked anti-inflammatory effect, it also exhibits strong antitumor-promoting activity in an in vivo two-stage carcinogenesis test of mouse tumor by using 7,12-dimethylbenz(a)anthracene (DMBA) as an initiator and TPA as a promoter.
    Targets: Immunology & Inflammation related
    In vitro:
    Pharm. Biol., 2003, 41(5):375-8.
    Constituents of Salvia trijuga.[Reference: WebLink]

    METHODS AND RESULTS:
    A new oleanane-type glycoside, trijugaoside A, together with thirty known compounds, was isolated from the whole plant of Salvia trijuga (Lamiaceae). The structure of the new compound was elucidated on the basis of spectral and chemical evidence.
    CONCLUSIONS:
    Hyptadienic acid isolated from the plant extract exhibited moderate cytotoxicity against HepG2 cells.
    In vivo:
    Biosci Biotechnol Biochem. 2004 Jan;68(1):85-90.
    Triterpene acids from the leaves of Perilla frutescens and their anti-inflammatory and antitumor-promoting effects.[Pubmed: 14745168]

    METHODS AND RESULTS:
    Nine triterpene acids, viz., six of the ursane type, ursolic acid (1), corosolic acid (2), 3-epicorosolic acid (3), pomolic acid (4), tormentic acid (5) and hyptadienic acid (6), and three of the oleanane type, oleanolic acid (7), augustic acid (8) and 3-epimaslinic acid (9), among which 1 constituted the most predominant triterpene acid, were isolated and identified from ethanol extracts of the leaves of red perilla [Perilla frutescens (L.) Britton var. acuta Kudo] and green perilla [P. frutescens (L.) Britton var. acuta Kudo forma viridis Makino]. These eight compounds, 1, 2, 4-9, were evaluated for their inhibitory effects on 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced inflammation (1 microg/ear) in mice.
    CONCLUSIONS:
    All the compounds tested showed a marked anti-inflammatory effect, with a 50% inhibitory dose (ID50) of 0.09-0.3 mg per ear. In addition, an evaluation against the Epstein-Barr virus early antigen (EBV-EA) activation induced by TPA showed five compounds, 1-3, 5 and 9, with a potent inhibitory effect on EBV-EA induction (91-93% inhibition at 1x10(3) mol ratio/TPA). Furthermore, compound 5 exhibited strong antitumor-promoting activity in an in vivo two-stage carcinogenesis test of mouse tumor by using 7,12-dimethylbenz(a)anthracene (DMBA) as an initiator and TPA as a promoter.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 2.1245 mL 10.6225 mL 21.245 mL 42.4899 mL 53.1124 mL
    5 mM 0.4249 mL 2.1245 mL 4.249 mL 8.498 mL 10.6225 mL
    10 mM 0.2124 mL 1.0622 mL 2.1245 mL 4.249 mL 5.3112 mL
    50 mM 0.0425 mL 0.2124 mL 0.4249 mL 0.8498 mL 1.0622 mL
    100 mM 0.0212 mL 0.1062 mL 0.2124 mL 0.4249 mL 0.5311 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    山香二烯酸; Hyptadienic acid CFN99387 128397-09-1 C30H46O4 = 470.7 5mg QQ客服:2056216494
    Rosamultic acid; Rosamultic acid CFN92608 214285-76-4 C30H46O5 = 486.7 5mg QQ客服:2056216494

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