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  • 小连翘次碱,角茴香酮碱

    Hypecorinine

    小连翘次碱,角茴香酮碱
    产品编号 CFN92333
    CAS编号 41787-57-9
    分子式 = 分子量 C20H17NO6 = 367.4
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Alkaloids
    植物来源 The herbs of Hypecoum erectum L.
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    小连翘次碱,角茴香酮碱 CFN92333 41787-57-9 1mg QQ客服:1457312923
    小连翘次碱,角茴香酮碱 CFN92333 41787-57-9 5mg QQ客服:1457312923
    小连翘次碱,角茴香酮碱 CFN92333 41787-57-9 10mg QQ客服:1457312923
    小连翘次碱,角茴香酮碱 CFN92333 41787-57-9 20mg QQ客服:1457312923
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • Institute of Chinese Materia Medica (China)
  • The Ohio State University (USA)
  • Stanford University (USA)
  • Aveiro University (Portugal)
  • Max-Planck-Insitut (Germany)
  • University of Bordeaux (France)
  • University of Hawaii Cancer Center (USA)
  • Imperial College London (United Kingdom)
  • University of Maryland (USA)
  • National Chung Hsing University (Taiwan)
  • Cornell University (USA)
  • Universidad de Buenos Aires (Argentina)
  • Institute of Bioorganic Chemistry Polish Academy of Sciences (Poland)
  • University of Padjajaran (Indonesia)
  • More...
  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Chinese Medicine2019, 14(1)
  • Indian J Pharm Sci.2022, 84(3):144-151
  • Plos One.2020, 10.1371
  • J Cell Physiol.2021, 236(3):1950-1966.
  • Neurotox Res.2020, 38(1):163-174.
  • Primary and Industrial.2018, 52(11)
  • Plants (Basel).2022, 11(21):2947.
  • Agriculture2022, 12(12), 2173.
  • Front Pharmacol.2021, 12:770667.
  • Phytother Res.2022, 10.1002:ptr.7592.
  • Toxins (Basel).2019, 11(10):E575
  • Int J Mol Sci.2022, 23(21):12816.
  • Phytomedicine.2019, 58:152893
  • LWT - Food Science and Technology2022, 164:113627
  • PLoS One.2018, 13(4):e0195642
  • Phytother Res.2019, 33(7):1784-1793
  • Asian J of Pharmaceutical&Clinical 2018, 11(2)
  • University of Guelph2021, 12.
  • BMC Complement Altern Med.2017, 17(1):384
  • Molecules.2019, 24(6):E1177
  • Daru.2022, 30(2):273-288.
  • Molecules.2023, 28(19):6775.
  • J Ethnopharmacol.2016, 192:370-381
  • ...
  • 生物活性
    Description: Hypecorinine shows promising antibacterial activity.
    Targets: Antifection
    In vitro:
    Journal of Medicinal Plants Research, 2011 , 5 (22) :5428-32.
    Seven alkaloids and their antibacterial activity from Hypecoum erectum L[Reference: WebLink]

    METHODS AND RESULTS:
    From the aerial part of Hypecoum erectum L., seven alkaloids, Protopine (1), Cryptopine (2), Allocryptopine (3), Hypecorinine (4), (-)-N-Methylcanadine (5), Oxohydrastinine (6) and N-Methylcorydaldine (7) were isolated. The structures of the seven compounds were established by 1 H-NMR, 13 C-NMR, DEPT and ESI-MS analyses. Compounds 2, 5 and 7 were obtained from this plant for the first time. The antibacterial activities were investigated against six bacteria (3 gram-positive and 3 gram-negative) by disc diffusion method followed by the minimal inhibitory concentration (MIC) which was determined using a two fold serial dilution assay for the compound which have inhibitory effect.
    CONCLUSIONS:
    In vitro antimicrobial activities assay indicated that some compounds showed promising activities. To the best of our knowledge, this is the first report on the antimicrobial properties of these alkaloids from this plant.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 2.7218 mL 13.6091 mL 27.2183 mL 54.4366 mL 68.0457 mL
    5 mM 0.5444 mL 2.7218 mL 5.4437 mL 10.8873 mL 13.6091 mL
    10 mM 0.2722 mL 1.3609 mL 2.7218 mL 5.4437 mL 6.8046 mL
    50 mM 0.0544 mL 0.2722 mL 0.5444 mL 1.0887 mL 1.3609 mL
    100 mM 0.0272 mL 0.1361 mL 0.2722 mL 0.5444 mL 0.6805 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    (-)-紫堇明; (-)-Corlumine CFN96340 79082-64-7 C21H21NO6 = 383.4 5mg QQ客服:1413575084
    (+)-荷包牡丹碱; 右旋荷包牡丹碱; 毕枯枯林; 山乌龟碱; (+)-Bicuculline CFN99748 485-49-4 C20H17NO6 = 367.36 20mg QQ客服:1457312923
    (-)-荷包牡丹碱甲氯化物; (-)-Bicuculline methochloride CFN92860 53552-05-9 C21H20NO6.Cl = 417.8 5mg QQ客服:1457312923
    小连翘次碱,角茴香酮碱; Hypecorinine CFN92333 41787-57-9 C20H17NO6 = 367.4 5mg QQ客服:1457312923
    异直立角茴香碱; Isohyperectine CFN92448 170384-75-5 C24H21N3O6 = 447.5 5mg QQ客服:215959384
    直立角茴香碱; Hyperectine CFN92449 94656-46-9 C24H21N3O6 = 447.5 5mg QQ客服:2159513211
    原水仙碱; Colchiceine CFN91828 477-27-0 C21H23NO6 = 385.4 5mg QQ客服:1413575084
    秋水仙碱; Colchicine CFN99514 64-86-8 C22H25NO6 = 399.44 20mg QQ客服:2056216494
    N-甲基-秋水仙碱; N-Methylcolchicine CFN91817 7336-40-5 C23H27NO6 = 413.5 5mg QQ客服:215959384
    硫代秋水仙碱; Thiocolchicine CFN91554 2730-71-4 C22H25NO5S = 415.5 5mg QQ客服:1413575084

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