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  • 高车前素 7-O-新橙皮糖苷

    Hispidulin 7-O-neohesperidoside

    高车前素 7-O-新橙皮糖苷
    产品编号 CFN90892
    CAS编号 156186-00-4
    分子式 = 分子量 C28H32O15 = 608.6
    产品纯度 >=98%
    物理属性 Yellow powder
    化合物类型 Flavonoids
    植物来源 The herbs of Plantago asiatica L.
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    高车前素 7-O-新橙皮糖苷 CFN90892 156186-00-4 1mg QQ客服:1457312923
    高车前素 7-O-新橙皮糖苷 CFN90892 156186-00-4 5mg QQ客服:1457312923
    高车前素 7-O-新橙皮糖苷 CFN90892 156186-00-4 10mg QQ客服:1457312923
    高车前素 7-O-新橙皮糖苷 CFN90892 156186-00-4 20mg QQ客服:1457312923
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • The Ohio State University (USA)
  • John Innes Centre (United Kingdom)
  • Medical University of South Carolina (USA)
  • Florida A&M University (USA)
  • National Research Council of Canada (Canada)
  • Sri Sai Aditya Institute of Pharmaceutical Sciences and Research (India)
  • Korea Intitute of Science and Technology (KIST) (Korea)
  • University of British Columbia (Canada)
  • Gyeongsang National University (Korea)
  • Instytut Nawozów Sztucznych w Pu?awach (Poland)
  • University of Malaya (Malaysia)
  • University of Queensland (Australia)
  • University of Leipzig (Germany)
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  • More...
  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Plant Direct.2021, 5(12):e372.
  • Journal of functional foods2018, 171-182
  • Chem Res Toxicol.2023, 36(2):213-229.
  • Cardiovasc Toxicol.2019, 19(4):297-305
  • Cancers (Basel).2021, 13(9):2223.
  • Plant Physiol Biochem.2021, 160:166-174.
  • Biochem Biophys Res Commun.2018, 505(4):1148-1153
  • Int J Mol Sci.2022, 23(23):14545.
  • SBRAS2016, 12
  • Chinese Journal of Hospital Pharmacy2020, 40(7)
  • Agriculture.2022, 12(3), 342.
  • Chemistry of Vegetable Raw Materials2019, 3:119-127
  • Ind Crops Prod.2015, 67:185-191
  • CZECH MYCOLOGY2021, 73(1):1-19.
  • Cardiovasc Toxicol.2021, 21(11):947-963.
  • Toxicol In Vitro.2023, 86:105521.
  • Biochem Biophys Res Commun.2021, 534:802-807.
  • Food Res Int.2020, 133:109130.
  • J Pharmaceutical and Biomedical Analysis2022, 114631.
  • J Applied Biological Chemistry2021, 64(2):185-192
  • Nutrients.2021, 13(1):254.
  • Srinagarind Medical Journal2017, 32(1)
  • Molecules.2022, 27(7):2360.
  • ...
  • 生物活性
    Description: Hispidulin 7-O-neohesperidoside is one of the active substances responsible for the protective effects of this plant.
    In vivo:
    Phytother Res. 2004 Jan;18(1):19-24.
    Effects of methanol extract of Cirsium japonicum var. ussuriense and its principle, hispidulin-7-O-neohesperidoside on hepatic alcohol-metabolizing enzymes and lipid peroxidation in ethanol-treated rats.[Pubmed: 14750195]
    Effects of the methanol extract of Cirsium japonicum var. ussuriense and Hispidulin 7-O-neohesperidoside isolated from the plant on hepatic alcohol-metabolizing enzymes and lipid peroxidation were studied in rats treated with ethanol.
    METHODS AND RESULTS:
    Rats treated with 10% alcohol solution for 6 weeks were orally administered with 250 or 500 mg of methanol extract or 10 or 20 mg of Hispidulin 7-O-neohesperidoside per kg body weight daily during the last week of ethanol treatment. The administration of the methanol extract of herbal plant and Hispidulin 7-O-neohesperidoside in ethanol-treated rats significantly enhanced the activities of hepatic alcohol dehydrogenase, microsomal ethanol-oxidizing system and aldehyde dehydrogenase in a dose-dependent manner. The extract and the compound decreased hepatic lipid peroxidation along with an increase in hepatic content of reduced glutathione. The methanol extract and Hispidulin 7-O-neohesperidoside of C. japonicum var. ussuriense also increased the activity of glutathione reductase, but had no effect on gamma-glutamylcysteine synthase.
    CONCLUSIONS:
    The results suggest that C. japonicum var. ussuriense may alleviate alcoholic toxicity by enhancing ethanol oxidation as well as inhibiting lipid peroxidation, and Hispidulin 7-O-neohesperidoside is one of the active substances responsible for the protective effects of this plant.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 1.6431 mL 8.2156 mL 16.4312 mL 32.8623 mL 41.0779 mL
    5 mM 0.3286 mL 1.6431 mL 3.2862 mL 6.5725 mL 8.2156 mL
    10 mM 0.1643 mL 0.8216 mL 1.6431 mL 3.2862 mL 4.1078 mL
    50 mM 0.0329 mL 0.1643 mL 0.3286 mL 0.6572 mL 0.8216 mL
    100 mM 0.0164 mL 0.0822 mL 0.1643 mL 0.3286 mL 0.4108 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    Comanthosid A; Comanthosid A CFN91173 70938-59-9 C24H24O12 = 504.5 5mg QQ客服:1457312923
    高车前素-4'-O-β-D-葡萄糖苷; Hispidulin 4'-O-beta-D-glucopyranoside CFN91833 244285-12-9 C22H22O11 = 462.4 5mg QQ客服:2159513211
    滨蓟黄甙; Cirsimarin CFN96507 13020-19-4 C23H24O11 = 476.43 5mg QQ客服:3257982914
    5,8,4'-三羟基-7-甲氧基黄酮8-O-葡萄糖甙; 5,8,4'-Trihydroxy-7-methoxyflavone 8-O-glucoside CFN97699 710952-13-9 C22H22O11 = 462.41 5mg QQ客服:1413575084
    田蓟苷; Tilianin CFN92764 4291-60-5 C22H22O10 = 446.1 20mg QQ客服:2159513211
    蒙花苷; Linarin CFN98738 480-36-4 C28H32O14 = 592.6 20mg QQ客服:2159513211
    金柑苷; Fortunellin CFN70305 20633-93-6 C28H32O14 = 592.6 10mg QQ客服:1413575084
    金合欢素 7-[鼠李糖-(1->2)-半乳糖醛酸苷]; Acacetin 7-[rhamnosyl-(1->2)-galacturonide] CFN95358 38722-95-1 C28H30O15 = 606.5 10mg QQ客服:1413575084
    密蒙花新甙; Neobudofficide CFN95640 194602-91-0 C34H42O18 = 738.7 10mg QQ客服:215959384
    金柑苷-6''-beta-D-葡萄糖苷; Fortunellin-6''-beta-D-glucopyranoside (Acacetin-7-O-[2''-O-rhamnosyl-6''-O-glucosyl]-glucoside) CFN95315 1218774-64-1 C34H42O19 = 754.7 5mg QQ客服:1413575084

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