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  • 天芥菜碱 N-氧化物

    Heliotrine N-oxide

    天芥菜碱 N-氧化物
    产品编号 CFN00271
    CAS编号 6209-65-0
    分子式 = 分子量 C16H27NO6 = 329.39
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Alkaloids
    植物来源 The herbs of Cynoglossum amabile
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    天芥菜碱 N-氧化物 CFN00271 6209-65-0 1mg QQ客服:2159513211
    天芥菜碱 N-氧化物 CFN00271 6209-65-0 5mg QQ客服:2159513211
    天芥菜碱 N-氧化物 CFN00271 6209-65-0 10mg QQ客服:2159513211
    天芥菜碱 N-氧化物 CFN00271 6209-65-0 20mg QQ客服:2159513211
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
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  • National Hellenic Research Foundation (Greece)
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  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Heliyon2022, 8(2):e08866.
  • Pharmacognosy Magazine2018, 14(56):418-424
  • Molecules.2021, 26(2):313.
  • Reprod Toxicol.2020, 96:1-10.
  • Food Control2022, 132:108434.
  • Phytomedicine2022, 104:154337.
  • Molecules.2022, 27(4):1412.
  • South African Journal of Botany2021, 142:114-123.
  • Biomedicines.2022, 10(3):583.
  • Separations2023, 10(11), 567;
  • Biomedicines.2020, 8(11):486.
  • BMC Complement Altern Med.2018, 18(1):221
  • Int J Oncol.2016, 49(4):1497-504
  • J Int Med Res.2021, 49(7):3000605211032849.
  • Mie University2019, 10076.
  • Food Funct.2020, 11(2):1322-1333.
  • Mol Cells.2018, 41(8):771-780
  • Antioxidants (Basel).2020, 9(6):466.
  • Evid Based Complement Alternat Med.2016, 2016:1739760
  • TCI CO.2019, US20190151257A1
  • Phytomedicine.2019, 57:95-104
  • Rev. Chim.2020, 71(3),558-564
  • Curr Eye Res.2018, 43(1):27-34
  • ...
  • 生物活性
    Description: Heliotrine N-oxide was used as an internal standard.
    In vivo:
    Biomed Mass Spectrom. 1980 Feb;7(2):65-73.
    Direct quantitative analysis of indicine-N-oxide in cancer patient samples by gas chromatography using the internal standard heliotrine-N-oxide including a mass spectral comparison of their trimethylsilyl derivatives.[Pubmed: 7407334 ]

    METHODS AND RESULTS:
    Indicine-N-oxide was analyzed quantitatively in biological samples using a direct partial purification method involving acetonitrite precipitation or methanol precipitation followed by ion exchange chromatography. Trimethylsilyl derivatization of the resultant provided either of two derivatives, depending on the reaction conditions used, both of which had good gas chromatographic qualities. Heliotrine N-oxide was used as the internal standard for this work. Data are presented to show that this is a reliable and useful internal standard based on its behavior in the partial purification method and on the gas chromatographic characteristics of its two derivatives. In addition, both low and high resolution mass spectral data indicate that heliotrine N-oxide produces two trimethylsilyl derivatives analogous to those produced by indicine N-oxide under the same conditions.
    CONCLUSIONS:
    Application of this procedure to urine and blood samples from cancer patients in clinical trials indicates that over 95% of the drug is removed from the circulation and excreted in the urine over the course of 48 h.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 3.0359 mL 15.1796 mL 30.3591 mL 60.7183 mL 75.8979 mL
    5 mM 0.6072 mL 3.0359 mL 6.0718 mL 12.1437 mL 15.1796 mL
    10 mM 0.3036 mL 1.518 mL 3.0359 mL 6.0718 mL 7.5898 mL
    50 mM 0.0607 mL 0.3036 mL 0.6072 mL 1.2144 mL 1.518 mL
    100 mM 0.0304 mL 0.1518 mL 0.3036 mL 0.6072 mL 0.759 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    阔叶碱; Latifoline CFN00266 6029-86-3 C20H27NO7 = 393.44 5mg QQ客服:1413575084
    阔叶碱N-氧化物; Latifoline N-oxide CFN00267 98752-06-8 C20H27NO8 = 409.43 5mg QQ客服:215959384
    天芥菜品碱; Heliosupine CFN00268 32728-78-2 C20H31NO7 = 397.47 5mg QQ客服:3257982914
    天芥菜品碱N-氧化物; Heliosupine N-oxide CFN00454 31701-88-9 C20H31NO8 = 413.5 5mg QQ客服:1457312923
    乙酰天芥菜品碱; Acetylheliosupine CFN00269 31514-30-4 C22H33NO8 = 439.50 5mg QQ客服:1457312923
    天芥菜碱; Heliotrine CFN00270 303-33-3 C16H27NO5 = 313.39 5mg QQ客服:1457312923
    天芥菜碱 N-氧化物; Heliotrine N-oxide CFN00271 6209-65-0 C16H27NO6 = 329.39 5mg QQ客服:2159513211
    大叶千里光碱; Macrophylline CFN00275 27841-97-0 C13H21NO3 = 239.31 5mg QQ客服:2056216494
    欧天芥菜碱; Europine CFN00264 570-19-4 C16H27NO6 = 329.39 5mg QQ客服:1413575084
    欧天芥菜碱氮氧化物; Europine N-oxide CFN00265 65582-53-8 C16H27NO7 = 345.39 5mg QQ客服:1457312923

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