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  • GB 1a

    GB 1a

    GB 1a
    产品编号 CFN96934
    CAS编号 220611-41-6
    分子式 = 分子量 C30H22O10 = 542.49
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Flavonoids
    植物来源 The leaves of Garcinia travancorica.
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    GB 1a CFN96934 220611-41-6 1mg QQ客服:2056216494
    GB 1a CFN96934 220611-41-6 5mg QQ客服:2056216494
    GB 1a CFN96934 220611-41-6 10mg QQ客服:2056216494
    GB 1a CFN96934 220611-41-6 20mg QQ客服:2056216494
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • Almansora University (Egypt)
  • Shanghai University of TCM (China)
  • Hamdard University (India)
  • University of Queensland (Australia)
  • University of Melbourne (Australia)
  • Universiti Kebangsaan Malaysia (Malaysia)
  • Centrum Menselijke Erfelijkheid (Belgium)
  • Donald Danforth Plant Science Center (USA)
  • University of Auckland (New Zealand)
  • University of Madras (India)
  • Univerzita Karlova v Praze (Czech Republic)
  • Weizmann Institute of Science (Israel)
  • Fraunhofer-Institut für Molekularbiologie und Angewandte ?kologie IME (Germany)
  • Research Unit Molecular Epigenetics (MEG) (Germany)
  • More...
  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Life Sci.2018, 209:498-506
  • Molecules.2018, 23(3):E615
  • Korea Institute of Oriental Medicine2020, doi: 10.21203.
  • Food Analytical Methods2020, 1-10
  • FEMS Microbiol Lett.2017, 364(11)
  • Food Chem.2019, 274:345-350
  • J Sci Food Agric.2017, 97(5):1656-1662
  • Agronomy2020, 10(10),1489
  • J Med Food.2021, 24(3):209-217.
  • Natural Product Res.&Deve.2022, 1001-6880.
  • J Med Food.2020, 23(6):633-640.
  • Anal Bioanal Chem.2020, 412(12):3005-3015.
  • Molecules.2020, 25(18),4089.
  • Saf Health Work.2019, 10(2):196-204
  • Braz J Med Biol Res.2021, 54(12):e11183.
  • J Cancer.2019, 10(23):5843-5851
  • Front Pharmacol.2022, 13:806869.
  • J of l. Chroma.&Related Tech2020, 43(11-12):414-423.
  • Front Cell Dev Biol.2021, 9:588093.
  • Evid Based Complement Alternat Med.2022, 9767292,2.
  • Heliyon.2023, 9(12):e22932.
  • Applied Biological Chemistry 2021, 64(75)
  • Life (Basel).2021, 11(7):616.
  • ...
  • 生物活性
    Description: GB 1a shows potential in vitro antioxidant activities.
    Targets: Tyrosinase
    In vitro:
    Nat Prod Res. 2016;30(2):232-6.
    Phytochemical analysis and antioxidant potential of the leaves of Garcinia travancorica Bedd.[Pubmed: 25982126 ]

    METHODS AND RESULTS:
    Phytochemical analysis of the leaves of Garcinia travancorica, a hitherto uninvestigated endemic species to the Western Ghats of south India, resulted in isolation and characterisation of the polyisoprenylated benzophenones 7-epi-nemorosone (1) and garcinol (2) along with biflavonoids GB 1a (3), GB-1 (4), GB-2 (5), morelloflavone (6) and morelloflavone-7″-O-β-D-glycoside or fukugiside (7). The compounds were identified using various spectroscopic techniques, mainly through NMR and MS. The methanol extract and the biflavonoids 3, 4, 5 and 7 showed potential in vitro antioxidant activities. The IC50 value of the 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging activity of compound 7 was 8.34 ± 2.12 μg/mL, comparable to that of standard ascorbic acid (3.2 ± 0.50 μg/mL). In the superoxide radical scavenging assay, compound 7 gave IC50 value of 6.95 ± 1.33 μg/mL close to standard ascorbic acid with IC50 value of 5.8 ± 0.25 μg/mL.
    CONCLUSIONS:
    Validated HPTLC estimation revealed G. travancorica as a rich source of morelloflavone-7″-O-β-D-glycoside (7.12% dry wt. leaves).
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 1.8434 mL 9.2168 mL 18.4335 mL 36.867 mL 46.0838 mL
    5 mM 0.3687 mL 1.8434 mL 3.6867 mL 7.3734 mL 9.2168 mL
    10 mM 0.1843 mL 0.9217 mL 1.8434 mL 3.6867 mL 4.6084 mL
    50 mM 0.0369 mL 0.1843 mL 0.3687 mL 0.7373 mL 0.9217 mL
    100 mM 0.0184 mL 0.0922 mL 0.1843 mL 0.3687 mL 0.4608 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    2,3-二羟基金松双黄酮; 2,3-dihydrosciadopitysin CFN96134 34421-19-7 C33H26O10 = 582.6 5mg QQ客服:2056216494
    2,3-二氢罗汉松黄酮A; 2,3-Dihydropodocarpusflavone A CFN96378 852875-96-8 C31H22O10 = 554.5 5mg QQ客服:2056216494
    四氢阿曼托黄素; Tetrahydroamentoflavone CFN98755 48236-96-0 C30H22O10 = 542.5 5mg QQ客服:3257982914
    3',3'''-二柚皮素; 3',3'''-Binaringenin CFN95558 145399-99-1 C30H22O10 = 542.5 5mg QQ客服:2056216494
    穗花杉双黄酮; 阿曼托黄酮; Amentoflavone CFN99526 1617-53-4 C30H18O10 = 538.46 20mg QQ客服:2056216494
    7-去甲基银杏双黄酮; Bilobetin CFN98846 521-32-4 C31H20O10 = 552.5 20mg QQ客服:2159513211
    红杉双黄酮; Sequoiaflavone CFN95642 21763-71-3 C31H20O10 = 552.5 5mg QQ客服:215959384
    苏铁双黄酮; Sotetsuflavone CFN93257 2608-21-1 C31H20O10 = 552.5 5mg QQ客服:3257982914
    银杏素; Ginkgetin CFN90173 481-46-9 C32H22O10 = 566.51 20mg QQ客服:2056216494
    罗汉松黄酮A; Podocarpusflavone A CFN98202 22136-74-9 C31H20O10 = 552.5 5mg QQ客服:3257982914

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