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  • 堪非醇3,4'-二-O-甲醚

    Ermanin

    堪非醇3,4'-二-O-甲醚
    产品编号 CFN98050
    CAS编号 20869-95-8
    分子式 = 分子量 C17H14O6 = 314.3
    产品纯度 >=98%
    物理属性 Yellow powder
    化合物类型 Flavonoids
    植物来源 The herbs of Tanacetum parthenium.
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    堪非醇3,4'-二-O-甲醚 CFN98050 20869-95-8 1mg QQ客服:3257982914
    堪非醇3,4'-二-O-甲醚 CFN98050 20869-95-8 5mg QQ客服:3257982914
    堪非醇3,4'-二-O-甲醚 CFN98050 20869-95-8 10mg QQ客服:3257982914
    堪非醇3,4'-二-O-甲醚 CFN98050 20869-95-8 20mg QQ客服:3257982914
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • Nicolaus Copernicus Uniwersity (Poland)
  • The University of Newcastle (Australia)
  • Fraunhofer-Institut für Molekularbiologie und Angewandte ?kologie IME (Germany)
  • Center for protein Engineering (CIP) (Belgium)
  • Charles University in Prague (Czech Republic)
  • Universidad Industrial de Santander (Colombia)
  • Korea Food Research Institute(KFRI) (Korea)
  • Texas A&M University (USA)
  • University of Toulouse (France)
  • The Vancouver Prostate Centre (VPC) (Canada)
  • University of Leipzig (Germany)
  • Massachusetts General Hospital (USA)
  • Kazusa DNA Research Institute (Japan)
  • University of Auckland (New Zealand)
  • More...
  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Biomolecules.2019, 9(11):E696
  • Nat Prod Sci.2014, 20(3):182-190
  • Free Radic Biol Med.2016, 97:307-319
  • Int Immunopharmacol.2022, 106:108603.
  • ACS Omega.2021, 6(36):23460-23474.
  • Plants (Basel).2021, 10(2):278.
  • J Herbmed Pharmacol.2018, 7(4):280-286
  • Phytomedicine.2018, 40:37-47
  • Oxid Med Cell Longev.2021, 2021:6647107.
  • J Nat Med.2017, 71(4):745-756
  • Drug Des Devel Ther.2023, 17:2461-2479.
  • Int J Vitam Nutr Res.2022, doi: 10.1024.
  • Vojnosanit Pregl2016, 75(00):391-391
  • ScientificWorldJournal.2022, 2022:4806889.
  • Phytomedicine.2019, 57:95-104
  • J Agric Food Chem.2022, 70(51):16176-16187.
  • Industrial Crops and Products2022, 188:115596.
  • Int J Mol Sci.2018, 19(9):E2601
  • Free Radic Biol Med.2017, 112:191-199
  • Dis Markers.2022, 2022:2380879.
  • Journal of Ginseng Research2022, j.jgr.2022.09.005.
  • Drug Test Anal.2018, 10(10):1579-1589
  • Biosci Biotechnol Biochem.2020, 84(3):621-632
  • ...
  • 生物活性
    Description: Ermanin shows anti-inflammatory activity by suppressing the iNOS and COX-2 expression. Ermanin may have anti-HIV-1activity. Ermanin also has a high deterrent activity at 40 ppm against Dione juno larvae.
    Targets: NO | PGE | NOS | COX | HIV | Antifection
    In vitro:
    Planta Med. 2010 May;76(7):721-5.
    Anti-HIV-1 diterpenoids from leaves and twigs of Polyalthia sclerophylla.[Pubmed: 20013639]

    METHODS AND RESULTS:
    Bioassay-guided fractionation and purification of the anti-HIV-1-active MeOH extract from the leaves and twigs of Polyalthia sclerophylla led to the isolation of two new compounds, ENT-kaur-sclerodimer ( 1) and cyclotucanol 3-palmitate ( 2), along with the known ENT-kaur-16-en-19-oic acid ( 3), 15 beta-hydroxy- ENT-kaur-16-en-19-oic acid ( 4), 15 beta-acetoxy- ENT-kaur-16-en-19-oic acid ( 5), 15-oxo- ENT-kaur-16-en-19-oic acid ( 6), 16 alpha,17-dihydroxy- ENT-kauran-19-oic acid ( 7), 16 alpha-hydroxy- ENT-kauran-19-oic acid (xylopic acid) ( 8), a pseudodimer (15 alpha-hydroxy- ENT-kaur-16-en-19-oic acid/17-hydroxy- ENT-kaur-15-en-19-oic acid) ( 9), Ermanin, nicotiflorin, and allantoin.
    CONCLUSIONS:
    Among these isolates, compound 3 was the most active in both anti-syncytium (EC (50) 13.7 microg/mL and selectivity index 3.1) and HIV-1 reverse transcriptase (IC (50) 34.1 microg/mL) assays.
    Phytochemistry, 1991, 30(1):153-5.
    Ermanin: An insect deterrent flavonoid from Passiflora foetida resin.[Reference: WebLink]

    METHODS AND RESULTS:
    Ten flavonoids were isolated from Passiflora foetida L. resin. One of them, ermanin, has a high deterrent activity at 40 ppm against Dione juno larvae.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 3.1817 mL 15.9084 mL 31.8167 mL 63.6335 mL 79.5418 mL
    5 mM 0.6363 mL 3.1817 mL 6.3633 mL 12.7267 mL 15.9084 mL
    10 mM 0.3182 mL 1.5908 mL 3.1817 mL 6.3633 mL 7.9542 mL
    50 mM 0.0636 mL 0.3182 mL 0.6363 mL 1.2727 mL 1.5908 mL
    100 mM 0.0318 mL 0.1591 mL 0.3182 mL 0.6363 mL 0.7954 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    TPCA-1; TPCA-1 CFN60174 507475-17-4 C12H10FN3O2S = 279.29 5mg QQ客服:3257982914
    西伯利亚远志糖A6; Sibiricose A6 CFN90646 241125-75-7 C23H32O15 = 548.5 20mg QQ客服:3257982914
    N-Methyltaxol C ; N-Methyltaxol C CFN89043 153083-53-5 C47H59NO14 = 861.97 5mg QQ客服:215959384
    8-氧代黄连碱; 8-氧黄连碱; 8-Oxycoptisine CFN92158 19716-61-1 C19H13NO5 = 335.3 20mg QQ客服:2159513211

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