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  • Durantoside I

    Durantoside I

    Durantoside I
    产品编号 CFN97726
    CAS编号 53526-67-3
    分子式 = 分子量 C26H32O13 = 552.53
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Iridoids
    植物来源 The herbs of Duranta repens
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    Durantoside I CFN97726 53526-67-3 1mg QQ客服:1413575084
    Durantoside I CFN97726 53526-67-3 5mg QQ客服:1413575084
    Durantoside I CFN97726 53526-67-3 10mg QQ客服:1413575084
    Durantoside I CFN97726 53526-67-3 20mg QQ客服:1413575084
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • University of Madras (India)
  • Universiti Putra Malaysia(UPM) (Malaysia)
  • University of Toulouse (France)
  • Warszawski Uniwersytet Medyczny (Poland)
  • Almansora University (Egypt)
  • Shanghai Institute of Biochemistry and Cell Biology (China)
  • Uniwersytet Jagielloński w Krakowie (Poland)
  • Sanford Burnham Prebys Medical Discovery Institute (USA)
  • The Vancouver Prostate Centre (VPC) (Canada)
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  • University of Minnesota (USA)
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  • University of Limpopo (South Africa)
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  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • FEBS Lett.2015, 589(1):182-7
  • J Nutr Biochem.2022, 107:109064.
  • Molecules2020, 25(4):892
  • Journal of Physiology & Pathology in Korean Medicine.2018, 32(2): 106-112
  • Nutrients.2020, 12(12):3638.
  • Chemistry of Plant Materials.2019, 129-136
  • Molecules.2019, 24(19):E3417
  • J Korean Soc Food Sci Nutr2020, doi: 10.3746.
  • Mol Pharmacol.2021, 99(2):163-174.
  • Phytomedicine.2021, 93:153789.
  • Molecules2021, 26(1),230
  • Front Microbiol.2022, 13:835463.
  • J. of The Korean Society of Food Culture2017, 144-149
  • J Nat Med.2017, 71(2):457-462
  • Phytomedicine.2018, 41:62-66
  • Sci Rep.2021, 11(1):11936.
  • Int Immunopharmacol.2023, 125:111175.
  • Vietnam Journal of Food Control2022, 5(3):pp.390-401.
  • Int. J. Mol. Sci.2022, 23(14),7699;
  • Biomed Pharmacother.2023, 163:114785.
  • Biocell2023, 47(8):1793-1802
  • Plants (Basel).2023, 12(22):3877.
  • Antioxidants (Basel).2021, 10(11): 1802.
  • ...
  • 生物活性
    Description: Durantoside I has inhibitory activity on the growth of lettuce seedling. It also displays DPPH scavenging activity.
    In vitro:
    Industrial Crops & Products,2015, 76(1):653-9.
    Phytochemical and phytotoxic investigation of the flowers from Citharexylum spinosum L.[Reference: WebLink]
    The aim of this study was to assess the phytotoxic potential of flowers of Citharexylum spinosum, as well as to isolate the main bioactive compounds.
    METHODS AND RESULTS:
    Results showed that the ethyl acetate extract induced the highest reduction, showing 100% inhibition of lettuce growth at 6000 ppm. This bioactive ethyl acetate extract was subjected to bio-guided chromatographic separation yielding the acetylated form of a new iridoid glucoside, designated as spinoside (1) together with two acetylated forms (2a) and (2b) of its known analogue Durantoside I (2).
    CONCLUSIONS:
    Their structures were established via their acetylated derivatives by means of spectroscopic and chemical data. The most inhibitory compound on the growth of lettuce seedling was identified to be the durantoside-I tetraacetylated (2b).
    J. Pharm. Res.,2013,7(2):162-6.
    New protein glycation inhibitory free radical scavenging compound from Duranta repens L.[Reference: WebLink]
    Hyperglycemia induced oxidative stress, increased generation of free radicals and free radicals mediated glycation of protein molecules are important events aggravating development of a number of diabetic complications. To identify antiglycation principles with free radicals scavenging activities from traditional oriental medicinal plants.
    METHODS AND RESULTS:
    Biological activity ABTS+ radical scavenging in particular, guided isolation of active compounds was performed from methanolic extract of traditional oriental medicinal plants Duranta repense. Isolated compounds were further studied for their DPPH radical scavenging activity and advanced glycation end-products inhibitory potentials in vitro. Activity guided isolation from methanolic extract of D. repens led to the identification of five iridoids namely Caryoptoside (1), Duraterectoside A (2), Durantoside III (3), Durantoside I (4), Lamiide (7) and two lignans namely (+) 5′Methoxyisolariciresinol (5), (−)5′Methoxyisolariciresinol (6). All the compounds scavenged ABTS+ radical, Caryoptoside (1) and (+) 5′Methoxyisolariciresinol (5) being most potent ABTS+ scavenger (IC50 = 6.0 and 3.1 μg/mL respectively). Only (+) 5′Methoxyisolariciresinol (5) displayed DPPH scavenging activity (IC50 = 70.5 μg/mL). Despite being potent ABTS+ scavenges, iridoid compounds rather augmented glucose induced formation of advanced glycation end-products in bovine serum albumin protein. (+) 5′Methoxyisolariciresinol (5) displayed both, the potent ABTS+ and DPPH scavenging activity however, showed mild (10%) antiglycation activity. On the other hand, (−) isomer of lignin 5′Methoxyisolariciresinol (6) that displayed moderate ABTS+ scavenging activity (IC50 = 42.6 μg/mL) potently inhibited (45%) glucose induced glycation of bovine serum albumin (BSA) protein.
    CONCLUSIONS:
    Methanol extract of D. repense possess potent antioxidant compounds. Iridoids augmented glucose induced glycation of BSA. Lignans displayed antiglycation activity. The (−) isomer of lignan 5′Methoxyisolariciresinol (6) was five times more potent in inhibiting glucose induced generation of AGEs in BSA.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 1.8099 mL 9.0493 mL 18.0986 mL 36.1971 mL 45.2464 mL
    5 mM 0.362 mL 1.8099 mL 3.6197 mL 7.2394 mL 9.0493 mL
    10 mM 0.181 mL 0.9049 mL 1.8099 mL 3.6197 mL 4.5246 mL
    50 mM 0.0362 mL 0.181 mL 0.362 mL 0.7239 mL 0.9049 mL
    100 mM 0.0181 mL 0.0905 mL 0.181 mL 0.362 mL 0.4525 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    Phloyoside II; Phloyoside II CFN91606 158599-51-0 C17H25ClO12 = 456.83 5mg QQ客服:1413575084
    林生续断苷I; Sylvestroside I CFN97081 71431-22-6 C33H48O19 = 748.7 5mg QQ客服:2056216494
    4'-O-反式对香豆酰玉叶金花甙酸甲酯; 4'-O-trans-p-Coumaroylmussaenoside CFN99360 1246012-27-0 C26H32O12 = 536.5 5mg QQ客服:1413575084
    山栀子苷甲酯; Gardoside methyl ester CFN95467 93930-20-2 C17H24O10 = 388.4 10mg QQ客服:3257982914
    野芝麻新苷; Lamiide CFN97765 27856-54-8 C17H26O12 = 422.38 5mg QQ客服:2056216494
    Durantoside I; Durantoside I CFN97726 53526-67-3 C26H32O13 = 552.53 5mg QQ客服:3257982914
    Durantoside II; Durantoside II CFN97727 53526-66-2 C27H34O14 = 582.56 5mg QQ客服:215959384
    胡麻属苷; Sesamoside CFN99274 117479-87-5 C17H24O12 = 420.4 20mg QQ客服:2056216494
    Phlorigidoside C; Phlorigidoside C CFN91608 276691-32-8 C17H24O11 = 404.37 5mg QQ客服:1413575084
    Lamalbid; Lamalbid CFN92847 52212-87-0 C17H26O12 = 422.4 5mg QQ客服:3257982914

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