Info: Read More
  • 中药标准品生产商,产品定制服务
  • 二氢桑色素

    Dihydromorin

    二氢桑色素
    产品编号 CFN99854
    CAS编号 18422-83-8
    分子式 = 分子量 C15H12O7 = 304.3
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Flavonoids
    植物来源 The branches of Morus alba L.
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    二氢桑色素 CFN99854 18422-83-8 1mg QQ客服:1457312923
    二氢桑色素 CFN99854 18422-83-8 5mg QQ客服:1457312923
    二氢桑色素 CFN99854 18422-83-8 10mg QQ客服:1457312923
    二氢桑色素 CFN99854 18422-83-8 20mg QQ客服:1457312923
    存储与注意事项
    1. 在您收到产品后请检查产品。如无问题,请将产品存入冰霜并且样品瓶保持密封,产品可以存放长达24个月(2-8摄氏度)。

    2. 只要有可能,产品溶解后,您应该在同一天应用于您的实验。 但是,如果您需要提前做预实验,或者需要全部溶解,我们建议您将溶液以等分试样的形式存放在-20℃的密封小瓶中。 通常,这些可用于长达两周。 使用前,打开样品瓶前,我们建议您将产品平衡至室温至少1小时。

    3. 需要更多关于溶解度,使用和处理的建议? 请发送电子邮件至:service@chemfaces.com
    订购流程
  • 1. 在线订购
  • 请联系我们QQ客服

  • 2. 电话订购
  • 请拨打电话:
    027-84237683 或 027-84237783

  • 3. 邮件或传真订购
  • 发送电子邮件到: manager@chemfaces.com 或
    发送传真到:027-84254680

  • 提供订购信息
  • 为了方便客户的订购,请需要订购ChemFaces产品的客户,在下单的时候请提供下列信息,以供我们快速为您建立发货信息。
  •  
  • 1. 产品编号(CAS No.或产品名称)
  • 2. 发货地址
  • 3. 联系方法 (联系人,电话)
  • 4. 开票抬头 (如果需要发票的客户)
  • 5. 发票地址(发货地址与发票地址不同)
  • 发货时间
    1. 付款方式为100%预付款客户,我们将在确认收到货款后当天或1-3个工作日发货。

    2. 付款方式为月结的客户,我们承诺在收到订单后当天或1-3个工作日内发货。

    3. 如果客户所需要的产品,需要重新生产,我们有权告知客户,交货时间需要延期。
    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • University of Cincinnati (USA)
  • University of the Basque Country (Spain)
  • University of South Australia (Australia)
  • Instituto Politécnico de Bragan?a (Portugal)
  • Pennsylvania State University (USA)
  • University of Queensland (Australia)
  • Gyeongsang National University (Korea)
  • Julius Kühn-Institut (Germany)
  • Nicolaus Copernicus Uniwersity (Poland)
  • Heinrich-Heine-University Düsseldorf (Germany)
  • The Ohio State University (USA)
  • Martin Luther University of Halle-Wittenberg (Germany)
  • Universiti Sains Malaysia (Malaysia)
  • Aarhus University (Denmark)
  • More...
  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Korean Herb. Med. Inf.2020, 8(2):205-213
  • Kaohsiung J Med Sci.2023, 10.1002/kjm2.12764
  • Pharmacognosy Magazine2017, 13(52):868-874
  • Biochemistry.2018, 57(40):5886-5896
  • J Neuroinflammation.2020, 17(1):75.
  • Biomed Pharmacother.2021, 137:111362.
  • Molecules.2019, 24(16):E3003
  • Natural Product Communications2020, doi: 10.1177.
  • Antioxidants (Basel).2022, 11(12):2411.
  • BMC Plant Biol.2020, 20(1):214.
  • Nutr Cancer.2023, 75(1):376-387.
  • Curr Issues Mol Biol.2023, 45(3):2136-2156.
  • Enzyme Microb Technol.2022, 153:109941.
  • Heliyon.2023, e12778.
  • J of L. Chroma.&Related Tech2017, 252-258
  • Universite de Bordeaux2017, 2017BORD0867
  • African J. Agricultural Research 2017, 12(13):1164-1168
  • Front Microbiol.2020, 11:583594.
  • Molecules.2020 ,25(16):3697.
  • Oncol Lett.2020, 20(4):122.
  • Phytomedicine.2019, 67:153159
  • Sci Rep.2020, 10:4495(2020)
  • Biomed Pharmacother.2019, 111:262-269
  • ...
  • 生物活性
    Description: trans-Dihydromorin is an effective hypopigmenting agent in normal skin cells, hypopigmenting agents effective in melanoma system may not be effective on normal melanocytes, indicating that a non-tumor melanocyte system is more suitable for the screening of hypopigmenting agents. Dihydromorin shows strong mushroom inhibitory activity with IC50 values lower than 50 microM, more potent than (IC50 = 71.6 microM), it may be as an antibrowning agent in food systems.
    Targets: TRP-1 | TRP-2
    In vitro:
    J. Funct. Foods, 2015,13:375-83.
    Oxyresveratrol and trans -dihydromorin from the twigs of Cudrania tricuspidata as hypopigmenting agents against melanogenesis[Reference: WebLink]
    The depigmenting effects of oxyresveratrol and trans- Dihydromorin were investigated in b16F10 cell line and its synergetic melan-a cells, as well as in 3-dimensional skin models.
    METHODS AND RESULTS:
    But their inhibitory effects were different in two cell lines. In b16 cells, oxyresveratrol showed stronger depigmenting effect than trans- Dihydromorin, with greater suppression on tyrosinase activity. Both of them induced post-transcriptional degradations of microphthalmia-associated transcription factor (MITF), leading to significant decreases of tyrosinase related protein 1 (TRP-1) and tyrosinase related protein 2 (TRP-2) production. In melan-a cells, trans- Dihydromorin exhibited stronger inhibition on melanin synthesis. It also induced greater suppression on the levels of tyrosinase, TRP-1 and TRP-2 via MITF down-regulation at both transcription and translation level. Evaluations in artificial skin model also demonstrated the depigmenting effects of trans- Dihydromorin.
    CONCLUSIONS:
    In conclusion, we found that trans -Dihydromorin is an effective hypopigmenting agent in normal skin cells. Furthermore we demonstrated that hypopigmenting agents effective in melanoma system may not be effective on normal melanocytes, indicating that a non-tumor melanocyte system is more suitable for the screening of hypopigmenting agents.
    Mol. Nutr. Food Res., 2008,52(12):1530-8.
    Isolation of tyrosinase inhibitors from Artocarpus heterophyllus and use of its extract as antibrowning agent.[Pubmed: 18683821]
    A new furanoflavone, 7-(2,4-dihydroxyphenyl)-4-hydroxy-2-(2-hydroxy propan-2-yl)-2, 3-dihydrofuro(3, 2-g)chromen-5-one (artocarpfuranol, 1), together with 14 known compounds, Dihydromorin (2), steppogenin (3), norartocarpetin (4), artocarpanone (5), artocarpesin (6), artocarpin (7), cycloartocarpin (8), cycloartocarpesin (9), artocarpetin (10), brosimone I (11), cudraflavone B (12), carpachromene (13), isoartocarpesin (14), and cyanomaclurin (15) were isolated from the wood of Artocarpus heterophyllus.
    METHODS AND RESULTS:
    Their structures were identified by interpretation of MS,( 1)H-NMR,( 13)C-NMR, HMQC, and HMBC spectroscopic data. Among them, compounds 1-6 and 14 showed strong mushroom tyrosinase inhibitory activity with IC(50) values lower than 50 microM, more potent than kojic acid (IC(50) = 71.6 microM), a well-known tyrosinase inhibitor. In addition, extract of A. heterophyllus was evaluated for its antibrowning effect on fresh-cut apple slices. It was discovered that fresh-cut apple slices treated by dipping in solution of 0.03 or 0.05% of A. heterophyllus extract with 0.5% ascorbic acid did not undergo any substantial browning reaction after storage at room temperature for 24 h. The antibrowning effect was significantly better than samples treated with the extract (0.03 or 0.05%) or ascorbic acid (0.5%) alone.
    CONCLUSIONS:
    The results provide preliminary evidence supporting the potential of this natural extract as antibrowning agent in food systems.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 3.2862 mL 16.4312 mL 32.8623 mL 65.7246 mL 82.1558 mL
    5 mM 0.6572 mL 3.2862 mL 6.5725 mL 13.1449 mL 16.4312 mL
    10 mM 0.3286 mL 1.6431 mL 3.2862 mL 6.5725 mL 8.2156 mL
    50 mM 0.0657 mL 0.3286 mL 0.6572 mL 1.3145 mL 1.6431 mL
    100 mM 0.0329 mL 0.1643 mL 0.3286 mL 0.6572 mL 0.8216 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    二氢柽柳黄素; Dihydrotamarixetin CFN97194 70411-27-7 C16H14O7 = 318.3 5mg QQ客服:2056216494
    艾纳香素B; Blumeatin B CFN97274 79995-67-8 C17H16O7 = 332.3 5mg QQ客服:1413575084
    刺槐亭; Dihydrorobinetin CFN98671 4382-33-6 C15H12O7 = 304.3 5mg QQ客服:1413575084
    蛇葡萄素; 二氢杨梅素; Ampelopsin CFN98326 27200-12-0 C15H12O8 = 320.3 20mg QQ客服:215959384
    Sepinol; Sepinol CFN97204 72061-63-3 C16H14O7 = 318.3 5mg QQ客服:3257982914
    6-甲基二氢槲皮素; Cedeodarin CFN97912 31076-39-8 C16H14O7 = 318.3 5mg QQ客服:2159513211
    雪松素; Cedrin CFN97872 75513-81-4 C16H14O8 = 334.3 5mg QQ客服:3257982914
    (-)-二氢槲皮素; (-)-Dihydroquercetin CFN92413 111003-33-9 C15H12O7 = 304.3 5mg QQ客服:1413575084
    花旗松素; Taxifolin CFN98734 480-18-2 C15H12O7 = 304.3 20mg QQ客服:1457312923
    李属素; Padmatin CFN97280 80453-44-7 C16H14O7 = 318.3 5mg QQ客服:1457312923

    信息支持


    公司简介
    订购流程
    付款方式
    退换货政策

    ChemFaces提供的产品仅用于科学研究使用,不用于诊断或治疗程序。

    联系方式


    电机:027-84237783
    传真:027-84254680
    在线QQ: 1413575084
    E-Mail:manager@chemfaces.com

    湖北省武汉沌口经济技术开区车城南路83号1号楼第三层厂房


    ChemFaces为科学家,科研人员与企业提供快速的产品递送。我们通过瑞士SGS ISO 9001:2008质量体系认证天然化合物与对照品的研发和生产