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  • 松柏醇; 反式-3-(4-羟基-3-甲氧基苯基)-2-丙烯-1-醇

    • 松柏醇; 反式-3-(4-羟基-3-甲氧基苯基)-2-丙烯-1-醇

    Coniferyl alcohol

    松柏醇; 反式-3-(4-羟基-3-甲氧基苯基)-2-丙烯-1-醇
    		产品编号 CFN97760
    CAS编号 32811-40-8
    分子式 = 分子量 C10H12O3 = 180.20
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Phenylpropanoids
    植物来源 The herbs of Acanthopanax gracilistylus
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    松柏醇; 反式-3-(4-羟基-3-甲氧基苯基)-2-丙烯-1-醇 CFN97760 32811-40-8 10mg QQ客服：2056216494
    松柏醇; 反式-3-(4-羟基-3-甲氧基苯基)-2-丙烯-1-醇 CFN97760 32811-40-8 20mg QQ客服：2056216494
    松柏醇; 反式-3-(4-羟基-3-甲氧基苯基)-2-丙烯-1-醇 CFN97760 32811-40-8 50mg QQ客服：2056216494
    松柏醇; 反式-3-(4-羟基-3-甲氧基苯基)-2-丙烯-1-醇 CFN97760 32811-40-8 100mg QQ客服：2056216494
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
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    • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Applied Biological Chemistry2022, 65(12)
  • Trop J Pharm Res.2023, 22(3):283-288.
  • Carbohydrate Polymer Technologies & App.2021, 2:100049.
  • Institut Pasteur Korea2020, doi: 10.21203.
  • Toxins (Basel).2022, 14(12):824.
  • J of the Society of Cosmetic Scientists of Korea2018, 44(4):407-417
  • Molecules.2022, 27(7):2093.
  • Curr Res Virol Sci.2022, 3:100019.
  • Agronomy2022, 12(10), 2426.
  • Cell Physiol Biochem.2017, 43(4):1425-1435
  • Molecules.2019, 24(10):E1926
  • Sci Rep.2017, 7(1):3249
  • Plant Cell Tiss Org2017, 479-486
  • Molecules.2020, 25(21):5087.
  • Biomed Pharmacother.2019, 111:262-269
  • BMC Complement Med Ther. 2020, 20(1):94.
  • J Mol Med (Berl).2018, 96(7):661-672
  • J Nat Prod.2021, 84(9):2544-2553.
  • J Biomol Struct Dyn.2023, 1-21.
  • Biosci Biotechnol Biochem.2021, 85(10):2153-2160.
  • Int Immunopharmacol.2019, 71:361-371
  • Chemistry of Plant Materials.2016, 33-46
  • Int. J. Mol. Sci.2022, 23(8), 4130.
  • ...
    • 生物活性
    Description: Coniferyl alcohol restores the growth of KI-treated BY-2 cells and N. benthamiana seedlings, at high concentrations is toxic to plant cells.
    In vitro:
    Planta. 2015 Jun 25.
    Coniferyl alcohol hinders the growth of tobacco BY-2 cells and Nicotiana benthamiana seedlings.[Pubmed: 26108783]
    Externally added Coniferyl alcohol at high concentrations reduces the growth of Nicotiana cells and seedlings. Coniferyl alcohol is metabolized by BY-2 cells to several compounds. Coniferyl alcohol (CA) is a common monolignol and a building block of lignin. The toxicity of monolignol alcohols has been stated in the literature, but there are only few studies suggesting that this is true.
    METHODS AND RESULTS:
    We investigated the physiological effects of Coniferyl alcohol on living plant cells in more detail. Tobacco (Nicotiana tabacum) Bright yellow-2 cells (BY-2) and Nicotiana benthamiana seedlings both showed concentration-dependent growth retardation in response to 0.5-5 mM Coniferyl alcohol treatment. In some cases, Coniferyl alcohol addition caused cell death in BY-2 cultures, but this response was dependent on the growth stage of the cells. Based on LC-MS/MS analysis, BY-2 cells did not accumulate the externally supplemented Coniferyl alcohol, but metabolized it to ferulic acid, ferulic acid glycoside, coniferin, and to some other phenolic compounds. In addition to growth inhibition, Coniferyl alcohol caused the formation of a lignin-like compound detected by phloroglucinol staining in N. benthamiana roots and occasionally in BY-2 cells. To prevent this, we added potassium iodide (KI, at 5 mM) to overcome the peroxidase-mediated Coniferyl alcohol polymerization to lignin. KI had, however, toxic effects on its own: in N. benthamiana seedlings, it caused reduction in growth; in BY-2 cells, reduction in growth and cell viability. Surprisingly, Coniferyl alcohol restored the growth of KI-treated BY-2 cells and N. benthamiana seedlings.
    CONCLUSIONS:
    Our results suggest that Coniferyl alcohol at high concentrations is toxic to plant cells.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 5.5494 mL 27.7469 mL 55.4939 mL 110.9878 mL 138.7347 mL
    5 mM 1.1099 mL 5.5494 mL 11.0988 mL 22.1976 mL 27.7469 mL
    10 mM 0.5549 mL 2.7747 mL 5.5494 mL 11.0988 mL 13.8735 mL
    50 mM 0.111 mL 0.5549 mL 1.1099 mL 2.2198 mL 2.7747 mL
    100 mM 0.0555 mL 0.2775 mL 0.5549 mL 1.1099 mL 1.3873 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    3-苯基-2-丙烯-1-醇； 反式-肉桂醇; 3-Phenyl-2-propen-1-ol CFN98675 4407-36-7 C9H10O = 134.2 5mg QQ客服：1413575084
    乙酸肉桂酯； 乙酰肉桂醇; Cinnamyl acetate CFN98057 21040-45-9 C11H12O2 = 176.2 5mg QQ客服：1457312923
    3-(4-羟基苯基)-1-丙醇; 3-(4-Hydroxyphenyl)-1-propanol CFN99037 10210-17-0 C9H12O2 = 152.2 5mg QQ客服：1457312923
    对羟基肉桂醇; p-Coumaryl alcohol CFN96011 3690-05-9 C9H10O2 = 150.2 5mg QQ客服：215959384
    4-Methoxycinnamyl alcohol; 4-Methoxycinnamyl alcohol CFN89230 53484-50-7 C10H12O2 = 164.20 5mg QQ客服：2159513211
    trans-3,4-Methylenedioxycinnamyl alcohol; trans-3,4-Methylenedioxycinnamyl alcohol CFN92410 58095-76-4 C10H10O3 = 178.2 5mg QQ客服：2159513211
    松柏醇; 反式-3-(4-羟基-3-甲氧基苯基)-2-丙烯-1-醇; Coniferyl alcohol CFN97760 32811-40-8 C10H12O3 = 180.20 20mg QQ客服：2056216494
    二氢松柏醇 ; Dihydroconiferyl alcohol CFN96742 2305-13-7 C10H14O3 = 182.21 5mg QQ客服：2056216494
    γ-甲氧基异丁子香酚; Gamma-Methoxyisoeugenol CFN96094 63644-71-3 C11H14O3 = 194.2 20mg QQ客服：2056216494
    乙酸异丁香酚酯 ; Acetylisoeugenol CFN96771 93-29-8 C12H14O3 = 206.24 20mg QQ客服：2056216494

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