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  • 4-甲氧基-9,10-二氢菲-2,7-二醇

    Coelonin

    4-甲氧基-9,10-二氢菲-2,7-二醇
    产品编号 CFN92693
    CAS编号 82344-82-9
    分子式 = 分子量 C15H14O3 = 242.3
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Phenols
    植物来源 The herbs of Bletilla striata
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    4-甲氧基-9,10-二氢菲-2,7-二醇 CFN92693 82344-82-9 1mg QQ客服:3257982914
    4-甲氧基-9,10-二氢菲-2,7-二醇 CFN92693 82344-82-9 5mg QQ客服:3257982914
    4-甲氧基-9,10-二氢菲-2,7-二醇 CFN92693 82344-82-9 10mg QQ客服:3257982914
    4-甲氧基-9,10-二氢菲-2,7-二醇 CFN92693 82344-82-9 20mg QQ客服:3257982914
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • Periyar University (India)
  • Helmholtz Zentrum München (Germany)
  • Molecular Biology Institute of Barcelona (IBMB)-CSIC (Spain)
  • Universidade Federal de Goias (UFG) (Brazil)
  • Technical University of Denmark (Denmark)
  • Srinakharinwirot University (Thailand)
  • Leibniz-Institut für Pflanzenbiochemie (IPB) (Germany)
  • Max-Planck-Insitut (Germany)
  • Charles Sturt University (Denmark)
  • Biotech R&D Institute (USA)
  • Institute of Chinese Materia Medica (China)
  • Osmania University (India)
  • St. Jude Children Research Hospital (USA)
  • Imperial College London (United Kingdom)
  • More...
  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Oncotarget.2016, 8(51):88386-88400
  • Anal Bioanal Chem.2018, 410(5):1561-1569
  • Phytother Res.2019, 33(4):1104-1113
  • J Mol Recognit.2020, 33(2):e2819
  • Nat Commun.2023, 14(1):4540.
  • Scientific World Journal.2014, 2014:654193
  • The Malaysian journal of pathology2019, 41(3):243-251
  • J Appl Biol Chem2023, 66:455−461
  • J Sep Sci.2018, 41(7):1682-1690
  • Molecules2020, 25(4):892
  • Biomed Pharmacother.2021, 137:111362.
  • Acta Edulis Fungi2020, 27(02):63-76.
  • Molecules.2020, 25(20):4851.
  • Front Cell Infect Microbiol.2018, 8:292
  • Evid Based Complement Alternat Med.2018, 2018:4580627
  • Planta Med.2022, 88(9-10):794-804.
  • Molecules.2020, 25(3):734
  • Nutrients2022, 14(14)2929
  • J. Pharm. Res. Int.2022, 34(58): pp.1-14.
  • Nanjing University of Chinese Medicine2022, 345930.
  • Plos One.2020, 10.1371
  • Processes2022, 10(10), 2008.
  • Front Pharmacol.2017, 8:205
  • ...
  • 生物活性
    Description: Coelonin shows moderate cytotoxic activity against HepG2 cells.
    In vitro:
    Nat Prod Res. 2017 May 29:1-4.
    Phenanthrenes from Arundina graminifolia and in vitro evaluation of their antibacterial and anti-haemolytic properties.[Pubmed: 28553728 ]
    Chemical investigation and activity test of Arundina graminifolia led to the isolation of six phenanthrenes: blestriarene A (1), shancidin (2), densiflorol B (3), ephemeranthoquinone (4), coelonin (5) and lusianthridin (6).
    METHODS AND RESULTS:
    The isolated compounds demonstrated antibacterial and anti-haemolytic activities. It was found that compounds 1 and 2 had medium antibacterial activity against Staphylococcus aureus, Bacillus subtilis and Escherichia coli, with MICs of 20-40 μg/mL and MBCs of 40-320 μg/mL. Bactericidal mechanisms were explored. Rupture of cell wall and membrane and leakage of nuclear mass were observed by transmission electron microscopy (TEM). Moreover, compounds 1-3 attenuated the erythrocyte damage.
    CONCLUSIONS:
    Compounds 1 and 2 showed significant anti-haemolytic activity with inhibition rate about 50% at 16 μg/mL.
    Nat Prod Res. 2017 Jul;31(13):1518-1522.
    Phenolic compounds from the stems of Flickingeria fimbriata.[Pubmed: 28278646]
    Chemical investigation of Flickingeria fimbriata (Bl.) Hawkes (Orchidaceae) resulted in the isolation and identification of one new dihydrophenanthrene, 1,2,5,6,7-pentamethoxy-9,10-dihydrophenanthrene (1), together with seven known dihydrophenanthrenes, erianthridin (2), coelonin (3), 4-methoxy-9,10-dihydrophenanthrene-1,2,7-triol (4), lusianthridin (5), ephemeranthol A (6), flavanthridin (7) and hircinol (8), four known phenanthrenes, epheranthol B (9), nudol (10), denthyrsinin (11) and confusarin (12), and one known bibenzyl, batatasin III (13).
    METHODS AND RESULTS:
    The structure of the new compound was elucidated by spectroscopic analysis (HRMS, 1D and 2D NMR). All the compounds were isolated from F. fimbriata for the first time except for compounds 5 and 12, and compounds 1, 3, 4, 8, 10, 11 and 13 were obtained from this genus for the first time. Compounds 1-4 showed moderate cytotoxic activity against HepG2 cells.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 4.1271 mL 20.6356 mL 41.2712 mL 82.5423 mL 103.1779 mL
    5 mM 0.8254 mL 4.1271 mL 8.2542 mL 16.5085 mL 20.6356 mL
    10 mM 0.4127 mL 2.0636 mL 4.1271 mL 8.2542 mL 10.3178 mL
    50 mM 0.0825 mL 0.4127 mL 0.8254 mL 1.6508 mL 2.0636 mL
    100 mM 0.0413 mL 0.2064 mL 0.4127 mL 0.8254 mL 1.0318 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    (Z)-3-甲氧基-5-(2-苯乙烯基)苯酚; (Z)-3-Hydroxy-5-methoxystilbene CFN96398 143207-76-5 C15H14O2 = 226.3 5mg QQ客服:3257982914
    新化合物VII; New compound 7 CFN95330 N/A C15H14O2 = 226.3 5mg QQ客服:215959384
    Lusianthridin; Lusianthridin CFN92784 87530-30-1 C15H14O3 = 242.3 5mg QQ客服:2056216494
    4-甲氧基-9,10-二氢菲-2,7-二醇; Coelonin CFN92693 82344-82-9 C15H14O3 = 242.3 5mg QQ客服:3257982914
    黄菲灵; Flavidinin CFN92692 83925-00-2 C16H14O3 = 254.3 5mg QQ客服:3257982914
    Agrostophyllidin; Agrostophyllidin CFN92691 178439-50-4 C17H16O4 = 284.3 5mg QQ客服:3257982914
    Phoyunnanin C; Phoyunnanin C CFN92781 956344-38-0 C30H26O6 = 482.5 5mg QQ客服:2159513211
    4-甲氧基菲-2,7-二醇; Flavanthrin CFN92782 120090-80-4 C30H26O6 = 482.5 5mg QQ客服:2159513211
    Diosniposide B; Diosniposide B CFN95333 N/A C22H26O10 = 450.4 5mg QQ客服:1457312923
    去氢厄弗酚,去氢灯心草二酚; Dehydroeffusol CFN90814 137319-34-7 C17H14O2 = 250.3 10mg QQ客服:1413575084

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