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  • 腰果酚(C15:1)

    Cardanol (C15:1)

    腰果酚(C15:1)
    产品编号 CFN92848
    CAS编号 501-26-8
    分子式 = 分子量 C21H34O = 302.3
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Phenols
    植物来源 The fruits of Ginkgo biloba
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    腰果酚(C15:1) CFN92848 501-26-8 1mg QQ客服:2159513211
    腰果酚(C15:1) CFN92848 501-26-8 5mg QQ客服:2159513211
    腰果酚(C15:1) CFN92848 501-26-8 10mg QQ客服:2159513211
    腰果酚(C15:1) CFN92848 501-26-8 20mg QQ客服:2159513211
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
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  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • J Cell Physiol.2020, 10.1002
  • Chem Pharm Bull (Tokyo).2019, 67(11):1242-1247
  • Int J Mol Sci.2021, 22(2):770.
  • BMC Complement Altern Med.2019, 19(1):339
  • Eur J Pharmacol.2021, 906:174220.
  • Molecules2022, 27(9):2613.
  • Int J Mol Sci.2021, 22(11):5503.
  • Oncotarget.2015, 6(31):30831-49
  • J Cell Mol Med.2020, 24(21):12308-12317.
  • Cell Metab.2020, S1550-4131(20)30002-4
  • Phytomedicine.2022, 100:154085.
  • Korean Journal of Pharmacognosy.2020, 51(2):100-106
  • Phytomedicine.2020, 79, 153351
  • Korean j.of Pharm.2017, 70-76
  • Horticulturae2020, 6(4),76.
  • J Ethnopharmacol.2016, 192:370-381
  • In Vitro Cellular & Developmental Biology - Plant2022, 58:972-988.
  • Biol Pharm Bull.2020, 43(10):1534-1541.
  • Malaysian J of Fundamental and Applied Sciences 2018, 14(3):368-373
  • Chemistry of Natural Compounds2018, 204-206
  • FEBS Lett.2015, 589(1):182-7
  • Biol Pharm Bull.2018, 41(1):65-72
  • FEMS Microbiol Lett.2017, 364(11)
  • ...
  • 生物活性
    Description: Cardanol (C15:1) possesses the same side chain as anacardic acid (C15:1), acted neither as a substrate nor as an inhibitor of lipoxygenase-1.
    In vitro:
    J Agric Food Chem. 2005 Jun 1;53(11):4350-4.
    Lipoxygenase inhibitory activity of anacardic acids.[Pubmed: 15913294 ]

    METHODS AND RESULTS:
    6[8'(Z)-pentadecenyl]salicylic acid, otherwise known as anacardic acid (C15:1), inhibited the linoleic acid peroxidation catalyzed by soybean lipoxygenase-1 (EC 1.13.11.12, type 1) with an IC50 of 6.8 microM. The inhibition of the enzyme by anacardic acid (C15:1) is a slow and reversible reaction without residual activity. The inhibition kinetics analyzed by Dixon plots indicates that anacardic acid (C15:1) is a competitive inhibitor and the inhibition constant, KI, was obtained as 2.8 microM. Although anacardic acid (C15:1) inhibited the linoleic acid peroxidation without being oxidized, 6[8'(Z),11'(Z)-pentadecadienyl]salicylic acid, otherwise known as anacardic acid (C15:2), was dioxygenated at low concentrations as a substrate. In addition, anacardic acid (C15:2) was also found to exhibit time-dependent inhibition of lipoxygenase-1.
    CONCLUSIONS:
    The alk(en)yl side chain of anacardic acids is essential to elicit the inhibitory activity. However, the hydrophobic interaction alone is not enough because Cardanol (C15:1), which possesses the same side chain as anacardic acid (C15:1), acted neither as a substrate nor as an inhibitor.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 3.308 mL 16.5399 mL 33.0797 mL 66.1594 mL 82.6993 mL
    5 mM 0.6616 mL 3.308 mL 6.6159 mL 13.2319 mL 16.5399 mL
    10 mM 0.3308 mL 1.654 mL 3.308 mL 6.6159 mL 8.2699 mL
    50 mM 0.0662 mL 0.3308 mL 0.6616 mL 1.3232 mL 1.654 mL
    100 mM 0.0331 mL 0.1654 mL 0.3308 mL 0.6616 mL 0.827 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    腰果酚(C15:1); Cardanol (C15:1) CFN92848 501-26-8 C21H34O = 302.3 5mg QQ客服:3257982914
    漆酚(15:1); Urushiol (15:1) CFN70344 35237-02-6 C21H34O2 = 318.5 5mg QQ客服:2056216494
    漆酚(15:2); Urushiol (15:2) CFN70456 83258-37-1 C21H32O2 = 316.5 5mg QQ客服:2056216494
    漆酚(15:3); Urushiol (15:3) CFN70457 83543-37-7 C21H30O2 = 314.5 5mg QQ客服:215959384
    5-(Z-十七-8-烯基)邻苯二酚; 5-(Z-heptadec-8-enyl) resorcinol CFN98859 52483-19-9 C23H38O2 = 346.6 5mg QQ客服:215959384
    5-十七烷基间苯二酚; 5-Heptadecylresorcinol CFN97874 41442-57-3 C23H40O2 = 348.6 5mg QQ客服:1457312923
    5-二十三烷基间苯二酚; 5-Tricosyl-1,3-benzenediol CFN97188 70110-60-0 C29H52O2 = 432.7 5mg QQ客服:3257982914
    5-二十五烷基间苯二酚; 5-Pentacosylresorcinol CFN97189 70110-61-1 C31H56O2 = 460.8 5mg QQ客服:215959384
    3-甲氧基-5-二十一烷基苯酚; 3-Methoxy-5-heneicosylphenol CFN99380 126882-76-6 C28H50O2 = 418.7 5mg QQ客服:1413575084
    Ganomycin I; Ganomycin I CFN92595 1191255-15-8 C21H26O4 = 342.4 5mg QQ客服:215959384

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