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  • 构树宁B

    Broussonin B

    构树宁B
    产品编号 CFN97695
    CAS编号 73731-86-9
    分子式 = 分子量 C16H18O3 = 258.32
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Phenols
    植物来源 The branches of Broussonetia papyrifera.
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    构树宁B CFN97695 73731-86-9 1mg QQ客服:1413575084
    构树宁B CFN97695 73731-86-9 5mg QQ客服:1413575084
    构树宁B CFN97695 73731-86-9 10mg QQ客服:1413575084
    构树宁B CFN97695 73731-86-9 20mg QQ客服:1413575084
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
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  • University of Leipzig (Germany)
  • The Institute of Cancer Research (United Kingdom)
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  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Vietnam Journal of Food Control.2022, 5(3):pp.488-497.
  • Cancer Sci.2022, 113(4):1406-1416.
  • J Int Med Res.2021, 49(7):3000605211032849.
  • Int J Mol Sci.2022, 23(11):6104.
  • Nat Plants.2016, 3:16205
  • Int J Mol Sci.2021, 22(16):8604.
  • Int J Mol Sci.2018, 19(9):E2601
  • EXCLI J.2023, 22:482-498.
  • Applied Biological Chemistry2022, 71:s13765-022-00743-5.
  • FEBS Lett.2015, 589(1):182-7
  • Turkish Journal of Pharmaceutical Sciences2022, DOI: 10.4274
  • J Anal Methods Chem.2022, 2022:2229500.
  • Biol Pharm Bull.2018, 41(1):65-72
  • Arch Biochem Biophys.2020, 687:108363.
  • Industrial Crops and Products2022, 186:115298
  • Sci Rep.2018, 8(1)
  • J Med Food.2016, 19(12):1155-1165
  • Nat Prod Communications2018, 10.1177
  • Phytomedicine.2019, 58:152893
  • Mol Med Rep.2014, 9(5):1653-9
  • Molecules.2017, 22(12)
  • Int Immunopharmacol.2022, 106:108603.
  • Chem Biol Interact.2018, 290:44-51
  • ...
  • 生物活性
    Description: Broussonins A and B, new phytoalexins from diseased paper mulberry. Broussonin B can induce neurite outgrowth in PC-12 cells at concentration of 50 microg/ml, and show moderate inhibitory activities against a chymotrypsin-like activity of the proteasome.Broussonin B also can significantly inhibit adipocyte differentiation in 3T3-L1 cells as measured fat accumulation using Oil Red O assay.
    In vitro:
    Biol Pharm Bull. 2005 Sep;28(9):1798-800.
    7-hydroxy-3-(4-hydroxybenzyl)chroman and broussonin b: neurotrophic compounds, isolated from Anemarrhena asphodeloides BUNGE, function as proteasome inhibitors.[Pubmed: 16141565 ]

    METHODS AND RESULTS:
    The extract of Anemarrhenae Rhizoma (rhizomes of Anemarrhena asphodeloides BUNGE) showed neurotrophic activity toward rat pheochromocytoma (PC-12) cells. Bioassay-guided purification afforded four compounds, 2,6,4'-trihydroxy-4-methoxybenzophenone (1), 7-hydroxy-3-(4-hydroxybenzyl)chroman (2), broussonin B (3), and cis-hinokiresinol (4).
    CONCLUSIONS:
    Compounds 1-3 induced neurite outgrowth in PC-12 cells at concentration of 50 microg/ml, while 4 was less active. In addition, compounds 2-4 showed moderate inhibitory activities against a chymotrypsin-like activity of the proteasome.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 3.8712 mL 19.3558 mL 38.7117 mL 77.4234 mL 96.7792 mL
    5 mM 0.7742 mL 3.8712 mL 7.7423 mL 15.4847 mL 19.3558 mL
    10 mM 0.3871 mL 1.9356 mL 3.8712 mL 7.7423 mL 9.6779 mL
    50 mM 0.0774 mL 0.3871 mL 0.7742 mL 1.5485 mL 1.9356 mL
    100 mM 0.0387 mL 0.1936 mL 0.3871 mL 0.7742 mL 0.9678 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    1-(4-羟基-2-甲氧基苯基)-3-(4-羟基-3-异戊烯基苯基)丙烷; 1-(4-Hydroxy-2-methoxyphenyl)-3-(4-hydroxy-3-prenylphenyl)propane CFN98607 376362-03-7 C21H26O3 = 326.4 5mg QQ客服:215959384
    1-羟基-1-(4-羟基-2-甲氧基苯基)-3-(4-羟基苯基)-2-丙酮; 1-Hydroxy-1-(4-hydroxy-2-methoxyphenyl)-3-(4-hydroxyphenyl)propan-2-one CFN97846 117614-84-3 C16H16O5 = 288.3 5mg QQ客服:3257982914
    Puerol A; Puerol A CFN96269 152784-32-2 C17H14O5 = 298.3 5mg QQ客服:3257982914
    (+)-Puerol B 2''-O-glucoside; (+)-Puerol B 2''-O-glucoside CFN97602 868409-19-2 C24H26O10 = 474.46 10mg QQ客服:2056216494
    Puerol B; Puerol B CFN95155 112343-17-6 C18H16O5 = 312.3 5mg QQ客服:1457312923
    Specioside B; Specioside B CFN95165 126589-95-5 C23H24O10 = 460.4 5mg QQ客服:2159513211
    葛根苷A; Pueroside A CFN95177 100692-52-2 C29H34O14 = 606.6 5mg QQ客服:1457312923
    葛根苷C; Pueroside C CFN95156 112343-16-5 C24H26O10 = 474.5 5mg QQ客服:2159513211
    葛根苷B; Pueroside B CFN95141 100692-54-4 C30H36O15 = 636.6 10mg QQ客服:3257982914
    构树宁B; Broussonin B CFN97695 73731-86-9 C16H18O3 = 258.32 10 mg QQ客服:1457312923

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