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  • 苯甲酰氧化芍药苷

    Benzoyloxypeoniflorin

    苯甲酰氧化芍药苷
    产品编号 CFN90662
    CAS编号 72896-40-3
    分子式 = 分子量 C30H32O13 = 600.57
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Monoterpenoids
    植物来源 The roots of Paeonia lactiflora Pall.
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    苯甲酰氧化芍药苷 CFN90662 72896-40-3 10mg QQ客服:1457312923
    苯甲酰氧化芍药苷 CFN90662 72896-40-3 20mg QQ客服:1457312923
    苯甲酰氧化芍药苷 CFN90662 72896-40-3 50mg QQ客服:1457312923
    苯甲酰氧化芍药苷 CFN90662 72896-40-3 100mg QQ客服:1457312923
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • University of Cincinnati (USA)
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  • Yale University (USA)
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  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • J Mol Med (Berl).2018, 96(7):661-672
  • Antioxidants (Basel).2022, 11(8):1471.
  • Invest New Drugs.2017, 35(2):166-179
  • J Sep Sci.2018, 41(9):1938-1946
  • South African J of Botany2020, 135:50-57
  • J-STAGE2015, 249-255
  • Evid Based Complement Alternat Med.2021, 2021:6687513.
  • Natural Product Communications2021, 16(9):1-10.
  • J of Pharmaceutical Analysis2020, doi: 10.1016
  • Exp Mol Med.2020, 52(4):629-642.
  • Oncol Rep.2021, 46(1):143.
  • Integr Med Res.2017, 6(4):395-403
  • J Mol Recognit.2020, 33(2):e2819
  • Processes2021, 9(5),831.
  • Int J Mol Sci.2019, 20(16):E4015
  • Journal of Ginseng Research2019, 10.1016
  • Processes2021, 9(11),2065.
  • Nat Commun.2021, 12(1):681.
  • Anticancer Res.2018, 38(4):2127-2135
  • Int Immunopharmacol.2021, 100:108073.
  • Front Pharmacol.2019, 10:1025
  • J Nat Med.2022, 76(1):59-67.
  • Ecol Evol.2022, 12(11):e9459.
  • ...
  • 生物活性
    Description: Benzoyloxypeoniflorin contributes to improving blood circulation through their inhibitory effects on both platelet aggregation and blood coagulation.
    Targets: PAFR
    In vitro:
    Pharmazie. 2010 Aug;65(8):624-8.
    Platelet anti-aggregatory and blood anti-coagulant effects of compounds isolated from Paeonia lactiflora and Paeonia suffruticosa.[Pubmed: 20824965]
    The roots of two Paeoniaceae family members have long been used as traditional medicines in Korea, China, and Japan. Dry roots of Paeonia lactiflora and dry root bark of P. suffruticosa are used under the traditional names of Paeoniae Radix and Moutan Cortex, respectively.
    METHODS AND RESULTS:
    Both Paeoniae Radix and Moutan Cortex have been used as remedies for cardiovascular diseases, for improving blood circulation, or for other uses. It was postulated that both plants may contain common active constituents that contribute to inhibiting blood coagulation and/or platelet aggregation. Eighteen compounds, which have been reported to be present in both plant medicines, were evaluated for their effects on platelet aggregation and blood coagulation. Paeonol (5), paeoniflorin (9), benzoylpaeoniflorin (11), and Benzoyloxypeoniflorin (12) were found to be the major common active constituents and they would collectively contribute to improving blood circulation through their inhibitory effects on both platelet aggregation and blood coagulation. In addition, methylgallate (4), (+)-catechin (7), paeoniflorigenone (8), galloylpaeoniflorin (13), and daucosterol (16) may also take part in improving blood circulation by inhibiting ether platelet aggregation and/or blood coagulation.
    Evid Based Complement Alternat Med . 2019 Mar 3;2019:6150357.
    The Screening Research of NF- κ B Inhibitors from Moutan Cortex Based on Bioactivity-Integrated UPLC-Q/TOF-MS[Pubmed: 30941197]
    Abstract Inflammation is a common and important pathological process, and nuclear factor-κB (NF-κB) is a key mediator of it. Moutan Cortex (MC), the dried root cortex of Paeonia suffruticosa Andr., is widely used as a remedy for the treatment of inflammatory diseases in Asian region. However, there are few studies on the systematic identification of NF-κB inhibitors of MC. In this study, the effect of inhibiting NF-κB activation of MC was assessed at the cellular level using a tumor necrosis factor-α (TNF-α) induced inflammatory model. Subsequently, ultra-performance liquid chromatography-quadrupole/time of flight-mass spectrometry (UPLC-Q/TOF-MS) combined with biological activity assay was established to screen and identify potential anti-inflammatory ingredients in MC. The results revealed that MC significantly inhibited the activation of NF-κB. Seven potential NF-κB inhibitors were screened from MC, including oxypaeoniflorin, paeoniflorin, galloylpaeoniflorin, benzoyloxypaeoniflorin, mudanpioside C, gallic acid, and paeonol. Among them, the NF-κB inhibitor activity of galloylpaeoniflorin, benzoyloxypaeoniflorin, and mudanpioside C is first reported here. In conclusion, the anti-inflammatory activity of MC was associated with the seven components mentioned above. And the bioactivity-integrated UPLC-Q/TOF which contains both chemical and bioactive details is suitable for screening active ingredients from natural medicines.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 1.6651 mL 8.3254 mL 16.6508 mL 33.3017 mL 41.6271 mL
    5 mM 0.333 mL 1.6651 mL 3.3302 mL 6.6603 mL 8.3254 mL
    10 mM 0.1665 mL 0.8325 mL 1.6651 mL 3.3302 mL 4.1627 mL
    50 mM 0.0333 mL 0.1665 mL 0.333 mL 0.666 mL 0.8325 mL
    100 mM 0.0167 mL 0.0833 mL 0.1665 mL 0.333 mL 0.4163 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    苯甲酰氧化芍药苷; Benzoyloxypeoniflorin CFN90662 72896-40-3 C30H32O13 = 600.57 20mg QQ客服:2159513211
    牡丹皮苷C; Mudanpioside C CFN90661 172760-03-1 C30H32O13 = 600.57 20mg QQ客服:3257982914
    没食子酰芍药苷; Galloylpaeoniflorin CFN90831 122965-41-7 C30H32O15 = 632.6 10mg QQ客服:215959384
    芍药苷元酮; Paeoniflorigenone CFN96022 80454-42-8 C17H18O6 = 318.3 5mg QQ客服:215959384
    芍药内苷B; Paeonilactone B CFN96055 98751-78-1 C10H12O4 = 196.2 5mg QQ客服:1457312923
    芍药内苷C; Paeonilactone C CFN96056 98751-77-0 C17H18O6 = 318.3 5mg QQ客服:1457312923
    芍药内苷A; Paeonilactone A CFN96059 98751-79-2 C10H14O4 = 198.2 5mg QQ客服:2056216494
    苯甲酰芍药内酯苷; Benzoylalbiflorin CFN91579 184103-78-4 C30H32O12 = 584.6 10mg QQ客服:215959384
    芍药苷; Paeoniflorin CFN99544 23180-57-6 C23H28O11 = 480.45 20mg QQ客服:2159513211
    氧化芍药苷; Oxypaeoniflorin CFN99589 39011-91-1 C23H28O12 = 496.46 20mg QQ客服:215959384

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