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  • Arjunglucoside I

    Arjunglucoside I

    Arjunglucoside I
    产品编号 CFN95049
    CAS编号 62319-70-4
    分子式 = 分子量 C36H58O11 = 666.9
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Triterpenoids
    植物来源 The leaves of Forsythia suspensa
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    Arjunglucoside I CFN95049 62319-70-4 1mg QQ客服:1413575084
    Arjunglucoside I CFN95049 62319-70-4 5mg QQ客服:1413575084
    Arjunglucoside I CFN95049 62319-70-4 10mg QQ客服:1413575084
    Arjunglucoside I CFN95049 62319-70-4 20mg QQ客服:1413575084
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • Universidade de Franca (Brazil)
  • Shanghai University of TCM (China)
  • Seoul National University of Science and Technology (Korea)
  • Universidad de La Salle (Mexico)
  • University of Helsinki (Finland)
  • Sapienza University of Rome (Italy)
  • Celltrion Chemical Research Institute (Korea)
  • Monash University Malaysia (Malaysia)
  • Rio de Janeiro State University (Brazil)
  • Aarhus University (Denmark)
  • University of Wisconsin-Madison (USA)
  • University of Parma (Italy)
  • Uniwersytet Jagielloński w Krakowie (Poland)
  • Universiti Sains Malaysia (Malaysia)
  • More...
  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • J Ethnopharmacol.2023, 321:117501.
  • Nanjing University of Chinese Medicine2022, 345930.
  • Molecules.2017, 22(3)
  • Chemistry of Plant Raw Materials2019, 4:135-147
  • J Nat Med.2020, 74(3):550-560.
  • Planta Medica International2022, 9(01):e108-e115.
  • Life Sci.2022, 298:120488.
  • Sci Rep.2016, 6:25094
  • Front Pharmacol.2021, 12:770667.
  • J of Apicultural Research2020, 10.1080
  • Hindawi J of Food Biochemistry2023, P17:8883860
  • J Nat Prod.2022, doi: 10.1021
  • Biochem Biophys Res Commun.2020, 522(1):40-46
  • Oxid Med Cell Longev.2022, 2022:5888636.
  • Scientific World Journal.2014, 2014:654193
  • J Pharmaceut Biomed2020, 182:113110
  • Pharmaceuticals (Basel).2022, 15(8):982.
  • J Anal Toxicol.2021, bkab015.
  • Virus Res.2023, 335:199199.
  • FEBS Lett.2015, 589(1):182-7
  • Current Traditional Medicine, 2021, 7:326-335(10).
  • Int J Mol Sci.2022, 23(20):12516.
  • J of the Korean Society of Cosmetics and Cosmetology2019, 225-231
  • ...
  • 生物活性
    Description: Arjunglucoside I has anti-inflammatory activity, it exhibits significant activity against carrageenan-induced paw edema in rat. It also shows antiproliferative activity against the A2780 human ovarian cancer cell line with an IC(50) value of 1.2 microM.
    Targets: Immunology & Inflammation related
    In vitro:
    Phytochemistry. 2010 Jan;71(1):95-9.
    Saponins and a lignan derivative of Terminalia tropophylla from the Madagascar Dry Forest.[Pubmed: 19875137]
    A study of an EtOH extract obtained from the roots of the Madagascan plant Terminalia tropophylla H. Perrier (Combretaceae) led to isolation of the oleanane-type triterpenoid saponin 1, the lignan derivative 2, and the two known saponins arjunglucoside I (3) and sericoside (4).
    METHODS AND RESULTS:
    The structures of compounds 1 (terminaliaside A) and 2 (4'-O-cinnamoyl cleomiscosin A) were elucidated using 1D and 2D NMR experiments and mass spectrometry. Compound 1 showed antiproliferative activity against the A2780 human ovarian cancer cell line with an IC(50) value of 1.2 microM.
    In vivo:
    Phytochemistry Letters, 2008, 1(4):183-187.
    Polyhydroxyoleanane-type triterpenoids from Combretum molle and their anti-inflammatory activity.[Reference: WebLink]
    A new oleanane-type triterpene saponin, β-d-glucopyranosyl 2α,3β,6β-trihydroxy-23-galloylolean-12-en-28-oate (1), together with four known oleanane-type pentacyclic triterpenoids, combregenin (2), arjungenin (3), arjunglucoside I (4), and combreglucoside (5) were isolated from the stem bark of Combretum molle.
    METHODS AND RESULTS:
    Their structures were established mainly on the basis of 1D and 2D NMR spectral data. Compounds 1–3 exhibited more significant activity against carrageenan-induced paw edema in rat compared to compounds 4 and 5.Graphical abstractThe new triterpene saponin, β-d-glucopyranosyl 2α,3β,6β-trihydroxy-23-galloylolean-12-en-28-oate (1) together with the known combregenin (2), arjungenin (3), arjunglucoside I (4), and combreglucoside (5) were isolated from the stem bark of Combretum molle.
    CONCLUSIONS:
    Their structures were identified by interpretation of their spectral data, mainly ESIMS, 1D NMR (1H, 13C NMR, DEPT) and 2D NMR (COSY, HSQC and HMBC), and by comparison with the literature. Compounds 1–3 exhibited more significant anti-inflammatory activity against carrageenan-induced paw edema in rat compared to compounds 4 and 5.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 1.4995 mL 7.4974 mL 14.9948 mL 29.9895 mL 37.4869 mL
    5 mM 0.2999 mL 1.4995 mL 2.999 mL 5.9979 mL 7.4974 mL
    10 mM 0.1499 mL 0.7497 mL 1.4995 mL 2.999 mL 3.7487 mL
    50 mM 0.03 mL 0.1499 mL 0.2999 mL 0.5998 mL 0.7497 mL
    100 mM 0.015 mL 0.075 mL 0.1499 mL 0.2999 mL 0.3749 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    两头尖皂苷R9; Raddeanoside R9 CFN95636 124961-62-2 C65H106O31 = 1383.6 5mg QQ客服:1413575084
    两头尖皂苷R18; Raddeanoside R18 CFN95630 781676-86-6 C65H106O31 = 1383.6 5mg QQ客服:2159513211
    Clematichinenoside C; Clematichinenoside C CFN90971 177912-24-2 C70H114O34 = 1499.65 5mg QQ客服:2056216494
    白头翁皂苷E3; Pulchinenoside E3 CFN80363 824401-07-2 C71H116O35 = 1529.66 5mg QQ客服:1457312923
    Clematiunicinoside E; Clematiunicinoside E CFN90903 916649-92-8 C76H124O39 = 1661.79 5mg QQ客服:1457312923
    Clematomandshurica saponin B; Clematomandshurica saponin B CFN90904 916649-91-7 C92H142O46 = 1984.10 5mg QQ客服:3257982914
    常春藤皂苷元 28-O-beta-D-吡喃葡萄糖酯; Hederagenin 28-O-beta-D-glucopyranosyl ester CFN90651 53931-25-2 C36H58O9 = 634.9 10mg QQ客服:1413575084
    Arjunglucoside II; Arjunglucoside II CFN89144 62369-72-6 C36H58O10 = 650.85 5mg QQ客服:1413575084
    泰国树脂酸-28-O-β-D-葡萄糖酯苷; Siaresinolic acid 28-O-beta-D-glucopyranosyl ester CFN91847 155653-86-4 C36H58O9 = 634.9 5mg QQ客服:2159513211
    Arjunetin; Arjunetin CFN91151 31297-79-7 C36H58O10 = 650.9 5mg QQ客服:2159513211

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