Info: Read More
  • 中药标准品生产商,产品定制服务
  • 当归醇B

    Angelol B

    当归醇B
    产品编号 CFN91000
    CAS编号 83156-04-1
    分子式 = 分子量 C20H24O7 = 376.4
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Coumarins
    植物来源 The roots of Angelica sinensis
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    当归醇B CFN91000 83156-04-1 1mg QQ客服:1457312923
    当归醇B CFN91000 83156-04-1 5mg QQ客服:1457312923
    当归醇B CFN91000 83156-04-1 10mg QQ客服:1457312923
    当归醇B CFN91000 83156-04-1 20mg QQ客服:1457312923
    存储与注意事项
    1. 在您收到产品后请检查产品。如无问题,请将产品存入冰霜并且样品瓶保持密封,产品可以存放长达24个月(2-8摄氏度)。

    2. 只要有可能,产品溶解后,您应该在同一天应用于您的实验。 但是,如果您需要提前做预实验,或者需要全部溶解,我们建议您将溶液以等分试样的形式存放在-20℃的密封小瓶中。 通常,这些可用于长达两周。 使用前,打开样品瓶前,我们建议您将产品平衡至室温至少1小时。

    3. 需要更多关于溶解度,使用和处理的建议? 请发送电子邮件至:service@chemfaces.com
    订购流程
  • 1. 在线订购
  • 请联系我们QQ客服

  • 2. 电话订购
  • 请拨打电话:
    027-84237683 或 027-84237783

  • 3. 邮件或传真订购
  • 发送电子邮件到: manager@chemfaces.com 或
    发送传真到:027-84254680

  • 提供订购信息
  • 为了方便客户的订购,请需要订购ChemFaces产品的客户,在下单的时候请提供下列信息,以供我们快速为您建立发货信息。
  •  
  • 1. 产品编号(CAS No.或产品名称)
  • 2. 发货地址
  • 3. 联系方法 (联系人,电话)
  • 4. 开票抬头 (如果需要发票的客户)
  • 5. 发票地址(发货地址与发票地址不同)
  • 发货时间
    1. 付款方式为100%预付款客户,我们将在确认收到货款后当天或1-3个工作日发货。

    2. 付款方式为月结的客户,我们承诺在收到订单后当天或1-3个工作日内发货。

    3. 如果客户所需要的产品,需要重新生产,我们有权告知客户,交货时间需要延期。
    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • Uniwersytet Gdański (Poland)
  • University of Indonesia (Indonesia)
  • Cornell University (USA)
  • University of Toronto (Canada)
  • University of Auckland (New Zealand)
  • Massachusetts General Hospital (USA)
  • University of Amsterdam (Netherlands)
  • Universita' Degli Studi Di Cagliari (Italy)
  • Universidade do Porto (Portugal)
  • Chang Gung University (Taiwan)
  • University of Brasilia (Brazil)
  • University of Bordeaux (France)
  • Centralised Purchases Unit (CPU), B.I.T.S (India)
  • Universidade Federal de Santa Catarina (Brazil)
  • More...
  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Nutr Res Pract2019, 13:e45
  • Vet World.2023, 16(3):618-630.
  • Plant Cell, Tissue and Organ Culture (PCTOC)2020, 143, 45-60(2020)
  • Journal of Chromatography A2020, 460942
  • BMC Pharmacol Toxicol.2018, 19(1):5
  • Appl. Sci.2021, 11(1),14.
  • Drug Dev Res.2020, doi: 10.1002
  • Int J Mol Sci.2022, 23(15):8687.
  • Functional Ecology2020, doi: 10.1111.
  • Pharmacol Res.2020, 161:105205.
  • Indian J Pharm Sci.2022, 84(4): 874-882.
  • Curr Issues Mol Biol.2022, 44(5):2300-2308.
  • Front Plant Sci.2022, 12:811166.
  • Phytother Res.2019, 33(4):1104-1113
  • Int. J. of Food Properties2017, S108-S118
  • Vojnosanit Pregl2016, 75(00):391-391
  • Plant Physiol Biochem.2023, 203:108073.
  • JPC-Journal of Planar Chromatography 2017, 30(2)
  • Antioxidants.2022, 11(4), 67.
  • Evid Based Complement Alternat Med.2021, 2021:8850744.
  • Biocell2023, 47(8):1793-1802
  • Front Pharmacol.2016, 7:460
  • Integr Med Res.2017, 6(4):395-403
  • ...
  • 生物活性
    Description: The absorption and transport of angelol A and Angelol B are passive diffusion as the dominating process in Caco-2 cell monolayer model.
    In vitro:
    Zhong Xi Yi Jie He Xue Bao. 2008 Apr;6(4):392-8.
    Absorption and transport of 6 coumarins isolated from the roots of Angelica pubescens f. biserrata in human Caco-2 cell monolayer model.[Pubmed: 18405608]
    The absorption and transport of six coumarins were passive diffusion as the dominating process.
    METHODS AND RESULTS:
    The P(app) values of umbelliferone, osthole, columbianadin, columbianetin acetate, angelol A and Angelol B from AP to BL side were (2.679+/-0.263) x 10(-5), (1.306+/-0.324) x 10(-5), (0.595+/-0.086) x 10(-6), (2.930+/-0.410) x 10(-6), (1.532+/-0.444) x 10(-5) and (1.413+/-0.243) x 10(-5) cm/s, and from BL to AP side were (3.381+/-0.410) x 10(-5), (0.898+/-0.134) x 10(-5), (0.510+/-0.183) x 10(-6), (0.222+/-0.025) x 10(-6), (1.203+/-0.280) x 10(-5) and (0.754+/-0.092) x 10(-5) cm/s, respectively. In this assay, the P(app) value of propranolol was 2.18 x 10(-5) cm/s and the P(app) value of atenolol was 2.77 x 10(-7) cm/s. Among the 6 coumarins, the P(app) values of umbelliferone, osthole, angelol A and Angelol B from AP to BL side were identical with that of propranolol, and columbianadin and columbianetin acetate lied between propranolol and atenolol. When replaced the HBSS with EBSS, and iodoacetamide or MK-591 were used in the experiment, the P(app) of Angelol B had no statistical difference as compared with the control group. In the mean total recoveries, umbelliferone was (83.31+/-3.52)%, angelol A was (77.39+/-7.38)%, osthole, columbianadin and Angelol B were between 50% to 65%, and columbianetin acetate was lower than 10%. The accumulation rates of osthole and columbianadin in the Caco-2 cells were (36.15+/-5.87)% and (53.90+/-4.39)%, respectively.
    CONCLUSIONS:
    The absorption and transport of umbelliferone, osthole, columbianadin, columbianetin acetate, angelol A and Angelol B are passive diffusion as the dominating process in Caco-2 cell monolayer model. Umbelliferone, osthole, angelol A and Angelol B are estimated to be highly absorbed compounds, and columbianadin and columbianetin acetate are estimated to be moderately absorbed compounds. In the Caco-2 cells, osthol and columbianadin appear to accumulate, and columbianetin acetate may be metabolized. The absorption and transport of Angelol B are not influenced by the change of pH and the presence of iodoacetamide or MK571.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 2.6567 mL 13.2837 mL 26.5675 mL 53.135 mL 66.4187 mL
    5 mM 0.5313 mL 2.6567 mL 5.3135 mL 10.627 mL 13.2837 mL
    10 mM 0.2657 mL 1.3284 mL 2.6567 mL 5.3135 mL 6.6419 mL
    50 mM 0.0531 mL 0.2657 mL 0.5313 mL 1.0627 mL 1.3284 mL
    100 mM 0.0266 mL 0.1328 mL 0.2657 mL 0.5313 mL 0.6642 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    当归醇B; Angelol B CFN91000 83156-04-1 C20H24O7 = 376.4 10mg QQ客服:1413575084
    当归醇K; Angelol K CFN80136 169736-93-0 C20H24O7 = 376.15 5mg QQ客服:3257982914
    当归醇G; Angelol G CFN92988 83199-38-6 C20H24O7 = 376.40 10mg QQ客服:2056216494
    当归醇H; Angelol H CFN91925 83247-73-8 C20H24O7 = 376.40 5 mg QQ客服:3257982914
    飞龙掌血内酯; Toddaculine CFN92733 4335-12-0 C16H18O4 = 274.3 10mg QQ客服:3257982914
    毛两面针素; Toddalolactone CFN90247 483-90-9 C16H20O6 = 308.33 20mg QQ客服:3257982914
    毛两面针素3'-O-甲醚; Toddalolactone 3'-O-methyl ether (6-(2-Hydroxy-3-methoxy-3-methylbutyl)-5,7-dimethoxycoumarin) CFN95372 143614-35-1 C17H22O6 = 322.4 10mg QQ客服:3257982914
    (-)-飞龙掌血烯醇内酯; (-)-Toddanol CFN92513 77715-99-2 C16H18O5 = 290.3 5mg QQ客服:1413575084
    飞龙掌血内酯酮; Toddanone CFN92514 77636-08-9 C16H18O5 = 290.3 5mg QQ客服:1457312923
    5-Methoxysuberenone; 5-Methoxysuberenone CFN92732 85011-58-1 C15H14O5 = 274.3 5mg QQ客服:215959384

    信息支持


    公司简介
    订购流程
    付款方式
    退换货政策

    ChemFaces提供的产品仅用于科学研究使用,不用于诊断或治疗程序。

    联系方式


    电机:027-84237783
    传真:027-84254680
    在线QQ: 1413575084
    E-Mail:manager@chemfaces.com

    湖北省武汉沌口经济技术开区车城南路83号1号楼第三层厂房


    ChemFaces为科学家,科研人员与企业提供快速的产品递送。我们通过瑞士SGS ISO 9001:2008质量体系认证天然化合物与对照品的研发和生产