Info: Read More
  • 中药标准品生产商,产品定制服务
  • 泽泻醇F

    Alisol F

    泽泻醇F
    产品编号 CFN92402
    CAS编号 155521-45-2
    分子式 = 分子量 C30H48O5 = 488.7
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Triterpenoids
    植物来源 The tubers of Alisma plantago-aquatica Linn.
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    泽泻醇F CFN92402 155521-45-2 1mg QQ客服:1413575084
    泽泻醇F CFN92402 155521-45-2 5mg QQ客服:1413575084
    泽泻醇F CFN92402 155521-45-2 10mg QQ客服:1413575084
    泽泻醇F CFN92402 155521-45-2 20mg QQ客服:1413575084
    存储与注意事项
    1. 在您收到产品后请检查产品。如无问题,请将产品存入冰霜并且样品瓶保持密封,产品可以存放长达24个月(2-8摄氏度)。

    2. 只要有可能,产品溶解后,您应该在同一天应用于您的实验。 但是,如果您需要提前做预实验,或者需要全部溶解,我们建议您将溶液以等分试样的形式存放在-20℃的密封小瓶中。 通常,这些可用于长达两周。 使用前,打开样品瓶前,我们建议您将产品平衡至室温至少1小时。

    3. 需要更多关于溶解度,使用和处理的建议? 请发送电子邮件至:service@chemfaces.com
    订购流程
  • 1. 在线订购
  • 请联系我们QQ客服

  • 2. 电话订购
  • 请拨打电话:
    027-84237683 或 027-84237783

  • 3. 邮件或传真订购
  • 发送电子邮件到: manager@chemfaces.com 或
    发送传真到:027-84254680

  • 提供订购信息
  • 为了方便客户的订购,请需要订购ChemFaces产品的客户,在下单的时候请提供下列信息,以供我们快速为您建立发货信息。
  •  
  • 1. 产品编号(CAS No.或产品名称)
  • 2. 发货地址
  • 3. 联系方法 (联系人,电话)
  • 4. 开票抬头 (如果需要发票的客户)
  • 5. 发票地址(发货地址与发票地址不同)
  • 发货时间
    1. 付款方式为100%预付款客户,我们将在确认收到货款后当天或1-3个工作日发货。

    2. 付款方式为月结的客户,我们承诺在收到订单后当天或1-3个工作日内发货。

    3. 如果客户所需要的产品,需要重新生产,我们有权告知客户,交货时间需要延期。
    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • Korea Food Research Institute(KFRI) (Korea)
  • Nicolaus Copernicus Uniwersity (Poland)
  • Chungnam National University (Korea)
  • Instituto de Investigaciones Agropecuarias (Chile)
  • Tokyo Woman's Christian University (Japan)
  • Charles University in Prague (Czech Republic)
  • University of Toronto (Canada)
  • University of Hertfordshire (United Kingdom)
  • Agricultural Research Organization (ARO) (Israel)
  • Universidade de Franca (Brazil)
  • Harvard University (USA)
  • Institute of Tropical Disease Universitas Airlangga (Indonesia)
  • Guangzhou Institutes of Biomedicine and Health (China)
  • Mahatma Gandhi University (India)
  • More...
  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Phytother Res.2022, 10.1002:ptr.7602.
  • Asian J Beauty Cosmetol2022, 20(2):183-191
  • Phytother Res.2023, 37(10):4587-4606.
  • Pak J Pharm Sci.2019, 32(6)
  • BMB Rep.2020, 53(4):218-222.
  • Journal of Molecular Liquids2022, 364:120062.
  • Eur J Pharm Sci.2016, 94:33-45
  • Int J Food Sci Nutr.2019, 70(7):825-833
  • J Pharm Biomed Anal.2019, 172:268-277
  • Microb Pathog.2019, 131:128-134
  • Appl. Sci.2021, 11(19),9343.
  • Braz J Med Biol Res. 2016, 49(7)
  • Microchemical Journal2018, 137:168-173
  • Molecules.2018, 23(3):E615
  • J Sep Sci.2018, 41(7):1682-1690
  • Pharmaceuticals (Basel).2020, 13(10):302.
  • Biomed Chromatogr.2019, 8:e4774
  • J Nutr Biochem.2022, 107:109064.
  • Arch Toxicol.2017, 91(10):3225-3245
  • Biomed Pharmacother.2022, 145:112410.
  • Pharmaceutics.2021, 13(2):187.
  • Advances in Traditional Medicine 2021, 21:779-789.
  • Analytical sci. & Tech2020, 33(5):224-231
  • ...
  • 生物活性
    Description: Alisol F shows anti-inflammatory activities and liver protectionthrough the inhibition of MAPK, STAT3, and NF-κB activation in vitro and in vivo, it suppresses iNOS induction. Alisol F exhibits inhibitory activity in vitro on hepatitis B virus (HBV) surface antigen (HBsAg) secretion of the Hep G2.2.15 cell line with the IC (50) value of 0.6 microM, and on HBV e antigen (HBeAg) secretion with the IC (50) value of 8.5 microM.
    Targets: NOS | NO | TNF-α | IL Receptor | COX | STAT | NF-kB | ERK | JNK | p38MAPK | HBsAg | HBeAg
    In vitro:
    Zhongguo Zhong Yao Za Zhi. 2009 Apr;34(8):994-8.
    Chemical constituents of Alisma orientalis and their immunosuppressive function.[Pubmed: 19639784]
    To investigate the chemical constituents with immunosuppressive function from Alisma orientalis.
    METHODS AND RESULTS:
    The chemical constituents were isolated and purified by kinds of column chromatography and its structures were elucidated by NMR spectra and physicochemical properties. Its immunocompentence of lymphocytes taken from spleen of mouse were examined by MTT assay. Twelve compounds were isolated and identified as clovandiol (1), orientalol E (2), alismoxide (3), alismol (4), 4alpha, l0alpha-dihydroxy-5beta-H-guaj-6-en (5), alismorientols A (6), alisol F (7), alisol A (8), 13beta,17beta-epoxy alisol A (9), alisol B 23-acetate (10), 1H-indole-3-carboxylic acid (11) and cuccinic acid (12). Compounds 9, 10 and alisol A 24-acetate showed immunosuppressive function.
    CONCLUSIONS:
    Compounds 1, 5, 11 and 12 were isolated firstly from this genus,and the NMR spectra data of 1 were corrected firstly, some protostan-type triterpenoids may be developed as new drug with immunosuppressive function.
    Bioorg Med Chem Lett. 1999 Nov 1;9(21):3081-6.
    Effects of sesquiterpenes and triterpenes from the rhizome of Alisma orientale on nitric oxide production in lipopolysaccharide-activated macrophages: absolute stereostructures of alismaketones-B 23-acetate and -C 23-acetate.[Pubmed: 10560729]
    The methanolic extract from a Chinese herbal medicine, the rhizome of Alisma orientale, was found to exhibit inhibitory activity of nitric oxide (NO) production in lipopolysaccharide (LPS)activated macrophages.
    METHODS AND RESULTS:
    Novel triterpenes, alismaketones-B 23-acetate and -C 23-acetate, were isolated from the active extract together with eight sesquiterpenes and eighteen protostane-type triterpenes. The absolute stereostructures of new triterpenes were characterized on the basis of chemical and physicochemical evidence, which included the chemical correlations with known triterpenes. The guaiane-type sesquiterpenes (alismol, orientalols A and C) and protostane- and seco-protostane-types triterpenes (alisols C monoacetate, E-23-acetate, F, H, I, L-23-acetate, and M-23-acetate, alismaketones-B 23-acetate and -C 23-acetate, alismalactone 23-acetate, and 3-methylalismalactone 23-acetate) inhibited LPS-induced NO production (IC50 = 8.4-68 microM). Other triterpenes (alisols A, A monoacetate, B, B monoacetate, E, G, K-23-acetate, and N-23-acetate and 11-deoxyalisol B) also showed the potent inhibitory activity, but they showed cytotoxic effects more than 30 microM (MTT assay). In addition, alismol and alisol F were found to suppress iNOS induction.
    Planta Med. 2006 Aug;72(10):951-4.
    A new triterpene and anti-hepatitis B virus active compounds from Alisma orientalis.[Pubmed: 16858666 ]
    A new triterpenoid named alisol O ( 1) was isolated from the rhizomes of Alisma orientalis, together with six known compounds: alisol A 24-acetate ( 2), 25-anhydroalisol A ( 3), 13 beta,17 beta-epoxyalisol A ( 4), alisol B 23-acetate ( 5), alisol F ( 6), and alisol F 24-acetate ( 7).
    METHODS AND RESULTS:
    Based on 1D and 2D-NMR data (HMQC, HMBC, COSY, ROESY), the structure of the new compound was deduced to be 11-dehydroxy-12-dehydroalisol F-24-acetate ( 1). Compounds 2 - 7 exhibited inhibitory activity in vitro on hepatitis B virus (HBV) surface antigen (HBsAg) secretion of the Hep G2.2.15 cell line with IC (50) values of 2.3, 11.0, 15.4, 14.3, 0.6 and 7.7 microM, and on HBV e antigen (HBeAg) secretion with IC (50) values of 498.1, 17.6, 41.0, 19.9, 8.5 and 5.1 microM, respectively.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 2.0462 mL 10.2312 mL 20.4625 mL 40.9249 mL 51.1561 mL
    5 mM 0.4092 mL 2.0462 mL 4.0925 mL 8.185 mL 10.2312 mL
    10 mM 0.2046 mL 1.0231 mL 2.0462 mL 4.0925 mL 5.1156 mL
    50 mM 0.0409 mL 0.2046 mL 0.4092 mL 0.8185 mL 1.0231 mL
    100 mM 0.0205 mL 0.1023 mL 0.2046 mL 0.4092 mL 0.5116 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    16-氧代泽泻醇A; 16-Oxoalisol A CFN92547 124515-98-6 C30H48O6 = 504.7 5mg QQ客服:3257982914
    泽泻醇C; Alisol C CFN92545 30489-27-1 C30H46O5 = 486.7 5mg QQ客服:3257982914
    泽泻醇 C-23-醋酸酯; Alisol C monoacetate CFN90199 26575-93-9 C32H48O6 = 528.73 20mg QQ客服:1413575084
    泽泻醇 K 23-醋酸酯; Alisol K 23-acetate CFN92405 228095-18-9 C32H46O6 = 526.7 5mg QQ客服:215959384
    苦玄参苷IA; Picfeltarraenin IA CFN99942 97230-47-2 C41H62O13 = 762.92 20mg QQ客服:1413575084
    苦玄参苷IB; Picfeltarraenin IB CFN90712 97230-46-1 C42H64O14 = 792.95 20mg QQ客服:1457312923
    苦玄参苷IV; Picfeltarraenin IV CFN90719 184288-35-5 C47H72O18 = 925.06 5mg QQ客服:215959384
    苦玄参苷X; Picfeltarraenin X CFN90730 1391826-61-1 C36H54O11 = 662.81 5mg QQ客服:2159513211
    16,23-氧化泽泻醇B; 16,23-Oxidoalisol B CFN95650 169326-06-1 C30H46O4 = 470.7 5mg QQ客服:3257982914
    泽泻醇F; Alisol F CFN92402 155521-45-2 C30H48O5 = 488.7 10mg QQ客服:2056216494

    信息支持


    公司简介
    订购流程
    付款方式
    退换货政策

    ChemFaces提供的产品仅用于科学研究使用,不用于诊断或治疗程序。

    联系方式


    电机:027-84237783
    传真:027-84254680
    在线QQ: 1413575084
    E-Mail:manager@chemfaces.com

    湖北省武汉沌口经济技术开区车城南路83号1号楼第三层厂房


    ChemFaces为科学家,科研人员与企业提供快速的产品递送。我们通过瑞士SGS ISO 9001:2008质量体系认证天然化合物与对照品的研发和生产