粗叶悬钩子甙

Alcesefoliside

	产品编号	CFN90820
	CAS编号	124151-38-8
	分子式 = 分子量	C₃₃H₄₀O₂₀ = 756.7
	产品纯度	>=98%
	物理属性	Yellow powder
	化合物类型	Flavonoids
	植物来源	The herbs of Rubus alceaefolius Poir.
ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用

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产品名称	产品编号	CAS编号	包装	QQ客服
粗叶悬钩子甙	CFN90820	124151-38-8	1mg	QQ客服：3257982914
粗叶悬钩子甙	CFN90820	124151-38-8	5mg	QQ客服：3257982914
粗叶悬钩子甙	CFN90820	124151-38-8	10mg	QQ客服：3257982914
粗叶悬钩子甙	CFN90820	124151-38-8	20mg	QQ客服：3257982914

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ChemFaces的产品在许多优秀和顶级科学期刊中被引用

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089

Shanghai University of TCM (China)

Funda??o Universitária de Desenvolvimento (Brazil)

Vin?a Institute of Nuclear Sciences (Serbia)

Srinakharinwirot University (Thailand)

Chinese University of Hong Kong (China)

University of Liège (Belgium)

Donald Danforth Plant Science Center (USA)

University of Indonesia (Indonesia)

University of Helsinki (Finland)

Max Rubner-Institut (MRI) (Germany)

University of Illinois at Chicago (USA)

Mahidol University (Thailand)

Cancer Research Initatives Foundation(CARIF) (Malaysia)

National Chung Hsing University (Taiwan)

More...

Description:

Alcesefoliside has statistically significant cytoprotective activity similar to that of silymarin, tested at 60 ug/mL.

In vitro:

J Nat Prod. 2015 Nov 25;78(11):2565-71.

Flavoalkaloids and Flavonoids from Astragalus monspessulanus.[Pubmed: 26558405]

METHODS AND RESULTS:
A new flavonol tetraglycoside, quercetin-3-O-[α-L-rhamnopyranosyl-(1→2)-[α-L-rhamnopyranosyl-(1→6)]-β-D-galactopyranosyl]-7-O-β-D-glucopyranoside (1), and two new flavonol alkaloids, N-(8-methylquercetin-3-O-[α-L-rhamnopyranosyl-(1→2)-[α-L-rhamnopyranosyl-(1→6)]-β-D-galactopyranosyl])-3-hydroxypiperidin-2-one (2) and N-(8-methylkaempferol-3-O-[α-L-rhamnopyranosyl-(1→2)-[α-L-rhamnopyranosyl-(1→6)]-β-D-galactopyranosyl])-3-hydroxypiperidin-2-one (3), were isolated from the aerial parts of Astragalus monspessulanus ssp. monspessulanus. Two rare flavonoids with an unusual 3-hydroxy-3-methylglutaric acid moiety, quercetin-3-O-α-L-rhamnopyranosyl-(1→2)-[6-O-(3-hydroxy-3-methylglutaryl)-β-D-galactopyranoside (4) and kaempferol-3-O-α-L-rhamnopyranosyl-(1→2)-[6-O-(3-hydroxy-3-methylglutaryl)-β-D-galactopyranoside (5), were isolated from the aerial parts of A. monspessulanus ssp. illyricus. In addition, the eight known flavonoids alangiflavoside (6), alcesefoliside (7), mauritianin (8), quercetin-3-β-robinobioside (9), cosmosine (10), apigenin-4'-O-glucoside (11), trifolin (12), and rutin (13) were isolated from aerial parts of A. monspessulanus ssp. monspessulanus. Their structures were elucidated via NMR and HRESIMS data.
CONCLUSIONS:
In a model that tested t-BuOOH-induced oxidative stress on isolated rat hepatocytes, flavonoids 1-13 had statistically significant cytoprotective activity similar to that of silymarin, tested at 60 μg/mL. The most prominent effects were observed for flavonoids 1, 4, 7, and 12.

产品名称	产品编号	CAS编号	分子式 = 分子量	位单	联系QQ
3,4,4a,9,10,10a-heexahydro-8-hydroxy-1-(hydroxymethyl)-1,4a-dimethyl-7-(1-methylethyl)-phenanthrene-2(1H)-one; 3,4,4a,9,10,10a-heexahydro-8-hydroxy-1-(hydroxymethyl)-1,4a-dimethyl-7-(1-methylethyl)-phenanthrene-2(1H)-one	CFN94020	262599-12-2	C₂₁H₃₀O₃ = 330.46	5mg	QQ客服：2056216494
20(S)-原人参三醇; (20S)-Protopanaxatriol	CFN90564	34080-08-5	C₃₀H₅₂O₄ = 476.4	20mg	QQ客服：215959384
圣草酚 7,3',4'-三甲醚; 7,3',4'-Tri-O-methyleriodictyol	CFN89491	70987-96-1	C₁₈H₁₈O₆ = 330.33	5mg	QQ客服：3257982914
刺五加甙C; Eleutheroside C	CFN99650	15486-24-5	C₈H₁₆O₆ = 208.2	5mg	QQ客服：3257982914

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	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	1.3215 mL	6.6076 mL	13.2153 mL	26.4306 mL	33.0382 mL
5 mM	0.2643 mL	1.3215 mL	2.6431 mL	5.2861 mL	6.6076 mL
10 mM	0.1322 mL	0.6608 mL	1.3215 mL	2.6431 mL	3.3038 mL
50 mM	0.0264 mL	0.1322 mL	0.2643 mL	0.5286 mL	0.6608 mL
100 mM	0.0132 mL	0.0661 mL	0.1322 mL	0.2643 mL	0.3304 mL