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  • 3-beta-O-反式-对-香豆酰马期里酸

    3-beta-O-(trans-p-Coumaroyl)maslinic acid

    3-beta-O-反式-对-香豆酰马期里酸
    产品编号 CFN92210
    CAS编号 35482-91-8
    分子式 = 分子量 C39H54O6 = 618.9
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Triterpenoids
    植物来源 From Faeces Trogopterpri
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    3-beta-O-反式-对-香豆酰马期里酸 CFN92210 35482-91-8 1mg QQ客服:1457312923
    3-beta-O-反式-对-香豆酰马期里酸 CFN92210 35482-91-8 5mg QQ客服:1457312923
    3-beta-O-反式-对-香豆酰马期里酸 CFN92210 35482-91-8 10mg QQ客服:1457312923
    3-beta-O-反式-对-香豆酰马期里酸 CFN92210 35482-91-8 20mg QQ客服:1457312923
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    Cell. 2018 Jan 11;172(1-2):249-261.e12.
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    IF=36.216(2019)

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  • ...
  • 生物活性
    Description: 3-beta-O-(trans-p-Coumaroyl)maslinic acid is a DNA polymerase B" inhibitor. It shows antimicrobial activity on Gram-positive bacteria and yeasts.
    Targets: DNA polymerase B" inhibitor | Antifection
    In vitro:
    Planta Medica, 2000, 66(8):768-769.
    Antimicrobial triterpenoids from Licania heteromorpha.[Reference: WebLink]

    METHODS AND RESULTS:
    Six triterpenoids having a lupane and oleane skeleton were isolated from the leaves and young branches of Licania heteromorpha Bentham var. heteromorpha and were identified as: betulinic acid 1, alphitolic acid 2, 3 beta-O-trans-p-coumaroyl alphitolic acid 3, 3 beta-O-cis-p-coumaroyl alphitolic acid 4, 3-beta-O-(trans-p-Coumaroyl)maslinic acid 5, 3 beta-O-cis-p-coumaroyl maslinic acid 6. The antimicrobial activity of these compounds was evaluated in vitro on clinically isolated microorganisms employing a microdilution method.
    CONCLUSIONS:
    Compounds 2, 3, 5, and 6 showed antimicrobial activity on Gram-positive bacteria and yeasts, whereas none of the six triterpenoids were active against Gram-negative organisms.
    Journal of Natural Products, 1999, 62(12):1660-1663.
    DNA polymerase beta inhibitors from Tetracera boiviniana.[Reference: WebLink]

    METHODS AND RESULTS:
    Bioassay-guided fractionation of an active methyl ethyl ketone extract of Tetracera boiviniana, using a sensitive assay to monitor DNA polymerase beta inhibition, resulted in the isolation of three known triterpenoids, betulinic acid (1), 3-cis-p-coumaroyl maslinic acid (2), and 3-beta-O-(trans-p-Coumaroyl)maslinic acid (3).
    CONCLUSIONS:
    Compounds 1-3 inhibited DNA polymerase beta with IC50 values of 14, 15, and 4.2 microM in the presence of bovine serum albumin (BSA) and 6.5, 7.5, and 2.0 microM in the absence of BSA, respectively. Further, compounds 1-3 potentiated the effects of bleomycin in cultured P-388D1 cells.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 1.6158 mL 8.0788 mL 16.1577 mL 32.3154 mL 40.3942 mL
    5 mM 0.3232 mL 1.6158 mL 3.2315 mL 6.4631 mL 8.0788 mL
    10 mM 0.1616 mL 0.8079 mL 1.6158 mL 3.2315 mL 4.0394 mL
    50 mM 0.0323 mL 0.1616 mL 0.3232 mL 0.6463 mL 0.8079 mL
    100 mM 0.0162 mL 0.0808 mL 0.1616 mL 0.3232 mL 0.4039 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    美商陆酸; Phytolaccagenic acid CFN91881 54928-05-1 C31H48O6 = 516.71 5mg QQ客服:1457312923
    商陆皂苷元; Phytolaccagenin CFN99844 1802-12-6 C31H48O7 = 532.7 20mg QQ客服:1457312923
    远志酸; Polygalic acid CFN92195 1260-04-4 C29H44O6 = 488.7 20mg QQ客服:215959384
    苜蓿酸; Medicagenic acid CFN93933 599-07-5 C30H46O6 = 502.68 5mg QQ客服:215959384
    远志皂苷元; Senegenin CFN99109 2469-34-3 C30H45ClO6 = 537.14 20mg QQ客服:1413575084
    皂皮酸; Quillaic acid CFN96689 631-01-6 C30H46O5 = 486.69 5mg QQ客服:1413575084
    3-beta-O-反式-对-香豆酰马期里酸; 3-beta-O-(trans-p-Coumaroyl)maslinic acid CFN92210 35482-91-8 C39H54O6 = 618.9 5mg QQ客服:2159513211
    3-beta-O-顺式-对-香豆酰马期里酸; 3-beta-O-(cis-p-Coumaroyl)maslinic acid CFN92208 69297-40-1 C39H54O6 = 618.9 5mg QQ客服:2159513211
    Eucalyptolic acid; Eucalyptolic acid CFN92275 189272-68-2 C40H56O7 = 648.9 5mg QQ客服:215959384
    脱氢山楂酸; Camaldulenic acid CFN96017 71850-15-2 C30H46O4 = 470.7 5mg QQ客服:215959384

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