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  • 3'-O-Methylmurraol

    3'-O-Methylmurraol

    3'-O-Methylmurraol
    产品编号 CFN89183
    CAS编号 1891097-17-8
    分子式 = 分子量 C16H18O4 = 274.31
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Coumarins
    植物来源 The fruits of Cnidium monnieri.
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    3'-O-Methylmurraol CFN89183 1891097-17-8 1mg QQ客服:1413575084
    3'-O-Methylmurraol CFN89183 1891097-17-8 5mg QQ客服:1413575084
    3'-O-Methylmurraol CFN89183 1891097-17-8 10mg QQ客服:1413575084
    3'-O-Methylmurraol CFN89183 1891097-17-8 20mg QQ客服:1413575084
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • National Cancer Institute (USA)
  • The Ohio State University (USA)
  • Johannes Gutenberg University Mainz (JGU) (Germany)
  • China Medical University (Taiwan)
  • Utrecht University (Netherlands)
  • University of Dicle (Turkey)
  • University of East Anglia (United Kingdom)
  • Institute of Chinese Materia Medica (China)
  • Shanghai Institute of Organic Chemistry (China)
  • Rio de Janeiro State University (Brazil)
  • The Vancouver Prostate Centre (VPC) (Canada)
  • University of Pretoria (South Africa)
  • Subang Jaya Medical Centre (Malaysia)
  • VIB Department of Plant Systems Biology, UGent (PSB) (Belgium)
  • More...
  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Plants (Basel).2020, 9(11):1535.
  • J Inflamm Res.2022, 15:5347-5359.
  • J Sep Sci.2018, 41(9):1938-1946
  • J Ethnopharmacol.2020, 254:112733.
  • Molecules.2021, 26(9):2765.
  • Molecules.2021, 26(12):3652.
  • Food and Fermentation Industries2019, 45(7):45-51
  • Front Pharmacol.2020, 11:251.
  • Agronomy 2021, 11(3),502.
  • Int J Mol Sci.2021, 22(12):6466.
  • Biocell2023, 47(8):1793-1802
  • Institute of Food Science & Technology2021, 45(9).
  • Korean J Dent Mater.2018, 45(2):139-146
  • Appl. Sci.2022, 12(4), 2032.
  • Cell Mol Biol(Noisy-le-grand)2019, 65(7):77-83
  • Asian Journal of Chemistry2018, 30(12):2699-2703
  • Chem Biol Interact.2019, 315:108910
  • J Med Food.2022, 25(3):272-280.
  • Nutrients.2023, 15(3):753.
  • Int J Biol Macromol.2020, 161:1230-1239.
  • Nat Prod Sci.2016, 22(2)
  • Food Chem.2019, 275:746-753
  • J of Essential Oil Research2019, 1677272
  • ...
  • 生物活性
    Description: 3'-O-Methylmurraol may have potential anti-inflammatory activity, it exhibits inhibition (IC50 ≤ 7.31 ug/mL) of superoxide anion generation by human neutrophils in response to formyl-l-methionyl-l-leucyl-l-phenylalanine/cytochalasin B (fMLP/CB).
    Targets: Immunology & Inflammation related
    In vitro:
    Int J Mol Sci. 2014 May 28;15(6):9566-78.
    New coumarins and anti-inflammatory constituents from the fruits of Cnidium monnieri.[Pubmed: 24879527 ]
    The fruit of Cnidium monnieri is commercially used as healthcare products for the improvement of impotence and skin diseases.
    METHODS AND RESULTS:
    Three new coumarins, 3'-O-Methylmurraol (1), rel-(1'S,2'S)-1'-O-methylphlojodicarpin (2), and (1'S,2'S)-1'-O-methylvaginol (3), have been isolated from the fruits of C. monnieri, together with 14 known compounds (4-17). The structures of these new compounds were determined through spectroscopic and MS analyses. Compounds 1, 4-12, and 14-17 exhibited inhibition (IC50 ≤ 7.31 μg/mL) of superoxide anion generation by human neutrophils in response to formyl-l-methionyl-l-leucyl-l-phenylalanine/cytochalasin B (fMLP/CB). Compounds 7, 9-11, 15, and 17 inhibited fMLP/CB-induced elastase release with IC50 values ≤7.83 μg/mL.
    CONCLUSIONS:
    This investigation reveals that bioactive isolates (especially 6, 7, 14, and 17) could be further developed as potential candidates for the treatment or prevention of various inflammatory diseases.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 3.6455 mL 18.2276 mL 36.4551 mL 72.9102 mL 91.1378 mL
    5 mM 0.7291 mL 3.6455 mL 7.291 mL 14.582 mL 18.2276 mL
    10 mM 0.3646 mL 1.8228 mL 3.6455 mL 7.291 mL 9.1138 mL
    50 mM 0.0729 mL 0.3646 mL 0.7291 mL 1.4582 mL 1.8228 mL
    100 mM 0.0365 mL 0.1823 mL 0.3646 mL 0.7291 mL 0.9114 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    九里香酮; Murrayone CFN98505 19668-69-0 C15H14O4 = 258.27 10mg QQ客服:1457312923
    异橙皮内酯 ; Isomeranzin CFN99090 1088-17-1 C15H16O4 = 260.3 20mg QQ客服:2159513211
    橙皮内酯水合物; Meranzin hydrate CFN98994 5875-49-0 C15H18O5 = 278.3 20mg QQ客服:1413575084
    (S)-8-(3-乙氧基-2-羟基-3-甲基丁基)-7-甲氧基-2H-1-苯并吡喃-2-酮; 8-(3-Ethoxy-2-hydroxy-3-methylbutyl)-7-methoxycoumarin CFN99362 125072-68-6 C17H22O5 = 306.4 5mg QQ客服:215959384
    8-(二甲基烯丙基)-7-羟基-6-甲氧基香豆素; Cedrelopsin CFN89410 19397-28-5 C15H16O4 = 260.28 5mg QQ客服:2056216494
    O-Methylcedrelopsin; O-Methylcedrelopsin CFN92731 72916-61-1 C16H18O4 = 274.3 5mg QQ客服:3257982914
    月橘香豆精; 九里香内酯; Coumurrayin CFN99811 17245-25-9 C16H18O4 = 274.3 5mg QQ客服:1413575084
    (S)-8-[(3,3-二甲基环氧乙烷基)甲基]-5,7-二甲氧基-2H-1-苯并吡喃-2-酮; Sibiricin CFN97531 95188-34-4 C16H18O5 = 290.3 5mg QQ客服:2159513211
    九里香甲素; Isomexoticin CFN97454 88585-86-8 C16H20O6 = 308.3 5mg QQ客服:2159513211
    九里香醇; Murraol CFN99097 109741-38-0 C15H16O4 = 260.3 5mg QQ客服:2056216494

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