3-O-Acetyl-16 alpha-hydroxytrametenolic acid

	产品编号	CFN90804
	CAS编号	168293-13-8
	分子式 = 分子量	C₃₂H₅₀O₅ = 514.8
	产品纯度	>=98%
	物理属性	Powder
	化合物类型	Triterpenoids
	植物来源	The sclerotium of Poria cocos(Schw.)Wolf
ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用

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产品名称	产品编号	CAS编号	包装	QQ客服
3-O-Acetyl-16 alpha-hydroxytrametenolic acid	CFN90804	168293-13-8	1mg	QQ客服：2159513211
3-O-Acetyl-16 alpha-hydroxytrametenolic acid	CFN90804	168293-13-8	5mg	QQ客服：2159513211
3-O-Acetyl-16 alpha-hydroxytrametenolic acid	CFN90804	168293-13-8	10mg	QQ客服：2159513211
3-O-Acetyl-16 alpha-hydroxytrametenolic acid	CFN90804	168293-13-8	20mg	QQ客服：2159513211

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ChemFaces的产品在许多优秀和顶级科学期刊中被引用

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Funda??o Universitária de Desenvolvimento (Brazil)

Instytut Nawozów Sztucznych w Pu?awach (Poland)

Macau University of Science and Technology (China)

Siksha O Anusandhan University (India)

Universite de Lille1 (France)

Medizinische Universit?t Wien (Austria)

Institute of Pathophysiology Medical University of Vienna (Austria)

Aarhus University (Denmark)

Anna University (India)

VIT University (India)

University of Sao Paulo (Brazil)

University of Lodz (Poland)

Kazusa DNA Research Institute (Japan)

Northeast Normal University Changchun (China)

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Description:

3-O-Acetyl-16 alpha -hydroxytrametenolic acid has inhibitory activities against AAPH-induced hemolysis of red blood cells, it shows a strong inhibitory activity against 12-O-tetradecanoylphorbol-13-acetate-induced inflammation in mice. 3-O-Acetyl-16 alpha-hydroxytrametenolic acid markedly inhibited the promoting effect of 12-O-tetradecanoylphorbol-13-acetate (1 microgram/mouse) on skin tumor formation following initiation with 7,12-dimethylbenz[a]anthracene (50 micrograms/mouse).

Targets:

Immunology & Inflammation related

In vitro:

Phytother Res. 2003 Feb;17(2):160-2.

Inhibitory effects of triterpenes isolated from Hoelen on free radical-induced lysis of red blood cells.[Pubmed: 12601680 ]

Hoelen, sclederma of Poria cocos Wolf, has long been used as a sedative and diuretic in traditional medicine. Formerly, we demonstrated that Hoelen in vitro protects red blood cells from AAPH-induced hemolysis.
METHODS AND RESULTS:
In this study, tests were carried out to identify the main ingredient of Hoelen that has the scavenging effect on free-radicals. Triterpene carboxylic acids isolated from the methanol extract of Hoelen, i.e. pachymic acid, polyporenic acid, 3-epidehydrotumulosic acid, 3beta-hydroxylanosta-7,9(11), 24-trien-21-oic acid and 3-O-Acetyl-16 alpha-hydroxytrametenolic acid, were found to have inhibitory activities against AAPH-induced lysis of red blood cells.

In vivo:

Oncology. 1996 Sep-Oct;53(5):382-5.

Inhibitory effects of lanostane-type triterpene acids, the components of Poria cocos, on tumor promotion by 12-O-tetradecanoylphorbol-13-acetate in two-stage carcinogenesis in mouse skin.[Pubmed: 8784472]

Pachymic acid, 3-O-Acetyl-16 alpha-hydroxytrametenolic acid, and poricoic acid B had been isolated from the sclerotium of Poria cocos Wolf.
METHODS AND RESULTS:
These compounds showed a strong inhibitory activity against 12-O-tetradecanoylphorbol-13-acetate-induced inflammation in mice. At 0.2 mumol/mouse, these compounds markedly inhibited the promoting effect of 12-O-tetradecanoylphorbol-13-acetate (1 microgram/mouse) on skin tumor formation following initiation with 7,12-dimethylbenz[a]anthracene (50 micrograms/mouse).

产品名称	产品编号	CAS编号	分子式 = 分子量	位单	联系QQ
羊毛甾醇; Lanosterol	CFN92368	79-63-0	C₃₀H₅₀O = 426.7	20mg	QQ客服：1457312923
丁酰鲸鱼醇; Butyrospermol	CFN92376	472-28-6	C₃₀H₅₀O = 426.7	5mg	QQ客服：2159513211
苦楝酮; Kulinone	CFN92977	21688-61-9	C₃₀H₄₈O₂ = 440.70	5mg	QQ客服：2159513211
Aphagranin A ; Aphagranin A	CFN96579	1318173-53-3	C₃₃H₅₄O₆ = 546.79	5mg	QQ客服：2159513211
金钱松呋喃酸; Pseudolarifuroic acid	CFN91924	130825-79-5	C₃₀H₄₂O₄ = 466.65	5mg	QQ客服：2056216494
3-氧代甘遂-7,24-二烯-21-酸; 3-Oxotirucalla-7,24-dien-21-oic acid	CFN97609	82464-35-5	C₃₀H₄₆O₃ = 454.69	5mg	QQ客服：215959384
苦楝萜酸甲酯; Methyl kulonate	CFN92975	22611-37-6	C₃₁H₄₈O₄ = 484.71	5mg	QQ客服：215959384
帕克醇; Parkeol	CFN92825	514-45-4	C₃₀H₅₀O = 426.7	5mg	QQ客服：2159513211
葫芦二烯醇; Cucurbitadienol	CFN92378	35012-08-9	C₃₀H₅₀O = 426.7	5mg	QQ客服：215959384
桦褐孔菌醇; Inotodiol	CFN92367	35963-37-2	C₃₀H₅₀O₂ = 442.7	5mg	QQ客服：2056216494

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	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	1.9425 mL	9.7125 mL	19.425 mL	38.85 mL	48.5625 mL
5 mM	0.3885 mL	1.9425 mL	3.885 mL	7.77 mL	9.7125 mL
10 mM	0.1943 mL	0.9713 mL	1.9425 mL	3.885 mL	4.8563 mL
50 mM	0.0389 mL	0.1943 mL	0.3885 mL	0.777 mL	0.9713 mL
100 mM	0.0194 mL	0.0971 mL	0.1943 mL	0.3885 mL	0.4856 mL